Patents by Inventor Christopher Peter Youd

Christopher Peter Youd has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Modified enzymes
    Patent number: 11965183
    Abstract: The invention relates to modified Dda helicases which can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
    Type: Grant
    Filed: October 13, 2021
    Date of Patent: April 23, 2024
    Assignee: Oxford Nanopore Technologies PLC
    Inventors: Andrew John Heron, Rebecca Victoria Bowen, Mark Bruce, Lakmal Jayasinghe, Joseph Hargreaves Lloyd, Szabolcs Soeroes, Elizabeth Jayne Wallace, Christopher Peter Youd
  • METHOD
    Publication number: 20240076729
    Abstract: Provided herein is a method of characterising a target polynucleotide as it moves with respect to a nanopore using a motor protein. Also provided are polynucleotide adapters and kits comprising such adapters. The methods, kits and adapters find use in characterising polynucleotides, for example in sequencing.
    Type: Application
    Filed: June 18, 2021
    Publication date: March 7, 2024
    Applicant: Oxford Nanopore Technologies PLC
    Inventors: Rebecca Victoria Bowen, Clive Gavin Brown, Mark John Bruce, Daniel Ryan Garalde, James Edward Graham, Andrew John Heron, Etienne Raimondeau, James White, Christopher Peter Youd
  • METHOD
    Publication number: 20240060126
    Abstract: The invention relates to improving the movement of a target polynucleotide with respect to a transmembrane pore when the movement is controlled by a polynucleotide binding protein.
    Type: Application
    Filed: June 27, 2023
    Publication date: February 22, 2024
    Applicant: Oxford Nanopore Technologies PLC
    Inventors: Lakmal Nishantha Jayasinghe, Elizabeth Jayne Wallace, Jonathan Bankes Pugh, Richard George Hambley, Neil Roger Wood, Clive Gavin Brown, James White, Andrew John Heron, Mark John Bruce, Christopher Peter Youd, Rebecca Victoria Bowen
  • METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO A TARGET POLYNUCLEOTIDE
    Publication number: 20240026441
    Abstract: The invention relates to new methods of attaching one or more polynucleotide binding proteins to a target polynucleotide. The invention also related to new methods of characterising target polynucleotides.
    Type: Application
    Filed: June 23, 2023
    Publication date: January 25, 2024
    Applicant: Oxford Nanopre Technologies PLC
    Inventors: Andrew John Heron, Clive Gavin Brown, Rebecca Victoria Bowen, James White, Daniel John Turner, Joseph Hargreaves Lloyd, Christopher Peter Youd
  • A METHOD OF SELECTIVELY CHARACTERISING A POLYNUCLEOTIDE USING A DETECTOR
    Publication number: 20230295712
    Abstract: The invention provides a method of selectively characterising polynucleotides of a desired property, such as length, using a nanopore, based on the translocation of the polynucleotide through or across the nanopore. Kits and systems for use in such methods are also provided. The methods of the invention are particularly suitable for sequencing polynucleotides such as DNA.
    Type: Application
    Filed: June 18, 2021
    Publication date: September 21, 2023
    Applicant: Oxford Nanopore Technologies PLC
    Inventors: Rebecca Victoria Bowen, Clive Gavin Brown, Mark John Bruce, Daniel Ryan Garalde, James Edward Graham, Andrew John Heron, Etienne Raimondeau, James White, Christopher Peter Youd
  • Method of improving the movement of a target polynucleotide with respect to a transmembrane pore
    Patent number: 11739377
    Abstract: The invention relates to improving the movement of a target polynucleotide with respect to a transmembrane pore when the movement is controlled by a polynucleotide binding protein. The invention also relates to improved transmembrane pores and polynucleotide binding proteins.
    Type: Grant
    Filed: October 20, 2020
    Date of Patent: August 29, 2023
    Assignee: Oxford Nanopore Technologies PLC
    Inventors: Lakmal Nishantha Jayasinghe, Elizabeth Jayne Wallace, Jonathan Bankes Pugh, Richard George Hambley, Neil Roger Wood, Clive Gavin Brown, James White, Andrew John Heron, Mark Bruce, Christopher Peter Youd, Rebecca Victoria Bowen
  • Method for attaching one or more polynucleotide binding proteins to a target polynucleotide
    Patent number: 11725235
    Abstract: The invention relates to new methods of attaching one or more polynucleotide binding proteins to a target polynucleotide. The invention also related to new methods of characterising target polynucleotides.
