Abstract: Disclosed herein are methods and processes of preparing vadadustat and pharmaceutically acceptable salts thereof, and intermediates of formula (I) and their salts useful for the synthesis of vadadustat.

Abstract: A sodium-cooled nuclear reactor includes at least one electromagnetic pump assembly and a backflow reduction pipe. The backflow reduction pipe may include an inlet, an outlet, at least one tubular section having a first length and a first diameter, and at least one fluid diode section between the inlet and the outlet.

Abstract: Computer implemented systems and methods are disclosed for importing data from electronic data files. In accordance with some embodiments, a file format is assigned to a source electronic data files by a data importation system. The data importation system may further identify a file type identifier associated with the source electronic data file and map the source electronic data file to a transformation template. The data importation system may further store the file format, file type identifier, and an indication of the transformation template as a file type profile associated with the source electronic data file in a database.

Abstract: The method includes configuring a nuclear reactor to at least partially mitigate liquid metal coolant backflow in the nuclear reactor in response to an at least partial failure of a primary electromagnetic pump (EMP) within a reactor pressure vessel of the nuclear reactor, the nuclear reactor being liquid metal-cooled, the primary EMP configured to circulate liquid metal coolant through at least a reactor core of the nuclear reactor, the configuring including, installing a backflow EMP within the reactor pressure vessel, such that when selectively activated, the backflow EMP at least partially mitigates liquid metal coolant backflow through the primary EMP.

Abstract: Estimating the ego-motion of a vehicle, e.g., the self-motion of the vehicle, can be improved by pre-processing data from two or more radars onboard the vehicle using a processor common to the two or more radars. The common processor can pre-process the data using a velocity vector processing technique that can estimate a velocity vector at each point of a predefined number of points, such as arranged in a grid in the field-of-view of radars, with coordinates (X, Y, Z (optional)), where U is the component of the velocity in the X-direction, V is the component of the velocity in the Y-direction, and W is the component of the velocity in the optional Z-direction.

Abstract: The method includes configuring a nuclear reactor to at least partially mitigate liquid metal coolant backflow in the nuclear reactor in response to an at least partial failure of a primary electromagnetic pump (EMP) within a reactor pressure vessel of the nuclear reactor, the nuclear reactor being liquid metal-cooled, the primary EMP configured to circulate liquid metal coolant through at least a reactor core of the nuclear reactor, the configuring including, installing a backflow EMP within the reactor pressure vessel, such that when selectively activated, the backflow EMP at least partially mitigates liquid metal coolant backflow through the primary EMP.

Abstract: Navigation systems and methods for autonomous vehicles are provided. The navigation system may include multiple navigation subsystems, including one having an inertial measurement unit (IMU). That unit may serve as the primary unit for navigation purposes, with other navigation subsystems being treated as secondary. The other navigation subsystems may include global positioning system (GPS) sensors, and perception sensors. In some embodiments, the navigation system may include a first filter for the IMU sensor and separate filters for the other navigation subsystems.

Abstract: A liquid metal-cooled nuclear reactor includes, within a reactor pressure vessel, a primary electromagnetic pump (EMP) circulating liquid metal coolant through the reactor core and a backflow EMP. The nuclear reactor may be configured to at least partially mitigate liquid metal coolant backflow in response to a primary EMP failure. The backflow EMP is coupled in series with the primary EMP within the reactor pressure vessel. The backflow EMP may be selectively activated in response to failure of the primary EMP to mitigate liquid metal backflow through the primary EMP. The primary EMP and backflow EMP may receive power from separate power sources. Multiple backflow EMPs may be coupled in parallel to the primary EMP via parallel liquid metal coolant lines. A nuclear reactor may include multiple primary EMPs and multiple sets of backflow EMPs, where each separate set of backflow EMPs is coupled to a separate primary EMP.

Abstract: A sodium-cooled nuclear reactor includes at least one electromagnetic pump assembly and a backflow reduction pipe. The backflow reduction pipe may include an inlet, an outlet, at least one tubular section having a first length and a first diameter, and at least one fluid diode section between the inlet and the outlet.

