Patents by Inventor Christopher Novotny

Christopher Novotny has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TREATMENT OF LAG-3 POSITIVE TUMORS
    Publication number: 20240092911
    Abstract: The invention provides a method of treating a tumor in a human patient comprising (i) identifying a patient as having a LAG-3 positive tumor and (ii) administering to the patient a PD-1 pathway inhibitor, a combination of a PD1 pathway inhibitor and an immune checkpoint inhibitor, a combination of a LAG-3 inhibitor and a PD-1 pathway inhibitor, or an anti-CTLA4 antibody. In some embodiments, the method further comprises identifying the patient as having a LAG-3 positive PD-L1 positive tumor. In some embodiments, the LAG-3 inhibitor is an anti-LAG-3 antibody and the PD-1 pathway inhibitor is an anti-PD-1 antibody. The methods of the invention can improve response rates to treatment with a PD-1 pathway inhibitor, a combination of a PD1 pathway inhibitor and an immune checkpoint inhibitor, or a combination of a LAG-3 inhibitor and a PD-1 pathway inhibitor.
    Type: Application
    Filed: August 18, 2023
    Publication date: March 21, 2024
    Applicant: Bristol-Myers Squibb Company
    Inventors: James NOVOTNY, Nils LONBERG, Cyrus HEDVAT, Raphael CLYNES, Darren LOCKE, John P. COGSWELL, Jeffrey JACKSON, Christopher HARBISON, Robin EDWARDS
  • HER3 ligands and uses thereof
    Patent number: 11124483
    Abstract: Described herein, inter alia, are compositions of HER3 ligands and methods for treating diseases using the same.
    Type: Grant
    Filed: September 2, 2016
    Date of Patent: September 21, 2021
    Assignee: The Regents of the University of California
    Inventors: Christopher Novotny, Kevan Shokat, Natalia Jura
  • HER3 LIGANDS AND USES THEREOF
    Publication number: 20200223799
    Abstract: Described herein, inter alia, are compositions of HER3 ligands and methods for treating diseases using the same.
    Type: Application
    Filed: September 2, 2016
    Publication date: July 16, 2020
    Inventors: Christopher Novotny, Kevan SHOKAT, Natalia JURA
  • ErbB Inhibitors and Uses Thereof
    Publication number: 20190119284
    Abstract: Described herein, inter alia, are compositions of ErbB modulators and methods of using the same.
    Type: Application
    Filed: April 19, 2017
    Publication date: April 25, 2019
    Inventors: Christopher Novotny, Kevan M. Shokat, Weijun Shen