Patents by Inventor Christopher J. Scelonge
Christopher J. Scelonge has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240093214Abstract: Compositions and methods are provided for stacking multiple independent transgenic loci into the genome of a plant. Compositions include plants, seeds or plant cells comprising at least one transgenic target site and at least one genomic locus of interest integrated at different genomic sites within a genomic window. Plant breeding techniques can be employed such that the transgenic target site and the genomic locus of interest can be bred together. In this way, multiple independent transgene integrations can be generated within a genomic window to create a complex trait locus. The complex trait locus is designed such that the transgenic target sites and/or genomic loci of interest can segregate independently of each other, thus providing the benefit of altering a complex trait locus by breeding-in and breeding-away specific elements. Various methods can also be employed to modify the target sites such that they contain a variety of polynucleotides of interest.Type: ApplicationFiled: September 1, 2023Publication date: March 21, 2024Applicants: PIONEER HI-BRED INTERNATIONAL, INC., CORTEVA AGRISCIENCE LLCInventors: SAVERIO CARL FALCO, MICHAEL LASSNSER, ZHONGSEN LI, CHRISTOPHER J. SCELONGE
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Patent number: 11788097Abstract: Compositions and methods are provided for stacking multiple independent transgenic loci into the genome of a plant. Compositions include plants, seeds or plant cells comprising at least one transgenic target site and at least one genomic locus of interest integrated at different genomic sites within a genomic window. Plant breeding techniques can be employed such that the transgenic target site and the genomic locus of interest can be bred together. In this way, multiple independent transgene integrations can be generated within a genomic window to create a complex trait locus. The complex trait locus is designed such that the transgenic target sites and/or genomic loci of interest can segregate independently of each other, thus providing the benefit of altering a complex trait locus by breeding-in and breeding-away specific elements. Various methods can also be employed to modify the target sites such that they contain a variety of polynucleotides of interest.Type: GrantFiled: March 21, 2022Date of Patent: October 17, 2023Assignees: PIONEER HI-BRED INTERNATIONAL, INC., CORTEVA AGRISCIENCE LLCInventors: Saverio Carl Falco, Michael Lassner, Zhongsen Li, Christopher J Scelonge
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Publication number: 20230265448Abstract: Compositions and methods are provided for the introduction and the regulated expression of genes in plants. Compositions include promoter constructs that provide a level of activity useful for the regulated expression of site-specific recombinases, while avoiding premature excision. Further provided are isolated polynucleotides encoding novel babyboom polypeptides, expression cassettes, and plants comprising the same. Methods for the introduction of genes into plants are provided, including methods for plastid transformation and methods for the transformation of tissues from mature seeds and leaves.Type: ApplicationFiled: October 19, 2022Publication date: August 24, 2023Applicants: E. I. DU PONT DE NEMOUS AND COMPANY, PIONEER HI-BRED INTERNATIONAL, INC.Inventors: WILLIAM JAMES GORDON-KAMM, THEODORE M KLEIN, KEITH S LOWE, KEVIN E MCBRIDE, CHRISTOPHER J SCELONGE, NING WANG
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Publication number: 20230220407Abstract: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.Type: ApplicationFiled: January 25, 2023Publication date: July 13, 2023Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: CLARA MARIA ALARCON, MATTHEW C. HARMON, M. ALEJANDRA PASCUAL, JAMES C. REGISTER, III, CHRISTOPHER J. SCELONGE, JOSHUA K. YOUNG, CATHY XIAOYAN ZHONG
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Patent number: 11512321Abstract: Compositions and methods are provided for the introduction and the regulated expression of genes in plants. Compositions include promoter constructs that provide a level of activity useful for the regulated expression of site-specific recombinases, while avoiding premature excision. Further provided are isolated polynucleotides encoding novel babyboom polypeptides, expression cassettes, and plants comprising the same. Methods for the introduction of genes into plants are provided, including methods for plastid transformation and methods for the transformation of tissues from mature seeds and leaves.Type: GrantFiled: February 22, 2021Date of Patent: November 29, 2022Inventors: William James Gordon-Kamm, Theodore M Klein, Keith S Lowe, Kevin E McBride, Christopher J Scelonge, Ning Wang
