Abstract: Compounds of Formula (I): wherein R1, R3, R11, R12, X, Y1, Y2, Y3, Y4 and are as defined in the description. Medicinal products containing the same which are useful in treating conditions requiring anti-apoptotic inhibitors.

Abstract: In combination a spouted pouch to be filled with a flowable product by a filling machine, a plug, and a cap. The interference fit plug is releasably mounted over the top end of the neck of the spout body and hermetically seals the product passage of the spout body. The plug is adapted to be removed by the filling machine and to be replaced by pressing the plug onto the neck after filling of the pouch. The plug removal, filling, and replacing of the plug are preferably performed in an aseptic environment. The cap is after the filling of the pouch and the replacing of the plug onto the neck. The capping is preferably performed by a capping machine in a non-aseptic environment.

Abstract: In combination a spouted pouch to be filled with a flowable product by a filling machine, a plug, and a cap. The interference fit plug is releasably mounted over the top end of the neck of the spout body and hermetically seals the product passage of the spout body. The plug is adapted to be removed by the filling machine and to be replaced by pressing the plug onto the neck after filling of the pouch. The plug removal, filling, and replacing of the plug are preferably performed in an aseptic environment. The cap is after the filling of the pouch and the replacing of the plug onto the neck. The capping is preferably performed by a capping machine in a non-aseptic environment.

Abstract: In combination a spouted pouch (1) to be filled with a flowable product by a filling machine, a plug (50), and a cap (70). The interference fit plug is releasably mounted over the top end of the neck of the spout body and hermetically seals the product passage of the spout body. The plug is adapted to be removed by the filling machine and to be replaced by pressing the plug onto the neck after filling of the pouch. The plug removal, filling, and replacing of the plug are preferably performed in an aseptic environment. The cap is after the filling of the pouch and the replacing of the plug onto the neck. The capping is preferably performed by a capping machine in a non-aseptic environment.

Abstract: In combination a spouted pouch (1) to be filled with a flowable product by a filling machine, a plug (50), and a cap (70). The interference fit plug is releasably mounted over the top end of the neck of the spout body and hermetically seals the product passage of the spout body. The plug is adapted to be removed by the filling machine and to be replaced by pressing the plug onto the neck after filling of the pouch. The plug removal, filling, and replacing of the plug are preferably performed in an aseptic environment. The cap is after the filling of the pouch and the replacing of the plug onto the neck. The capping is preferably performed by a capping machine in a non-aseptic environment.

Abstract: Liquid dispensing tap 1 connectable to a liquid container 70, e.g. a bag in box, for controlled dispensing of a liquid therefrom. The tap comprises a housing 10 forming an inlet of the tap and comprising a dispensing chamber wall portion 13 delimiting a dispensing chamber 14 with a valve seat 16 at an axial end and forming a lateral dispensing outlet 17 in communication with the dispensing chamber 14. The tap 1 comprises a plunger 30 with a stem 31 and a valve portion 32, the stem having an actuator engagement portion 33 outside said dispensing chamber and extending along an axis 15 through a bore 18 in the dispensing chamber wall portion and through the dispensing chamber. The plunger moves axially between a closed and an open position. A manually operable plunger actuator 50 engages said engagement portion of the stem to open the tap.

Abstract: A cassette for a waste disposal device is provided having a length of tubular liner film. The cassette has a central passage. The cassette has a forward edge, an aft edge, a first edge and a second edge defining a shape and a widthwise axis and a depthwise axis. The depthwise axis and widthwise axis intersect form two segments of each axis.

Abstract: Liquid dispensing tap 1 connectable to a liquid container 70, e.g. a bag in box, for controlled dispensing of a liquid therefrom. The tap comprises a housing 10 forming an inlet of the tap and comprising a dispensing chamber wall portion 13 delimiting a dispensing chamber 14 with a valve seat 16 at an axial end and forming a lateral dispensing outlet 17 in communication with the dispensing chamber 14. The tap 1 comprises a plunger 30 with a stem 31 and a valve portion 32, the stem having an actuator engagement portion 33 outside said dispensing chamber and extending along an axis 15 through a bore 18 in the dispensing chamber wall portion and through the dispensing chamber. The plunger moves axially between a closed and an open position. A manually operable plunger actuator 50 engages said engagement portion of the stem to open the tap.

Abstract: Liquid dispensing tap 1 connectable to a liquid container 70, e.g. a bag in box, for controlled dispensing of a liquid therefrom. The tap includes a housing 10 forming an inlet of the tap and including a dispensing chamber wall portion 13 delimiting a dispensing chamber 14 with a valve seat 15 at an axial end and forming a dispensing outlet 17 in communication with the dispensing chamber 14. The tap 1 includes a plunger 30 with a stem 31 and a valve portion 32. The stem having an actuator engagement portion 33 outside the dispensing chamber and extending along an axis 15 through a bore 18 in the dispensing chamber wall portion and throughout the dispensing chamber. The plunger moves axially between a closed and an open position. A manually operable plunger actuator 50 engages the engagement portion of the stem to open the tap.