    Type: Grant
    Filed: August 14, 2019
    Date of Patent: August 15, 2023
    Assignee: Oxford Nanopore Technologies PLC
    Inventors: Andrew John Heron, Clive Gavin Brown, Rebecca Victoria Bowen, James White, Daniel John Turner, Joseph Hargreaves Lloyd, Christopher Peter Youd
  • METHOD OF REPEATEDLY MOVING A DOUBLE-STRANDED POLYNUCLEOTIDE THROUGH A NANOPORE
    Publication number: 20230227902
    Abstract: Provided herein is a method of moving a double-stranded polynucleotide with respect to a nanopore using a motor protein. The method allows a portion of the polynucleotide to be interrogated by the pore multiple times. Also provided are polynucleotide adapters and kits comprising such adapters. The methods find use in characterising polynucleotides, for example in sequencing.
    Type: Application
    Filed: June 18, 2021
    Publication date: July 20, 2023
    Applicant: Oxford Nanopore Technologies PLC
    Inventors: James Edward Graham, Christopher Peter Youd, Clive Gavin Brown, Marion Louise Crawford, Andrew John Heron, James White
  • METHOD
    Publication number: 20230227903
    Abstract: Provided herein is a method of characterising a target polynucleotide as it moves with respect to a nanopore using a motor protein. Also provided are polynucleotide adapters and kits comprising such adapters. The methods, kits and adapters find use in characterising polynucleotides, for example in sequencing.
    Type: Application
    Filed: June 18, 2021
    Publication date: July 20, 2023
    Applicant: Oxford Nanopore Technologies PLC
    Inventors: Rebecca Victoria Bowen, Clive Gavin Brown, Mark John Bruce, Daniel Ryan Garalde, James Edward Graham, Andrew John Heron, Etienne Raimondeau, James White, Christopher Peter Youd
  • MODIFIED ENZYMES
    Publication number: 20220135956
    Abstract: The invention relates to modified Dda helicases which can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
    Type: Application
    Filed: October 13, 2021
    Publication date: May 5, 2022
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Andrew John Heron, Rebecca Victoria Bowen, Mark Bruce, Lakmal Jayasinghe, Joseph Hargreaves Lloyd, Szabolcs Soeroes, Elizabeth Jayne Wallace, Christopher Peter Youd
  • Modified enzymes
    Patent number: 11180741
    Abstract: The invention relates to modified Dda helicases which can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
    Type: Grant
    Filed: October 6, 2015
    Date of Patent: November 23, 2021
    Assignee: Oxford Nanopore Technologies Ltd.
    Inventors: Andrew John Heron, Rebecca Victoria Bowen, Mark Bruce, Lakmal Jayasinghe, Joseph Hargreaves Lloyd, Szabolcs Soeroes, Elizabeth Jayne Wallace, Christopher Peter Youd
  • METHOD OF IMPROVING THE MOVEMENT OF A TARGET POLYNUCLEOTIDE WITH RESPECT TO A TRANSMEMBRANE PORE
    Publication number: 20210139972
    Abstract: The invention relates to improving the movement of a target polynucleotide with respect to a transmembrane pore when the movement is controlled by a polynucleotide binding protein.
    Type: Application
    Filed: October 20, 2020
    Publication date: May 13, 2021
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Lakmal Jayasinghe, Elizabeth Jayne Wallace, Jonathan Bankes Pugh, Richard George Hambley, Neil Roger Wood, Clive Gavin Brown, James White, Andrew John Heron, Mark Bruce, Christopher Peter Youd, Rebecca Victoria Bowen
  • Method of improving the movement of a target polynucleotide with respect to a transmembrane pore
    Patent number: 10844432
    Abstract: The invention relates to improving the movement of a target polynucleotide with respect to a transmembrane pore when the movement is controlled by a polynucleotide binding protein. The invention also relates to improved transmembrane pores and polynucleotide binding proteins.
    Type: Grant
    Filed: September 17, 2019
    Date of Patent: November 24, 2020
    Assignee: Oxford Nanopore Technologies, Ltd.