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Publication number: 20220251586Abstract: Compositions and methods are provided for stacking multiple independent transgenic loci into the genome of a plant. Compositions include plants, seeds or plant cells comprising at least one transgenic target site and at least one genomic locus of interest integrated at different genomic sites within a genomic window. Plant breeding techniques can be employed such that the transgenic target site and the genomic locus of interest can be bred together. In this way, multiple independent transgene integrations can be generated within a genomic window to create a complex trait locus. The complex trait locus is designed such that the transgenic target sites and/or genomic loci of interest can segregate independently of each other, thus providing the benefit of altering a complex trait locus by breeding-in and breeding-away specific elements. Various methods can also be employed to modify the target sites such that they contain a variety of polynucleotides of interest.Type: ApplicationFiled: March 21, 2022Publication date: August 11, 2022Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: SAVERIO CARL FALCO, MICHAEL LASSNER, ZHONGSEN LI, CHRISTOPHER J SCELONGE
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Patent number: 11312969Abstract: Compositions and methods are provided for stacking multiple independent transgenic loci into the genome of a plant. Compositions include plants, seeds or plant cells comprising at least one transgenic target site and at least one genomic locus of interest integrated at different genomic sites within a genomic window. Plant breeding techniques can be employed such that the transgenic target site and the genomic locus of interest can be bred together. In this way, multiple independent transgene integrations can be generated within a genomic window to create a complex trait locus. The complex trait locus is designed such that the transgenic target sites and/or genomic loci of interest can segregate independently of each other, thus providing the benefit of altering a complex trait locus by breeding-in and breeding-away specific elements. Various methods can also be employed to modify the target sites such that they contain a variety of polynucleotides of interest.Type: GrantFiled: August 26, 2019Date of Patent: April 26, 2022Inventors: Saverio Carl Falco, Michael Lassner, Zhongsen Li, Christopher J Scelonge
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Publication number: 20220002821Abstract: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.Type: ApplicationFiled: September 9, 2021Publication date: January 6, 2022Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: SCOTT DIEHN, ALBERT L LU, TIMOTHY M NOWATZKI, DOUGLAS S NUBEL, M ALEJANDRA PASCUAL, JAMES C REGISTER, III, CHRISTOPHER J SCELONGE, JOSHUA K YOUNG, CATHY XIAOYAN ZHONG, ERIN L CROWGEY
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Patent number: 11155883Abstract: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.Type: GrantFiled: January 14, 2019Date of Patent: October 26, 2021Inventors: Scott Diehn, Albert L Lu, Timothy M Nowatzki, Douglas S Nubel, M Alejandra Pascual, James C Register, III, Christopher J Scelonge, Joshua K Young, Cathy Xiaoyan Zhong, Erin L Crowgey
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Publication number: 20210180077Abstract: Compositions and methods are provided for the introduction and the regulated expression of genes in plants. Compositions include promoter constructs that provide a level of activity useful for the regulated expression of site-specific recombinases, while avoiding premature excision. Further provided are isolated polynucleotides encoding novel babyboom polypeptides, expression cassettes, and plants comprising the same. Methods for the introduction of genes into plants are provided, including methods for plastid transformation and methods for the transformation of tissues from mature seeds and leaves.Type: ApplicationFiled: February 22, 2021Publication date: June 17, 2021Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: WILLIAM JAMES GORDON-KAMM, THEODORE M KLEIN, KEITH S LOWE, KEVIN E MCBRIDE, CHRISTOPHER J SCELONGE, NING WANG
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Publication number: 20200385749Abstract: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.Type: ApplicationFiled: August 19, 2020Publication date: December 10, 2020Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: CLARA ALARCON, MATTHEW CURTIS HARMON, M. ALEJANDRA PASCUAL, JAMES C REGISTER, III, CHRISTOPHER J SCELONGE, JOSHUA K YOUNG, CATHY XIAOYAN ZHONG
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Publication number: 20200032281Abstract: A variety of methods and compostions are provided, including methods and compositions for targeted modification of a specific target site in a cell or organism, methods for integrating polynucleotides of interest, methods to assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, silence a gene, and identify and/or characterize transcriptional regulating regions. The methods involve the introduction of a cell proliferation factor and a double-strand break-inducing enzyme into an organism.Type: ApplicationFiled: August 14, 2019Publication date: January 30, 2020Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: WILLIAM JAMES GORDON-KAMM, KEITH S. LOWE, DAVID J. PETERSON, CHRISTOPHER J. SCELONGE, GRACE M. ST CLAIR, BING-BING WANG
