Patents by Inventor Chunting Ye

Chunting Ye has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of determining toxicity of an immunomodulatory drug for use in humans preliminary class
    Patent number: 11959926
    Abstract: Humanized mouse models and methods are provided for determining whether administration of an immunomodulatory drug likely elicits a severe cytokine release syndrome in a human. Humanized mouse models and methods are also provided for determining the immunotoxicity in a human of a drug candidate or of drug combinations.
    Type: Grant
    Filed: June 26, 2023
    Date of Patent: April 16, 2024
    Assignee: The Jackson Laboratory
    Inventors: James Keck, Chunting Ye
  • Method of determining toxicity of an immunomodulatory drug for use in humans
    Patent number: 11959925
    Abstract: Humanized mouse models and methods are provided for determining whether administration of an immunomodulatory drug likely elicits a severe cytokine release syndrome in a human. Humanized mouse models and methods are also provided for determining the immunotoxicity in a human of a drug candidate or of drug combinations.
    Type: Grant
    Filed: April 17, 2018
    Date of Patent: April 16, 2024
    Assignee: The Jackson Laboratory
    Inventors: James Keck, Chunting Ye
  • METHOD OF DETERMINING TOXICITY OF AN IMMUNOMODULATORY DRUG FOR USE IN HUMANS
    Publication number: 20230417763
    Abstract: Humanized mouse models and methods are provided for determining whether administration of an immunomodulatory drug likely elicits a severe cytokine release syndrome in a human. Humanized mouse models and methods are also provided for determining the immunotoxicity in a human of a drug candidate or of drug combinations.
    Type: Application
    Filed: June 26, 2023
    Publication date: December 28, 2023
    Applicant: The Jackson Laboratory
    Inventors: James Keck, Chunting Ye
  • HUMANIZED MOUSE MODELS FOR ASSESSING IMMUNE CELL THERAPY
    Publication number: 20220214330
    Abstract: Provided herein are humanized mouse models and methods for determining whether administration of engineered immune cell therapies likely elicit cytokine release syndrome and/or determining the efficacy of an anti-disease therapy. Further, the models provided herein may be used to test the efficacy of different anti-CRS therapies.
    Type: Application
    Filed: March 25, 2022
    Publication date: July 7, 2022
    Applicant: The Jackson Laboratory
    Inventors: James Keck, Jing Jiao, Chunting Ye
  • METHOD OF DETERMINING TOXICITY OF AN IMMUNOMODULATORY DRUG FOR USE IN HUMANS
    Publication number: 20220003781
    Abstract: Humanized mouse models and methods are provided for determining whether administration of an immunomodulatory drug likely elicits a severe cytokine release syndrome in a human. Humanized mouse models and methods are also provided for determining the immunotoxicity in a human of a drug candidate or of drug combinations.
    Type: Application
    Filed: April 17, 2018
    Publication date: January 6, 2022
    Applicant: The Jackson Laboratory
    Inventors: James Keck, Chunting Ye
  • METHOD OF DETERMINING TOXICITY OF AN IMMUNOMODULATORY DRUG FOR USE IN HUMANS
    Publication number: 20210132080
    Abstract: Humanized mouse models and methods are provided for determining whether administration of an immunomodulatory drug likely elicits a severe cytokine release syndrome in a human. Humanized mouse models and methods are also provided for determining the immunotoxicity in a human of a drug candidate or of drug combinations.
    Type: Application
    Filed: April 17, 2018
    Publication date: May 6, 2021
    Applicant: The Jackson Laboratory
    Inventors: James Keck, Chunting Ye