    Inventors: Lakmal Jayasinghe, Elizabeth Jayne Wallace, Jonathan Bankes Pugh, Richard George Hambley, Neil Roger Wood, Clive Gavin Brown, James White, Andrew John Heron, Mark John Bruce, Christopher Peter Youd, Rebecca Victoria Bowen
  • METHOD OF IMPROVING THE MOVEMENT OF A TARGET POLYNUCLEOTIDE WITH RESPECT TO A TRANSMEMBRANE PORE
    Publication number: 20200224262
    Abstract: The invention relates to improving the movement of a target polynucleotide with respect to a transmembrane pore when the movement is controlled by a polynucleotide binding protein.
    Type: Application
    Filed: September 17, 2019
    Publication date: July 16, 2020
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Lakmal Jayasinghe, Elizabeth Jayne Wallace, Jonathan Bankes Pugh, Richard George Hambley, Neil Roger Wood, Clive Gavin Brown, James White, Andrew John Heron, Mark John Bruce, Christopher Peter Youd, Rebecca Victoria Bowen
  • METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO A TARGET POLYNUCLEOTIDE
    Publication number: 20200087724
    Abstract: The invention relates to new methods of attaching one or more polynucleotide binding proteins to a target polynucleotide. The invention also related to new methods of characterising target polynucleotides.
    Type: Application
    Filed: August 14, 2019
    Publication date: March 19, 2020
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Andrew John Heron, Clive Gavin Brown, Rebecca Victoria Bowen, James White, Daniel John Turner, Joseph Hargreaves Lloyd, Christopher Peter Youd
  • Method of improving the movement of a target polynucleotide with respect to a transmembrane pore
    Patent number: 10443097
    Abstract: The invention relates to improving the movement of a target polynucleotide with respect to a transmembrane pore when the movement is controlled by a polynucleotide binding protein. The invention also relates to improved transmembrane pores and polynucleotide binding proteins.
    Type: Grant
    Filed: May 1, 2015
    Date of Patent: October 15, 2019
    Assignee: Oxford Nanopore Technologies Ltd.
    Inventors: Lakmal Jayasinghe, Elizabeth Jayne Wallace, Jonathan Bankes Pugh, Richard George Hambley, Neil Roger Wood, Clive Gavin Brown, James White, Andrew John Heron, Mark John Bruce, Christopher Peter Youd, Rebecca Victoria Bowen
  • Method for attaching one or more polynucleotide binding proteins to a target polynucleotide
    Patent number: 10385389
    Abstract: The invention relates to new methods of attaching one or more polynucleotide binding proteins to a target polynucleotide. The invention also relates to new methods of characterizing target polynucleotides.
    Type: Grant
    Filed: January 22, 2015
    Date of Patent: August 20, 2019
    Assignee: Oxford Nanopore Technologies Ltd.
    Inventors: Andrew John Heron, Clive Gavin Brown, Rebecca Victoria Bowen, James White, Daniel John Turner, Joseph Hargreaves Lloyd, Christopher Peter Youd
  • MODIFIED ENZYMES
    Publication number: 20180179500
    Abstract: The invention relates to modified Dda helicases which can be used to control the movement of polynucleotides and are particularly useful for sequencing polynucleotides.
    Type: Application
    Filed: October 6, 2015
    Publication date: June 28, 2018
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Andrew John Heron, Rebecca Victoria Bowen, Mark Bruce, Lakmal Jayasinghe, Joseph Hargreaves Lloyd, Szabolcs Soeroes, Elizabeth Jayne Wallace, Christopher Peter Youd
  • METHOD FOR ATTACHING ONE OR MORE POLYNUCLEOTIDE BINDING PROTEINS TO A TARGET POLYNUCLEOTIDE
    Publication number: 20170107569
    Abstract: The invention relates to new methods of attaching one or more polynucleotide binding proteins to a target polynucleotide. The invention also relates to new methods of characterising target polynucleotides.
    Type: Application
    Filed: January 22, 2015
    Publication date: April 20, 2017
    Applicant: Oxford Nanopore Technologies Ltd.
    Inventors: Andrew John Heron, Clive Gavin Brown, Rebecca Victoria Bowen, James White, Daniel John Turner, Joseph Hargreaves Lloyd, Christopher Peter Youd