Abstract: A trocar assembly can include a cannula, a seal cartridge, and an obturator. The seal cartridge is configured to be releasably coupled to the cannula and to be disposed at least partially within the cannula in a coupled configuration of the seal cartridge. The obturator is configured to directly latch to the cannula and to extends through the cannula and the seal cartridge in a coupled configuration of the obturator.

Abstract: Examples described herein relate to a in a group of servers: the servers attempting to perform timing synchronization based on a first group of timing signals sent via a first path. In some examples, the first comprises a first connection and based on disruption of communications by the first connection between servers in the group of servers. In some examples, the servers attempting to perform timing synchronization based on a second group of timing signals sent via a second path. In some examples, the second path does not traverse the first connection.

Abstract: An apparatus for time aware audio streams is described herein. The apparatus includes a converter and an alignment unit. The converter is to perform sample rate conversion of data from a first clock to a second clock. The alignment unit is to indicate valid sample points in the data based on a relationship between the first clock and the second clock.

Abstract: An apparatus for time aware audio streams is described herein. The apparatus includes a converter and an alignment unit. The converter is to perform sample rate conversion of data from a first clock to a second clock. The alignment unit is to indicate valid sample points in the data based on a relationship between the first clock and the second clock.

Abstract: Computer systems and methods providing personalized delivery of video files to a user's device. A computer server allows a user to create a user profile which includes information about certain user preferences, such as a favorite subject matter, favorite participant(s) and the like and, when a user connects to the computer server, the server checks a video database for video files of potential interest to the user and generates a ranking of video files of potential interest, then provides information and, if requested, the video files, to the user in order of the ranking. The ranking may be based on a variety of inputs, including both express and/or implied user preferences, the elapsed time between the publication (or creation) of a video file and the user's request therefor, the subject matter of the video file, the teams, players, and other persons included in the video file, the length of the video file, and a variety of other information about the video file.

Abstract: This invention relates to a method and an apparatus of controlling a release of a material carried by ultrasound sensitive particles, the release being caused by irradiating the ultrasound sensitive particles with an ultrasonic pulse having acoustic properties selected so as to interact with the ultrasound sensitive particles and thus causing the release of the material. The ultrasound sensitive particles comprise sub-groups of ultrasound sensitive particles, the ultrasound sensitive particles within the same sub-group having their respective acoustic property causing each respective sub-group to interact independently with the sound wave.

Abstract: The present invention relates to a hydrogel-containing temperature indicating element for use in ultrasound therapy. The temperature indicating element of the present invention and the therapeutic device and method making use of the same enable in some embodiments an automated adaptation of the power output as a function of the tissue temperature, avoiding therefore overheating or burning of the skin.

Abstract: A method for monitoring a patient (110) includes determining (114) convex hulls for pairs of monitored signals from the patient, and determining whether a perturbation has occurred (115, 116) in one or more of the convex hulls. This exemplary embodiment (110) can also include alerting an operator that a clinically significant change may have occurred (117) in the patient if each of the convex hulls has been perturbed. If only a subset of the convex hulls is perturbed, an artifact has probably occurred (118).

Abstract: An acoustic probe includes an acoustic transducer having acoustic transducer elements arranged in a one-dimensional array; and a variably-refracting acoustic lens coupled to the acoustic transducer. The variably-refracting acoustic lens has a pair of electrodes configured to adjust the focus of the variably-refracting acoustic lens in response to a selected voltage applied across the electrodes. In one embodiment, the variably-refracting acoustic lens includes a cavity, first and second fluid media disposed within the cavity, and the pair of electrodes. The speed of sound of an acoustic wave in the first fluid medium is different than the speed of sound of the acoustic wave in the second fluid medium. The first and second fluid media are immiscible with respect to each other, and the first fluid medium has a substantially different electrical conductivity than the second fluid medium.

Abstract: A phased ultrasound array for an ultrasound generating device. In one embodiment, the array includes a plurality of ultrasound elements arranged symmetrically about a point or dividing line in the array with respect to element size, shape and/or element location. In another embodiment, a majority of larger elements of the ultrasound array are arranged on a first portion of the array and a majority of smaller ultrasound elements are arranged on a second portion of the array. The first portion is closer to a preferred direction of steering than the second portion. Another method includes selecting randomly sized ultrasound elements and arranging the ultrasound elements symmetrically on the array. An additional method includes selecting randomly sized ultrasound elements and arranging the ultrasound elements wherein the larger ultrasound elements are arranged on a first portion of the array and smaller ultrasound elements are arranged on a second portion of the array.

