Patents by Inventor Cindra A. Widrig Opalsky
Cindra A. Widrig Opalsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7977106Abstract: This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate.Type: GrantFiled: May 21, 2010Date of Patent: July 12, 2011Assignee: Abbott Point of Care Inc.Inventors: Cindra A. Widrig Opalsky, David Opalsky, Andrzej Maczuszenko, Imants R. Lauks, Rhonda J. Cheadle
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Patent number: 7923256Abstract: This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate.Type: GrantFiled: May 21, 2010Date of Patent: April 12, 2011Assignee: Abbott Point of Care Inc.Inventors: Cindra A. Widrig Opalsky, David Opalsky, Andrzej MacZuszenko, Imants R. Lauks, Rhonda J. Cheadle
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Publication number: 20100240067Abstract: This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate.Type: ApplicationFiled: May 21, 2010Publication date: September 23, 2010Applicant: ABBOTT POINT OF CARE INC.Inventors: Cindra A. Widrig Opalsky, David Opalsky, Andrzej MacZuszenko, Imants R. Lauks, Rhonda J. Cheadle
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Publication number: 20100240136Abstract: This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate.Type: ApplicationFiled: May 21, 2010Publication date: September 23, 2010Applicant: ABBOTT POINT OF CARE INC.Inventors: Cindra A. Widrig Opalsky, David Opalsky, Andrzej MacZuszenko, Imants R. Lauks, Rhonda J. Cheadle
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Patent number: 7736901Abstract: This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate.Type: GrantFiled: March 24, 2004Date of Patent: June 15, 2010Assignee: Abbot Point Of Care Inc.Inventors: Cindra A. Widrig Opalsky, David Opalsky, Andrezej Maczuszenko, Imants R. Lauks, Rhonda J. Cheadle
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Publication number: 20040175296Abstract: This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate.Type: ApplicationFiled: March 24, 2004Publication date: September 9, 2004Inventors: Cindra A. Widrig Opalsky, David Opalsky, Andrzej MacZuszenko, Imants R. Lauks, Rhonda J. Cheadle
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Patent number: 6750053Abstract: This invention is a disposable cartridge for use at the patient side to perform traditional coagulation assays on fresh whole blood or blood derivative samples. The cartridge, in use with an electronic analyzer allows a fluid sample to be metered and quantitatively mixed with reagents which activate the coagulation cascade. An artificial substrate for thrombin, the enzyme whose action results in clot formation is also provided. Clot formation is subsequently detected using a microfabricated sensor also housed within the cartridge which detects electrochemically the product of the thrombin reaction upon the synthetic substrate.Type: GrantFiled: November 15, 2000Date of Patent: June 15, 2004Assignee: i-STAT CorporationInventors: Cindra A. Widrig Opalsky, David Opalsky, Andy Maczuszenko, Imants R. Lauks, Rhonda J. Cheadle
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Publication number: 20020177958Abstract: A sample analyzing system includes at least one sensor located at least partially within a sample retaining area. In addition, the sensor has at least one edge defining a sample detection location. This sample detection location defines an area within which the sensor is capable of detecting a presence or an absence of the sample. The system analyzes sample data by first introducing the sample into the sample retaining area and then mixing a reagent with the sample to commence formation of a reagent product. After mixing and upon detecting the absence of the sample from the sample detection location by the at least one sensor, an edge of the sample is moved past an edge of the at least one sensor and into the sample detection location. Then, upon detecting the presence of the sample in the sample detection location by the at least one sensor, the edge of the sample is moved past the edge of the at least one sensor and out of the sample detection location.Type: ApplicationFiled: July 8, 2002Publication date: November 28, 2002Applicant: i-STAT CorporationInventors: Cindra A. Widrig Opalsky, David Opalsky, Andy Maczuszenko, Imants R. Lauks
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Patent number: 6438498Abstract: A sample analyzing system includes at least one sensor located at least partially within a sample retaining area. In addition, the sensor has at least one edge defining a sample detection location. This sample detection location defines an area within which the sensor is capable of detecting a presence or an absence of the sample. The system analyzes sample data by first introducing the sample into the sample retaining area and then mixing a reagent with the sample to commence formation of a reagent product. After mixing and upon detecting the absence of the sample from the sample detection location by the at least one sensor, an edge of the sample is moved past an edge of the at least one sensor and into the sample detection location. Then, upon detecting the presence of the sample in the sample detection location by the at least one sensor, the edge of the sample is moved past the edge of the at least one sensor and out of the sample detection location.Type: GrantFiled: March 17, 2000Date of Patent: August 20, 2002Assignee: I-Stat CorporationInventors: Cindra A. Widrig Opalsky, David Opalsky, Andy Maczuszenko, Imants R. Lauks