Abstract: A sodium-cooled nuclear reactor includes at least one electromagnetic pump assembly and a backflow reduction pipe. The backflow reduction pipe may include an inlet, an outlet, at least one tubular section having a first length and a first diameter, and at least one fluid diode section between the inlet and the outlet.

Abstract: A sodium-cooled nuclear reactor includes at least one electromagnetic pump assembly and a backflow reduction pipe. The backflow reduction pipe may include an inlet, an outlet, at least one tubular section having a first length and a first diameter, and at least one fluid diode section between the inlet and the outlet.

Abstract: A liquid metal-cooled nuclear reactor includes, within a reactor pressure vessel, a primary electromagnetic pump (EMP) circulating liquid metal coolant through the reactor core and a backflow EMP. The nuclear reactor may be configured to at least partially mitigate liquid metal coolant backflow in response to a primary EMP failure. The backflow EMP is coupled in series with the primary EMP within the reactor pressure vessel. The backflow EMP may be selectively activated in response to failure of the primary EMP to mitigate liquid metal backflow through the primary EMP. The primary EMP and backflow EMP may receive power from separate power sources. Multiple backflow EMPs may be coupled in parallel to the primary EMP via parallel liquid metal coolant lines. A nuclear reactor may include multiple primary EMPs and multiple sets of backflow EMPs, where each separate set of backflow EMPs is coupled to a separate primary EMP.

Abstract: A sodium-cooled nuclear reactor includes at least one electromagnetic pump assembly and a backflow reduction pipe. The backflow reduction pipe may include an inlet, an outlet, at least one tubular section having a first length and a first diameter, and at least one fluid diode section between the inlet and the outlet.

Abstract: A system and method for predicting acoustic loads expected on a boiling water reactor (BWR) may include a BWR scale model, a test fixture for generating air flow in the scale model, and one or measurement devices for monitoring system behavior to predict how acoustic loads may affect plant operation for the BWR being evaluated.

Abstract: A method of predicting stresses on a BWR steam dryer that includes creating an analytical acoustic model of a BWR steam system; generating pressure estimations by inputting empirical data into the analytical acoustic model of the BWR steam system; creating an analytical structural model of the BWR steam dryer; and predicting stresses on the BWR steam dryer using the analytical structural model and the pressure estimations.

Abstract: A method of predicting stresses on a BWR steam dryer that includes creating an analytical acoustic model of a BWR steam system; generating pressure estimations by inputting empirical data into the analytical acoustic model of the BWR steam system; creating an analytical structural model of the BWR steam dryer; and predicting stresses on the BWR steam dryer using the analytical structural model and the pressure estimations.

Abstract: An electronic health care management system is provided which collects both subjective and objective information regarding a patient into a clinical patient record, and uses the record to determine evidence-based recommendations. A healthcare provider may decide to implement certain recommendations, and/or provide additional interventions which are collectively implemented using automated support tools. Often, a plan can include follow-up activities which may be automatically scheduled by the electronic health care management system, and may include external scheduling programs and corresponding application-programming interfaces (APIs).

Abstract: A filtering apparatus having a filter retrieval apparatus, an integrated jib, and a clamping assembly for providing a seal between a filter and a cabinet.

Abstract: Techniques are disclosed for systematically assessing an enterprise's security risks in view of a set of security patterns. Each pattern that is applicable to the enterprise's operation is then considered against the backdrop of a set of common attributes that are used, in turn, to further distinguish each pattern from a risk and security solution perspective. Using the disclosed techniques, specific security risks can be identified and appropriate security products can be selected to address those risks in a systematic manner, thereby assisting information technology decision makers across a wide variety of enterprises in deriving security solutions. These security solutions will typically be more effective and efficient from a functional perspective, as well as being more cost-effective, than security solutions created using prior art ad hoc approaches. The disclosed techniques may also be leveraged to create a requirements list for function to be included in a security product.

Abstract: Selective serotonin reuptake inhibitors useful in the treatment of non-cardiac chest pain or the treatment of symptoms of gastro-esophageal reflux disease.