Abstract: Described is a method for the delivery of a therapeutic agent to a mammal, particularly a human person, comprising (i) the administration of ultrasound particles that undergo a physical change when subjected to ultrasound; (ii) the administration of the therapeutic agent in an ultrasound dosage form allowing release of the therapeutic agent to be affected by the application of ultrasound, (iii) the application of ultrasound so as to affect a physical change in at least some of the ultrasound particles, and (iv) the application of ultrasound so as to stimulate release of the therapeutic agent. According to the invention the ultrasound particles are subjected to detection of their acoustic responses via echoes and/or emissions. The information thus obtained is processed and the processed information is used to adapt or adjust the ultrasound-mediated delivery of the therapeutic agent.

Abstract: The present invention relates to a hydrogel-containing temperature indicating element for use in ultrasound therapy. The temperature indicating element of the present invention and the therapeutic device and method making use of the same enable in some embodiments an automated adaptation of the power output as a function of the tissue temperature, avoiding therefore overheating or burning of the skin.

Abstract: An acoustic device is disclosed having a variably refracting acoustic fluid interface including the boundary between two separate fluid media, means for directing acoustic waves onto the interface, and an acoustic generator or transducer located in one of the fluid media with the acoustic generator having an impedance that is substantially equal to the one said fluid media to minimize signal loss and reflection.

Abstract: This invention relates to a method and an apparatus of controlling a release of a material carried by ultrasound sensitive particles, the release being caused by irradiating the ultrasound sensitive particles with an ultrasonic pulse having acoustic properties selected so as to interact with the ultrasound sensitive particles and thus causing the release of the material. The ultrasound sensitive particles comprise sub-groups of ultrasound sensitive particles, the ultrasound sensitive particles within the same sub-group having their respective acoustic property causing each respective sub-group to interact independently with the sound wave.

Abstract: The invention relates to methods and systems for monitoring and regulating radiofrequency ablation therapy in order to maximize effectiveness of treatment. The invention uses an imaging scanner to provide feedback regarding location and extent of a treated volume. The feedback is used as input data for control of intensity, duration, and/or placement of radiofrequency treatment. Control of treatment parameters is automatic and/or modulated by an operator.

Abstract: A method and apparatus for the integration of an ultrasound transducer with a SPECT imaging system is disclosed. The ultrasound transducer allows the delivery of particle-born drug therapies or thermally active therapies at the same site detected with SPECT imaging. The system includes a SPECT imaging subsystem; an ultrasound transducer for producing a signal representative of applied ultrasound and signally coupled to the SPECT imaging subsystem; and co-registering means for co-registering the signal representative of applied ultrasound in a coordinate system of SPECT imaging subsystem. The SPECT subsystem may be replaced with a SPECT/CT combined system to provide morphology that allows for treatment planning. In another embodiment, the ultrasound transducer can be used intermittently with the sequential gathering of SPECT images for tracking time-varying properties of the binding of specific SPECT contrast agents to biomarkers of disease.

Abstract: Methods and devices for enhanced ultrasound detection based upon changing temperature and ultrasound reflectivity of a temperature-dependent contrast agent bound to an ultrasound target are disclosed. The methods and devices can be used for enhanced imaging alone or in conjunction with drug delivery, with therapeutic approaches such as hyperthermia or cryotherapy or with other imaging modalities.

Abstract: Methods and devices for enhanced ultrasound detection based upon changing temperature and ultrasound reflectivity of a temperature-dependent contrast agent bound to an ultrasound target are disclosed. The methods and devices can be used for enhanced imaging alone or in conjunction with drug delivery, with therapeutic approaches such as hyperthermia or cryotherapy or with other imaging modalities.

Abstract: A method for calibrating ultrasound equipment and ultrasound contrast agents are provided that utilize polystyrene microspheres as a broad-band in vitro calibration tool. In accordance with the method a suspension of polystyrene microspheres is provided in a liquid environment in a container having an acoustic aperture. The suspension of microspheres is continuously agitated during measurement of the backscatter from the suspension of microspheres and the ultrasound equipment or contrast agent is then calibrated or adjusted to a selected backscatter setting.

Abstract: An electronic identification system comprising a transmitter for generating an electromagnetic excitation signal, one or more portable transponders for storing variable identification data, and for transmitting an information signal containing the identification data upon entering the field. Transmission of the information signal is independent of the excitation signal in both time and frequency. A radio frequency receiver is provided for receiving the information signal and in response generating output signal representing the variable identification data contained in the information signal.