Patents by Inventor Chun-Yen Ke

Chun-Yen Ke has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Folate mimetics and folate-receptor binding conjugates thereof
    Patent number: 8470822
    Abstract: This present disclosure relates to folate mimetics and their use in therapeutic and diagnostic applications. More particularly, the disclosure relates to using des-glutamyl folic acid analogs recognized by and selectively bound by folate receptors and other folate binding proteins and the use of such analogs for targeted delivery of diagnostic or therapeutic agents to folate-receptor bearing cell populations.
    Type: Grant
    Filed: May 7, 2010
    Date of Patent: June 25, 2013
    Assignees: Purdue Research Foundation, Endocyte, Inc.
    Inventors: Mark A Green, Chun-Yen Ke, Christopher P Leamon
  • Folate mimetics and folate-receptor binding conjugates thereof
    Patent number: 7875612
    Abstract: A cell population expressing folate receptors is selectively targeted with a non-peptide folic acid analogue. The non-peptide folic acid analogue is conjugated to a diagnostic or therapeutic agent to enable selective delivery of the agent to the targeted cell population.
    Type: Grant
    Filed: April 24, 2002
    Date of Patent: January 25, 2011
    Assignees: Purdue Research Foundation, Endocyte, Inc.
    Inventors: Mark A. Green, Chun-Yen Ke, Christopher P. Leamon
  • Folate mimetics and folate-receptor binding conjugates thereof
    Publication number: 20050227985
    Abstract: A cell population expressing folate receptors is selectively targeted with a folate mimetic. The folate mimetic is conjugated to a diagnostic or therapeutic agent to enable selective delivery of the agent to the targeted cell population.
    Type: Application
    Filed: April 24, 2002
    Publication date: October 13, 2005
    Inventors: Mark Green, Chun-Yen Ke, Christophe Leamon
  • Folate mimetics and folate-receptor binding conjugates thereof
    Publication number: 20040242582
    Abstract: A cell population expressing folate receptors is selectively targeted with a folate mimetic. The folate mimetic is conjugated to a diagnostic or therapeutic agent to enable selective delivery of the agent to the targeted cell population.
    Type: Application
    Filed: June 21, 2004
    Publication date: December 2, 2004
    Inventors: Mark A Green, Chun-Yen Ke, Christophe P Leamon