Abstract: A device for processing molecular clusters of a liquid to nano-scale is provided and includes a stirring chamber having a hexagonal (or octagonal) column space; a plurality of first stirring modules, each of which has at least one first stirring blade having a left-handed swastika shape (or right-handed swastika shape) for pushing a liquid to flow; and a plurality of second stirring modules, each of which has at least one second stirring blade having a right-handed swastika shape (or left-handed swastika shape) for pushing the liquid to reversely flow. Thus, molecular clusters of the liquid are collided with each other under a condition with high temperature, high pressure and high stirring speed, until the particle diameter of the molecular clusters is reduced to a nano-scale.