Abstract: The present disclosure provides computer-aided diagnosis systems and methods. The method may include obtaining multiple medical images of one or more bones; for at least one of the multiple medical images, detecting one or more bone fracture regions of the one or more bones in the medical image; causing a management list to be displayed for managing the one or more bones; receiving an instruction related to selecting at least one of the one or more bones, the instruction being generated through the management list; and upon receiving the instruction, causing the following to be displayed: at least one of one or more reconstructed bone images related to the at least one selected bone; or a marker of the one or more detected bone fracture regions related to the at least one selected bone.

Abstract: The present disclosure relates to methods of enzymatic treatment of double-stranded PCR amplified products for eliminating or minimizing primer-dimers in multiplex PCR reactions and for the efficient ligation of adapters. The present disclosure relates to methods and compositions that allow more efficient highly multiplex target amplification compared to conventional methods, compositions and kits by minimizing laboratory steps, eliminating primer-dimers and increasing the efficiency of adapter ligation. The disclosed methods use multiple target-specific primers for specific and selective amplification of targets in a subject's genome. The disclosed methods can be used for numerous downstream procedures and analysis, including DNA sequencing.

Abstract: Embodiments of the present disclosure provide a data buffering method, electronic device and computer-readable medium. The method includes receiving, at a first node of a network, time window information from a second node of the network, the time window information defining a time window when data is transmitted from the first node to the second node. The method further includes enabling a first clock circuit of the first node at least partly based on the time window information to provide a first clock signal for data transmission from the first node to the second node. Therefore, the power consumption at the first node can be effectively reduced.

Abstract: The present disclosure relates to a method of target enrichment and amplification of selective target regions of genomes or nucleic acid samples and further analysis by systems such as NGS. The disclosure provides methods and kits that can be used in numerous downstream procedures including DNA sequencing. The disclosed methods can be utilized to sequence the target nucleic acid sequences such as to detect the presence of genetic variations for biological assays, assessment of disease, to count copies of target regions, and to allow such target enrichment prior to sequencing.

Abstract: A method for identifying the genetic sex of Portunus trituberculatus is provided. The SNP markers provided by the present invention presents biallelic heterozygosity in male individuals, but presents homozygous allele type in female individuals, and can be detected by PCR amplification and sequencing method, HRM method or KASP method. The detection method is flexible and the results are stable. Among them, the KASP and HRM detection methods have high throughput, fast detection speed, and simple application. It provides an important tool for the breeding of all-female population of P. trituberculatus.

Abstract: The present disclosure relates to compositions and methods for detection, identification and quantification of human papillomaviruses (HPV) and clinically significant sexually transmitted infections (STI) in a single amplification reaction. The disclosed method utilizes next-generation sequencing (NGS) to sequence amplified products. The present disclosure is also directed to kits containing primers specific to multiple HPV and STI targets.

Abstract: The present invention discloses a wide angle backlight lens which consists of lens mounting plate and lens body. Further, the upper outer surface of lens body is fixedly connected with the central position of the lower outer surface of lens mounting plate. Four sets of lens stands are installed near four corners of the upper outer surface of said lens mounting plate. Each set of said lens stands consists of two assembling stands. The luminous slot (4) is installed in the central position of the lower outer surface of said lens body (2) and lamp mounting slot (5) and reflective aperture (6) are installed in the central position of the upper outer surface of said lens mounting plate (1). A wide angle backlight lens described in the present invention is available for convergence and divergence of light rays according to actual needs, to improve the range of light diffusion and luminous intensity, hence realizing a higher uniformity of flares.

Abstract: The present disclosure relates to a method for the computation of the coverage of unexplained reads in the assignment of alleles for genetic analysis.

Abstract: The present disclosure relates to methods of enzymatic treatment of double-stranded PCR amplified products for eliminating or minimizing primer-dimers in multiplex PCR reactions and for the efficient ligation of adapters. The present disclosure relates to methods and compositions that allow more efficient highly multiplex target amplification compared to conventional methods, compositions and kits by minimizing laboratory steps, eliminating primer-dimers and increasing the efficiency of adapter ligation. The disclosed methods use multiple target-specific primers for specific and selective amplification of targets in a subject's genome. The disclosed methods can be used for numerous downstream procedures and analysis, including DNA sequencing.

Abstract: The present disclosure relates to compositions and methods for detection, identification and quantification of human papillomaviruses (HPV) and clinically significant sexually transmitted infections (STI) in a single amplification reaction. The disclosed method utilizes next-generation sequencing (NGS) to sequence amplified products. The present disclosure is also directed to kits containing primers specific to multiple HPV and STI targets.

