Abstract: A catheter hub assembly. The catheter hub assembly includes a catheter hub body, a septum and a septum retainer, the catheter hub body having a distal end, a proximal and an internal wall defining an internal fluid passageway therebetween, the internal wall defining a transitional step within the internal fluid passageway, the septum positioned within the internal fluid passageway such that a distal end of the septum abuts up against the transitional step, the septum retainer at least partially receivable within the internal fluid passageway and having an outer wall shaped and sized to interlock with the inner wall of the catheter hub body, the outer wall including one or more lateral ribs configured to inhibit rotation of the septum retainer relative to the catheter hub body.

Abstract: Catheter assemblies may include introducer needles having a notch or similar structure that allows flashback blood to enter the annular space between a catheter tube and an introducer needle of an IV catheter. The presence of flashback blood in this annular space can provide a clinician with an early, visible indication that a needle has entered a vein. The notch, however, may create a leak path for blood to escape outside of the catheter assembly, unless contained. Disclosed herein is a notch containment that prevents the notch from providing a leak path for blood to escape outside of the catheter during or after needle withdrawal.

Abstract: A method of constructing a catheter assembly having an integrated septum. The method comprising molding a catheter hub having a distal end, a proximal end, and an internal wall defining an internal fluid passageway therebetween, the internal fluid wall defining an injection mold window located between the distal end and the proximal end; seating a catheter tube within the internal fluid passageway of the catheter hub, such that a proximal end of the catheter tube resides within the internal fluid passageway of the catheter hub, and a distal end of the catheter tube extends distally from the distal end of the catheter hub; plugging at least a proximal end of the catheter hub with a mold core shut off pin; and injection molding a septum in at least a portion of the internal fluid passageway between the mold core shut off pin and the proximal end of the catheter tube through the injection mold window.

Abstract: The present disclosure provides for a safety catheter assembly comprising a needle hub, a catheter hub, a tip protector housing. Various embodiments can comprise a push-off tab extending radially from the tip protector housing or a portion thereof, and/or structure can be added or removed to affect compliance between a catheter assembly and a catheter insertion device.

Abstract: A self activating vent cap configured to be operably coupled to a needleless connector and automatically shifted relative to the needleless connector from the first, storage position to a second, activated position upon rotation of the vent cap relative to the needleless connector. The self activating vent cap including a threaded portion, an activation portion and a biasing mechanism, wherein shifting of the activation portion to the second, activated position is selectively precluded by the interference of at least one ridge of the threaded portion with a ledge of the activation portion.

Abstract: The present disclosure provides for a safety catheter assembly comprising a needle hub, a catheter hub, a tip protector housing. Various embodiments can comprises a push-off tab extending radially from the tip protector housing or a portion thereof, and/or structure can be added or removed to affect compliance between a catheter assembly and a catheter insertion device.

Abstract: A safety catheter insertion assembly configured to inhibit access to the distal tip of a needle cannula prior to release of a catheter insertion assembly from a catheter hub. The safety catheter insertion assembly including a catheter assembly having an elastomeric blood control valve and a catheter insertion device having a safety clip, the safety clip movable between an expanded configuration in which a portion of the safety clip applies a compressive force to a portion of the elastomeric blood control valve, and a collapsed configuration in which the compressive force is reduced and release of the safety clip from the elastomeric blood control valve is enabled.

Abstract: A catheter hub assembly. The catheter hub assembly includes a catheter hub body, a septum and a septum retainer, the catheter hub body having a distal end, a proximal and an internal wall defining an internal fluid passageway therebetween, the internal wall defining a transitional step within the internal fluid passageway, the septum positioned within the internal fluid passageway such that a distal end of the septum abuts up against the transitional step, the septum retainer at least partially receivable within the internal fluid passageway and having an outer wall shaped and sized to interlock with the inner wall of the catheter hub body, the outer wall including one or more lateral ribs configured to inhibit rotation of the septum retainer relative to the catheter hub body.

Abstract: The present disclosure provides for a safety catheter assembly comprising a needle hub, a catheter hub, a tip protector housing. Various embodiments can comprises a push-off tab extending radially from the tip protector housing or a portion thereof, and/or structure can be added or removed to affect compliance between a catheter assembly and a catheter insertion device.

Abstract: A catheter hub assembly. The catheter hub assembly includes a catheter hub body, a septum and a septum retainer, the catheter hub body having a distal end, a proximal and an internal wall defining an internal fluid passageway therebetween, the internal wall defining a transitional step within the internal fluid passageway, the septum positioned within the internal fluid passageway such that a distal end of the septum abuts up against the transitional step, the septum retainer at least partially receivable within the internal fluid passageway and having an outer wall shaped and sized to interlock with the inner wall of the catheter hub body, the outer wall including one or more lateral ribs configured to inhibit rotation of the septum retainer relative to the catheter hub body.

