Patents by Inventor Christopher M. Yates

Christopher M. Yates has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Metalloenzyme inhibitor compounds
    Patent number: 11938134
    Abstract: Provided are compounds having HDAC6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by HDAC6.
    Type: Grant
    Filed: June 2, 2021
    Date of Patent: March 26, 2024
    Assignee: Eikonizo Therapeutics, Inc.
    Inventor: Christopher M. Yates
  • Metalloenzyme inhibitor compounds
    Patent number: 11919883
    Abstract: Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: August 31, 2021
    Date of Patent: March 5, 2024
    Assignee: Ji Xing Pharmaceuticals Hong Kong Limited
    Inventors: Steven Sparks, Christopher M. Yates, Sammy R. Shaver
  • METALLOENZYME INHIBITOR COMPOUNDS
    Publication number: 20220088018
    Abstract: Provided are compounds having HDAC6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by HDAC6.
    Type: Application
    Filed: June 2, 2021
    Publication date: March 24, 2022
    Applicant: Eikonizo Therapeutics, Inc.
    Inventor: Christopher M. Yates
  • METALLOENZYME INHIBITOR COMPOUNDS
    Publication number: 20220081420
    Abstract: Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Application
    Filed: January 8, 2020
    Publication date: March 17, 2022
    Inventors: Steven SPARKS, Christopher M. YATES
  • METALLOENZYME INHIBITOR COMPOUNDS
    Publication number: 20220009907
    Abstract: Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Application
    Filed: August 31, 2021
    Publication date: January 13, 2022
    Inventors: Steven SPARKS, Christopher M. YATES, Sammy R. SHAVER
  • ANTIFUNGAL COMPOUNDS
    Publication number: 20210360921
    Abstract: The present invention relates to compounds of Formula (I): wherein R1 is as defined herein, or an acceptable salt, solvate, prodrug or hydrate thereof. The compounds of Formula I are inhibitors of metalloenzymes, such as lanosterol demethylase (CYP51).
    Type: Application
    Filed: June 3, 2021
    Publication date: November 25, 2021
    Applicant: Mycovia Pharmaceuticals, Inc.
    Inventors: William J. Hoekstra, Christopher M. Yates, Robert J. Schotzinger, Michael R. Loso, Gary D. Gustafson, Michael T. Sullenberger, Kimberly Steward, Javier Delgado, Xuelin Wang
  • METALLOENZYME INHIBITOR COMPOUNDS
    Publication number: 20210322409
    Abstract: Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Application
    Filed: June 17, 2021
    Publication date: October 21, 2021
    Inventors: Steven SPARKS, Christopher M. YATES, Sammy R. SHAVER, William J. HOEKSTRA
  • Metalloenzyme inhibitor compounds
    Patent number: 11136309
    Abstract: Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: January 17, 2020
    Date of Patent: October 5, 2021
    Assignee: PHASEBIO PHARMACEUTICALS, INC.
    Inventors: Steven Sparks, Christopher M. Yates, Sammy R. Shaver
  • Antifungal compounds
    Patent number: 11051514
    Abstract: The present invention relates to compounds of Formula (I): wherein R1 is as defined herein, or an acceptable salt, solvate, prodrug or hydrate thereof. The compounds of Formula I are inhibitors of metalloenzymes, such as lanosterol demethylase (CYP51).
    Type: Grant
    Filed: May 17, 2016
    Date of Patent: July 6, 2021
    Assignee: Mycovia Pharmaceuticals, Inc.
    Inventors: William J. Hoekstra, Christopher M. Yates, Robert J. Schotzinger, Michael R. Loso, Gary D. Gustafson, Michael T. Sullenberger, Kimberly Steward, Javier Delgado, Xuelin Wang
  • Metalloenzyme inhibitor compounds
    Patent number: 11040034
    Abstract: Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: September 7, 2018
    Date of Patent: June 22, 2021
    Assignee: PHASEBIO PHARMACEUTICALS, INC.
    Inventors: Steven Sparks, Christopher M. Yates, Sammy R. Shaver, William J. Hoekstra
  • Metalloenzyme inhibitor compounds
    Patent number: 10919874
    Abstract: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders, or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: February 16, 2021
    Assignee: NQP 1598, LTD.