Abstract: The present invention discloses a wide angle backlight lens which consists of lens mounting plate and lens body. Further, the upper outer surface of lens body is fixedly connected with the central position of the lower outer surface of lens mounting plate. Four sets of lens stands are installed near four corners of the upper outer surface of said lens mounting plate. Each set of said lens stands consists of two assembling stands. The luminous slot (4) is installed in the central position of the lower outer surface of said lens body (2) and lamp mounting slot (5) and reflective aperture (6) are installed in the central position of the upper outer surface of said lens mounting plate (1). A wide angle backlight lens described in the present invention is available for convergence and divergence of light rays according to actual needs, to improve the range of light diffusion and luminous intensity, hence realizing a higher uniformity of flares.

Abstract: The present disclosure relates to a method of target enrichment and amplification of selective target regions of genomes or nucleic acid samples and further analysis by systems such as NGS. The disclosure provides methods and kits that can be used in numerous downstream procedures including DNA sequencing. The disclosed methods can be utilized to sequence the target nucleic acid sequences such as to detect the presence of genetic variations for biological assays, assessment of disease, to count copies of target regions, and to allow such target enrichment prior to sequencing.

Abstract: Embodiments of the present disclosure provide a data buffering method, electronic device and computer-readable medium. The method includes receiving, at a first node of a network, time window information from a second node of the network, the time window information defining a time window when data is transmitted from the first node to the second node. The method further includes enabling a first clock circuit of the first node at least partly based on the time window information to provide a first clock signal for data transmission from the first node to the second node. Therefore, the power consumption at the first node can be effectively reduced.

Abstract: A method for determining the association of Human Leukocyte Antigen (HLA) alleles at adjacent loci in genomic DNA from a biological sample obtained from a human subject is disclosed. A method and system of validating correctness of an assignment of an allele variant to a genetic human leucocyte antigen (HLA) locus are also disclosed.

Abstract: This disclosure relates to arbitration of different types of requests to access a cache. Features of this disclosure can be implemented in a graphics processing unit (GPU). In one embodiment, an arbiter can receive requests from a color processor and a depth processor and determine which of the received requests has the highest priority. The request with the highest priority can then be provided to the cache. The priority can be configurable. The arbiter can determine priority, for example, based on whether a location in the cache associated with a request is available, a weight associated with the request, a number of requests of a particular type processed by the arbiter, or any combination thereof.

Abstract: Methods are provided to determine the entire genomic region of a particular HLA locus including both intron and exons. The resultant consensus sequences provides linkage information between different exons, and produces the unique sequence from each of the two genes from the individual sample being typed. The sequence information in intron regions along with the exon sequences provides an accurate HLA haplotype.

Abstract: This disclosure describes an adaptive memory address scanning technique that defines an address scanning pattern, to be used for a particular surface, based on one or more properties of the surface. In addition, a number, shape, and arrangement of sub-primitives of a surface to process in parallel may be determined. In one example of the disclosure, a memory accessing method for graphics processing comprises, determining, by a graphics processing unit (GPU), properties of a surface, determining, by the GPU, a memory address scanning technique based on the determined properties of the surface, and performing, by the GPU, at least one of a read or a write of data associated with the surface in a memory based on the determined memory address scanning technique.

Abstract: Provided herein are methods and systems useful for the determination and assignment of haplotypes for genetic loci.

Abstract: A method for determining the association of Human Leukocyte Antigen (HLA) alleles at adjacent loci in genomic DNA from a biological sample obtained from a human subject is disclosed. A method and system of validating correctness of an assignment of an allele variant to a genetic human leucocyte antigen (HLA) locus are also disclosed.

Abstract: A graphics processing unit (GPU) may include a triangle setup engine (TSE) configured to determine coordinates of a triangle, rotate coordinates of the triangle based on an angle. To rotate the coordinates, the TSE generates coordinates of the triangle in a rotated domain, and determines coordinates of a bounding box in the rotated domain based on the coordinates of the triangle in the rotated domain. The TSE determines a first plurality of parallel scanlines in the rotated domain, and a second plurality of parallel scanlines in the rotated domain. The first and second pluralities of scanlines are perpendicular. The TSE determines whether the bounding box coordinates are located within two adjacent scanlines. If the bounding box coordinates are located within the two adjacent scanlines, the TSE removes the triangle from the scene.