Abstract: A method of constructing a catheter assembly having an integrated septum. The method comprising molding a catheter hub having a distal end, a proximal end, and an internal wall defining an internal fluid passageway therebetween, the internal fluid wall defining an injection mold window located between the distal end and the proximal end; seating a catheter tube within the internal fluid passageway of the catheter hub, such that a proximal end of the catheter tube resides within the internal fluid passageway of the catheter hub, and a distal end of the catheter tube extends distally from the distal end of the catheter hub; plugging at least a proximal end of the catheter hub with a mold core shut off pin; and injection molding a septum in at least a portion of the internal fluid passageway between the mold core shut off pin and the proximal end of the catheter tube through the injection mold window.

Abstract: A self activating vent cap configured to be operably coupled to a needleless connector and automatically shifted relative to the needleless connector from the first, storage position to a second, activated position upon rotation of the vent cap relative to the needleless connector. The self activating vent cap including a threaded portion, an activation portion and a biasing mechanism, wherein shifting of the activation portion to the second, activated position is selectively precluded by the interference of at least one ridge of the threaded portion with a ledge of the activation portion.

Abstract: Catheter assemblies may include introducer needles having a notch or similar structure that allows flashback blood to enter the annular space between a catheter tube and an introducer needle of an IV catheter. The presence of flashback blood in this annular space can provide a clinician with an early, visible indication that a needle has entered a vein. The notch, however, may create a leak path for blood to escape outside of the catheter assembly, unless contained. Disclosed herein is a notch containment that prevents the notch from providing a leak path for blood to escape outside of the catheter during or after needle withdrawal.

Abstract: A stopcock and sampling port device. The stopcock and sampling port device configured to reduce the occurrence of stagnation fluid flowing therethrough, the stopcock and sampling port device including a housing, an elastomeric element, a cap, a handle, and a divided septum, the housing defining an internal fluid passageway having a first port, a second port, and a third port, the divided septum operably coupled to the housing within the third port and configured to encourage turbulence of fluid passing through the third port, thereby reducing the occurrence of stagnation of fluid flowing therethrough.

Abstract: A catheter hub assembly. The catheter hub assembly includes a catheter hub body, a septum and a septum retainer, the catheter hub body having a distal end, a proximal and an internal wall defining an internal fluid passageway therebetween, the internal wall defining a transitional step within the internal fluid passageway, the septum positioned within the internal fluid passageway such that a distal end of the septum abuts up against the transitional step, the septum retainer at least partially receivable within the internal fluid passageway and having an outer wall shaped and sized to interlock with the inner wall of the catheter hub body, the outer wall including one or more lateral ribs configured to inhibit rotation of the septum retainer relative to the catheter hub body.

Abstract: An intravenous catheter assembly. The intravenous catheter assembly including a catheter and a catheter hub having a catheter hub body, a septum, and a septum retainer, the catheter hub body having an internal wall defining a transition step, wherein the septum positioned such that a first end of the septum abuts up against the transition step, the septum retainer at least partially insertable within the catheter hub body and configured to secure the septum in position.

Abstract: This invention is directed to a process for tightly binding nucleic acid to solid phase and corresponding processes for the utilization thereof. Nucleic acid is bound to solid phase matrices exhibiting sufficient hydrophilicity and electropositivity to tightly bind the nucleic acids from a sample. These processes include nucleic acid (double or single stranded DNA and RNA) capture from high volume and/or low concentration specimens, buffer changes, washes, and volume reductions, and enable the interface of solid phase bound nucleic acid with enzyme, hybridization or amplification strategies. The tightly bound nucleic acid may be used, for example, in repeated analyses to confirm results or test additional genes in both research and commercial applications. Further, a method is described for virus extraction, purification, and solid phase amplification from large volume plasma specimens.

Abstract: This invention is directed to a process for tightly binding nucleic acid to solid phase and corresponding processes for the utilization thereof. Nucleic acid is bound to solid phase matrices exhibiting sufficient hydrophilicity and electropositivity to tightly bind the nucleic acids from a sample. These processes include nucleic acid (double or single stranded DNA and RNA) capture from high volume and/or low concentration specimens, buffer changes, washes, and volume reductions, and enable the interface of solid phase bound nucleic acid with enzyme, hybridization or amplification strategies. The tightly bound nucleic acid may be used, for example, in repeated analyses to confirm results or test additional genes in both research and commercial applications. Further, a method is described for virus extraction, purification, and solid phase amplification from large volume plasma specimens.