Abstract: Disclosed herein include antibodies or fragments thereof having specificity to a sarbecovirus spike protein. Also provided are compositions, methods, and kits for using said antibodies or fragments thereof for preventing or treating, for example a coronavirus infection.

Abstract: An electrostatic spray drying system comprising an electrostatic spray nozzle for directing electrically charged liquid into a drying chamber, a drying gas inlet from which drying gas is simultaneously directed, and a conical powder direction plenum for receiving drying gas and entrained dried powder for direction to a filter containing powder separation plenum via a connecting conduit. The powder direction plenum and connecting conduit each have a surrounding water jacket heat exchanger through which cooling water is directed for cooling the drying gas and powder below damaging temperatures prior to entry into the powder separation plenum. The powder separation plenum has a return line for redirecting separated drying gas to the drying chamber through a condenser, blower, and heater for reuse in the system, with condensed water being selectively redirected to the inlet of the powder direction plenum heat exchanger and/or to the cooling water supply.

Abstract: A fluidized bed spray drying system for drying liquid into powder including an elongated drying chamber, a spray nozzle assembly at an upper end of the drying chamber and a powder collection chamber at a lower end of the drying chamber. A drying gas inlet is provided in the powder collection chamber and a drying gas outlet is provided at an upper end of the drying chamber. A plurality of cylindrical filter elements at the upper end of the drying chamber are in communication with the exhaust gas outlet for filtering drying gas borne powder from drying gas exiting the drying chamber.

Abstract: A spray drying system for drying liquid into powder including a plurality of processing towers each including an elongated drying chamber, a spray nozzle assembly at an upper end of the drying chamber and a powder collection chamber at a lower end of the drying chamber. The powder collection chamber of each processing tower being configured to discharge power to a common conveyor system.

Abstract: An electrostatic spray dryer for drying liquid into powder including an elongated body defining a drying chamber, a spray nozzle assembly at one end of the drying chamber and a filter element housing and powder collection chamber at an opposite end. A non-structural non-metallic liner is disposed within the elongated body in spaced relation to an inner wall surface for defining an internal drying zone. The liner is releasably supported within the body for enabling selective removal and replacement following a particular usage. The illustrated elongated body has a modular construction comprising a plurality of modules, with at least one being selectively removable and replacement for altering the length of the drying chamber for a particular spray application. The liner also is replaceable with a liner of a length corresponding to the altered length of the drying chamber or with a different diameter for a particular usage.

Abstract: A spray dryer for drying liquid into powder including an elongated drying chamber, a spray nozzle assembly at an upper end of the drying chamber and a filter element housing and powder collection chamber at a lower end of the drying chamber. The filter element housing comprises a plurality of cylindrical filter elements supported from a wall of an exhaust chamber that communicates with an exhaust gas outlet of the filter element housing. In one embodiment, the filter element housing includes an inner downwardly opening cylindrical shroud surrounding the filter elements which defines an outer annular powder and drying gas passageway communicating with the powder collection chamber, and the exhaust chamber is defined by a downwardly opening conical plenum having an outer conical surface for directing drying gas and powder about the shroud into the powder collection chamber. Filter elements each have a respective reverse gas pulse cleaning device.

Abstract: A spray drying system for drying liquid into powder including a plurality of processing towers each including an elongated drying chamber, a spray nozzle assembly at an upper end of the drying chamber and a powder collection chamber at a lower end of the drying chamber. The powder collection chamber of each processing tower being configured to discharge power to a common conveyor system.

Abstract: A fluidized bed spray drying system for drying liquid into powder including an elongated drying chamber, a spray nozzle assembly at an upper end of the drying chamber and a powder collection chamber at a lower end of the drying chamber. A drying gas inlet is provided in the powder collection chamber and a drying gas outlet is provided at an upper end of the drying chamber. A plurality of cylindrical filter elements at the upper end of the drying chamber are in communication with the exhaust gas outlet for filtering drying gas borne powder from drying gas exiting the drying chamber.

Abstract: A spray dryer for drying liquid into powder including an elongated drying chamber, a spray nozzle assembly at an upper end of the drying chamber and a filter element housing and powder collection chamber at a lower end of the drying chamber. The filter element housing comprises a plurality of cylindrical filter elements supported from a wall of an exhaust chamber that communicates with an exhaust gas outlet of the filter element housing. In one embodiment, the filter element housing includes an inner downwardly opening cylindrical shroud surrounding the filter elements which defines an outer annular powder and drying gas passageway communicating with the powder collection chamber, and the exhaust chamber is defined by a downwardly opening conical plenum having an outer conical surface for directing drying gas and powder about the shroud into the powder collection chamber. Filter elements each have a respective reverse gas pulse cleaning device.

Abstract: An electrostatic spray dryer for drying liquid into powder including an elongated body defining a drying chamber, a spray nozzle assembly at one end of the drying chamber and a filter element housing and powder collection chamber at an opposite end. A non-structural non-metallic liner is disposed within the elongated body in spaced relation to an inner wall surface for defining an internal drying zone. The liner is releasably supported within the body for enabling selective removal and replacement following a particular usage. The illustrated elongated body has a modular construction comprising a plurality of modules, with at least one being selectively removable and replacement for altering the length of the drying chamber for a particular spray application. The liner also is replaceable with a liner of a length corresponding to the altered length of the drying chamber or with a different diameter for a particular usage.