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Publication number: 20190376073Abstract: Compositions and methods are provided for stacking multiple independent transgenic loci into the genome of a plant. Compositions include plants, seeds or plant cells comprising at least one transgenic target site and at least one genomic locus of interest integrated at different genomic sites within a genomic window. Plant breeding techniques can be employed such that the transgenic target site and the genomic locus of interest can be bred together. In this way, multiple independent transgene integrations can be generated within a genomic window to create a complex trait locus. The complex trait locus is designed such that the transgenic target sites and/or genomic loci of interest can segregate independently of each other, thus providing the benefit of altering a complex trait locus by breeding-in and breeding-away specific elements. Various methods can also be employed to modify the target sites such that they contain a variety of polynucleotides of interest.Type: ApplicationFiled: August 26, 2019Publication date: December 12, 2019Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: SAVERIO CARL FALCO, MICHAEL LASSNER, ZHONGSEN LI, CHRISTOPHER J SCELONGE
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Publication number: 20190338300Abstract: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.Type: ApplicationFiled: July 19, 2019Publication date: November 7, 2019Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: CLARA ALARCON, MATTHEW CURTIS HARMON, M. ALEJANDRA PASCUAL, JAMES C. REGISTER, III, CHRISTOPHER J SCELONGE, JOSHUA K. YOUNG, CATHY XIAOYAN ZHONG
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Patent number: 10443064Abstract: A variety of methods and compositions are provided, including methods and compositions for targeted modification of a specific target site in a cell or organism, methods for integrating polynucleotides of interest, methods to assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, silence a gene, and identify and/or characterize transcriptional regulating regions. The methods involve the introduction of a cell proliferation factor and a double-strand break-inducing enzyme into an organism.Type: GrantFiled: February 7, 2018Date of Patent: October 15, 2019Assignee: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: William J. Gordon-Kamm, Keith S. Lowe, David J. Peterson, Christopher J. Scelonge, Grace M. St. Clair, Bing-Bing Wang
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Patent number: 10407688Abstract: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.Type: GrantFiled: July 12, 2017Date of Patent: September 10, 2019Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E I DU PONT DE NEMOURS AND COMPANYInventors: Clara Maria Alarcon, Matthew C. Harmon, M. Alejandra Pascual, James C. Register, III, Christopher J. Scelonge, Joshua K. Young, Cathy Xiaoyan Zhong
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Publication number: 20190136331Abstract: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.Type: ApplicationFiled: January 14, 2019Publication date: May 9, 2019Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E.I. DU PONT DE NEMOURS AND COMPANYInventors: Scott Diehn, Albert L Lu, Timothy M Nowatzki, Douglas S Nubel, M Alejandra Pascual, James C Register, III, Christopher J Scelonge, Joshua K Young, Cathy Xiaoyan Zhong, Erin L Crowgey
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Patent number: 10190179Abstract: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.Type: GrantFiled: September 15, 2017Date of Patent: January 29, 2019Assignees: PIONEER HI-BRED INTERNATIONAL, INC., E I DU PONT DE NEMOURS AND COMPANYInventors: Scott Diehn, Albert L. Lu, Timothy M. Nowatzki, Douglas S. Nubel, M. Alejandra Pascual, James C. Register, III, Christopher J. Scelonge, Joshua K. Young, Cathy Xiaoyan Zhong, Erin L. Crowgey
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Publication number: 20180171346Abstract: A variety of methods and compositions are provided, including methods and compositions for targeted modification of a specific target site in a cell or organism, methods for integrating polynucleotides of interest, methods to assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, silence a gene, and identify and/or characterize transcriptional regulating regions. The methods involve the introduction of a cell proliferation factor and a double-strand break-inducing enzyme into an organism.Type: ApplicationFiled: February 7, 2018Publication date: June 21, 2018Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: WILLIAM J. GORDON-KAMM, KEITH S. LOWE, DAVID J. PETERSON, CHRISTOPHER J. SCELONGE, GRACE M. ST. CLAIR, BING-BING WANG
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Publication number: 20180023148Abstract: The invention provides DNA compositions that relate to transgenic insect resistant maize plants. Also provided are assays for detecting the presence of the maize DP-004114-3 event based on the DNA sequence of the recombinant construct inserted into the maize genome and the DNA sequences flanking the insertion site. Kits and conditions useful in conducting the assays are provided.Type: ApplicationFiled: September 15, 2017Publication date: January 25, 2018Applicants: PIONEER HI-BRED INTERNATIONAL, INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: SCOTT DIEHN, ALBERT L. LU, TIMOTHY M. NOWATZKI, DOUGLAS S. NUBEL, M. ALEJANDRA PASCUAL, JAMES C. REGISTER, III, CHRISTOPHER J. SCELONGE, JOSHUA K. YOUNG, CATHY XIAOYAN ZHONG, ERIN L. CROWGEY