Patents by Inventor Christopher K. Tompkins

Christopher K. Tompkins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Recombinant Production of Polyanionic Polymers, and Uses Thereof
    Publication number: 20080176288
    Abstract: A polyanionic polymer can improve the bioactivity and water-solubility properties of a drug to which it is joined. The inventive method provides a monodispersed preparation of a recombinantly-produced polyanionic polymer that can be easily manipulated, such as lengthened. An active moiety may be chemically or recombinantly joined to a polyanionic polymer to increase its biological half-life and/or solubility. The instant invention also provides a method for targeting the delivery of a polyanionic polymer conjugate or fusion protein to a specific cell type or tissue.
    Type: Application
    Filed: October 30, 2007
    Publication date: July 24, 2008
    Inventors: David W. Leung, Philip A. Bergman, Alan Lofquist, Gregory E. Pietz, Christopher K. Tompkins, David W. Waggoner
  • Human phosphatidic acid phosphatase
    Patent number: 7135314
    Abstract: This invention relates to a biotechnology invention concerning human phosphatidic acid phosphatase. More particularly, this invention relates to three variants of human phosphatidic acid phosphatase namely PAP-?(1 and 2), PAP-? and PAP-? and uses thereof.
    Type: Grant
    Filed: April 17, 1997
    Date of Patent: November 14, 2006
    Assignee: Cell Therapeutics, Inc.
    Inventors: David W. Leung, Christopher K. Tompkins
  • Recombinant production of polyanionic polymers and uses thereof
    Publication number: 20020169125
    Abstract: A polyanionic polymer can improve the bioactivity and water-solubility properties of a drug to which it is joined. The inventive method provides a monodispersed preparation of a recombinantly-produced polyanionic polymer that can be easily manipulated, such as lengthened. An active moiety may be chemically or recombinantly joined to a polyanionic polymer to increase its biological half-life and/or solubility. The instant invention also provides a method for targeting the delivery of a polyanionic polymer conjugate or fusion protein to a specific cell type or tissue.
    Type: Application
    Filed: March 20, 2002
    Publication date: November 14, 2002
    Applicant: CELL THERAPEUTICS, INC.
    Inventors: David W. Leung, Philip A. Bergman, Alan Lofquist, Gregory E. Pietz, Christopher K. Tompkins, David W. Waggoner
  • Phosphatidylcholine phospholipase D
    Patent number: 6274363
    Abstract: Three new isoforms of phosphatidylcholine phospholipase D, hPLD2.1, hPLD2.2 and hPLD1.5, can be produced recombinantly and are useful for screening compounds, as drug candidates, for an ability to modify PCPLD activity.
    Type: Grant
    Filed: June 30, 1998
    Date of Patent: August 14, 2001
    Assignee: Cell Therapeutics, Inc.
    Inventors: David W. Leung, Christopher K. Tompkins
  • Mammalian lysophosphatidic acid acyltransferase
    Patent number: 6136964
    Abstract: There is disclosed cDNA sequences and polypeptides having the enzyme lysophosphatidic acid acyltransferase (LPAAT) activity. LPAAT is also known as 1-acyl sn-glycerol-3-phosphate acyltransferase.
    Type: Grant
    Filed: March 19, 1996
    Date of Patent: October 24, 2000
    Assignee: Cell Therapeutics, Inc.
    Inventors: David W. Leung, James W. West, Christopher K. Tompkins
  • Mammalian lysophosphatidic acid acyltransferase
    Patent number: 6060263
    Abstract: There is disclosed cDNA sequences and polypeptides having the enzyme lysophosphatidic acid acyltransferase (LPAAT) activity. LPAAT is also known as 1-acyl sn-glycerol-3-phosphate acyltransferase.
    Type: Grant
    Filed: September 21, 1999
    Date of Patent: May 9, 2000
    Assignee: Cell Therapeutics, Inc.
    Inventors: David W. Leung, James W. West, Christopher K. Tompkins
  • Human phosphatidylcholine phospholipase D
    Patent number: 5859222
    Abstract: Disclosed are human cDNA and polypeptides sequences having phosphatidylcholine phospholipase D (PCPLD).
    Type: Grant
    Filed: December 17, 1996
    Date of Patent: January 12, 1999
    Assignee: Cell Therapeutics, Inc.
    Inventors: David W. Leung, Christopher K. Tompkins