Abstract: A restraining device is provided for restraining an infant in an isolette or incubator, allowing the infant to be transported in such device. A tray is adapted for secured receipt within the isolette. A foam pad is received by the tray, the pad having a recess contoured therein to accommodate and receive an infant. The recess is preferably topographically sculptured to more securely receive the infant and to prevent movement of the infant within the recess. A belt or harness passes from the tray and through the sculptured recess to engage and secure the infant therein. Accordingly, with the isolette secured to the vehicle, the tray secured to the isolette, and the infant secured through the harness to the tray, the infant cannot move about within the isolette when being transported or when the transporting vehicle experiences abrupt changes in motion.