    Inventors: William J. Hoekstra, Christopher M. Yates
  • METALLOENZYME INHIBITOR COMPOUNDS
    Publication number: 20200392112
    Abstract: Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Application
    Filed: January 17, 2020
    Publication date: December 17, 2020
    Inventors: Steven Sparks, Christopher M. Yates, Sammy R. Shaver
  • Antifungal compound process
    Patent number: 10836740
    Abstract: The present invention relates to a process for preparing a compound of 5 or 5*, or a mixture thereof, that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compounds 7 or 7* and 11 or 11* and substituted derivatives thereof.
    Type: Grant
    Filed: July 1, 2019
    Date of Patent: November 17, 2020
    Assignee: MYCOVIA PHARMACEUTICALS, INC.
    Inventors: David Dale Wirth, Christopher M. Yates, William J. Hoekstra, Martin F. Bindl, Eduard Hartmann
  • Antifungal compound process
    Patent number: 10745378
    Abstract: The present invention relates to a process for preparing compound 1 that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compound 1 and substituted derivatives thereof.
    Type: Grant
    Filed: January 22, 2019
    Date of Patent: August 18, 2020
    Assignee: Mycovia Pharmaceuticals, Inc.
    Inventors: William J. Hoekstra, Christopher M. Yates
  • METALLOENZYME INHIBITOR COMPOUNDS
    Publication number: 20200171028
    Abstract: Provided are compounds having HDAC6 modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by HDAC6.
    Type: Application
    Filed: July 22, 2019
    Publication date: June 4, 2020
    Inventor: Christopher M. Yates
  • ANTIFUNGAL COMPOUND PROCESS
    Publication number: 20200024252
    Abstract: The present invention relates to a process for preparing a compound of 5 or 5*, or a mixture thereof, that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compounds 7 or 7* and 11 or 11* and substituted derivatives thereof.
    Type: Application
    Filed: July 1, 2019
    Publication date: January 23, 2020
    Inventors: David Dale WIRTH, Christopher M. YATES, William J. HOEKSTRA, Martin F. BINDL, Eduard HARTMANN
  • Metalloenzyme inhibitor compounds
    Patent number: 10538511
    Abstract: Provided are compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders or symptoms thereof mediated by such metalloenzymes.
    Type: Grant
    Filed: December 29, 2017
    Date of Patent: January 21, 2020
    Assignee: Selenity Therapeutics (Bermuda), Ltd.
    Inventors: Steven Sparks, Christopher M. Yates, Sammy R. Shaver
  • Antifungal compound process
    Patent number: 10513505
    Abstract: The present invention relates to a process for preparing a compound of 5 or 5*, or a mixture thereof, and/or a compound of 14 or 14*, or a mixture thereof, that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compounds 7, 7* and 11, 11* and substituted derivatives thereof.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: December 24, 2019
    Assignee: NQP 1598, LTD.
    Inventors: David Dale Wirth, Christopher M. Yates, William J. Hoekstra
  • METALLOENZYME INHIBITOR COMPOUNDS
    Publication number: 20190382370
    Abstract: The instant invention describes compounds having metalloenzyme modulating activity, and methods of treating diseases, disorders, or symptoms thereof mediated by such metalloenzymes.
    Type: Application
    Filed: July 31, 2019
    Publication date: December 19, 2019
    Inventors: William J. Hoekstra, Christopher M. Yates
  • Antifungal compound process
    Patent number: 10464921
    Abstract: The present invention relates to a process for preparing a compound of 5 or 5*, or a mixture thereof, that is useful as an antifungal agent. In particular, the invention seeks to provide new methodology for preparing compounds 7, 7* and 11, 11* and substituted derivatives thereof.
    Type: Grant
    Filed: September 16, 2016
    Date of Patent: November 5, 2019
    Assignee: Mycovia Pharmaceuticals, Inc.
    Inventors: David Dale Wirth, Christopher M. Yates, William J. Hoekstra, Martin F. Bindl, Eduard Hartmann