Patents by Inventor Christopher Tape

Christopher Tape has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Anti-tace antibody molecules and their uses
    Patent number: 9150659
    Abstract: Anti-TACE (ADAM17) antibodies are disclosed that for the first time in the art are capable of binding to TACE, of acting as antagonists of one or more its biological activities, in particular by binding to TACE in a cross domain binding mode in which residues in both the catalytic domain and in the cysteine rich/disintegrin domains (Dis-Cys) are involved in antibody binding to TACE, helping to improve the specificity of the antibody binding and/or helping to improve inhibition of TACE biological activity. The therapeutic uses of the antibodies, in particular for the treatment of cancer are disclosed.
    Type: Grant
    Filed: January 30, 2012
    Date of Patent: October 6, 2015
    Inventors: Gillian Murphy, Christopher Tape, John McCafferty
  • ANTI-TACE ANTIBODY MOLECULES AND THEIR USES
    Publication number: 20140050738
    Abstract: Anti-TACE (ADAM17) antibodies are disclosed that for the first time in the art are capable of binding to TACE, of acting as antagonists of one or more its biological activities, in particular by binding to TACE in a cross domain binding mode in which residues in both the catalytic domain and in the cysteine rich/disintegrin domains (Dis-Cys) are involved in antibody binding to TACE, helping to improve the specificity of the antibody binding and/or helping to improve inhibition of TACE biological activity. The therapeutic uses of the antibodies, in particular for the treatment of cancer are disclosed.
    Type: Application
    Filed: January 30, 2012
    Publication date: February 20, 2014
    Applicant: Cancer Research Technology Limited
    Inventors: Gillian Murphy, Christopher Tape, John McCafferty