Patents by Inventor Cindy SCHULENBURG

Cindy SCHULENBURG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTI-A2AP ANTIBODIES AND USES THEREOF
    Publication number: 20240034810
    Abstract: The present invention relates to an isolated antibody or antigen-binding fragment thereof that binds to human A2AP. The isolated antibody or antigen-binding fragment according to the present invention i) cross-reacts with rabbit and/or cynomolgus A2AP, ii) does not inhibit human plasmin activity, and iii) increases plasmin mediated clot lysis in the presence of A2AP.
    Type: Application
    Filed: June 6, 2023
    Publication date: February 1, 2024
    Inventors: Stefan HEITMEIER, Julia Glunz, Melanie Fischer, Cindy Schulenburg, Hannah Jörissen, Christoph Thiel, Andreas Wilmen, Ernst Weber
  • NOVEL ANTI-A2AP ANTIBODIES AND USES THEREOF
    Publication number: 20240010750
    Abstract: The present invention relates to an isolated antibody or antigen-binding fragment thereof that binds to human A2AP. The isolated antibody or antigen-binding fragment according to the present invention i) cross-reacts with rabbit and/or cynomolgus A2AP, ii) does not inhibit human plasmin activity, and iii) increases plasmin mediated clot lysis in the presence of A2AP.
    Type: Application
    Filed: September 13, 2021
    Publication date: January 11, 2024
    Inventors: Stefan HEITMEIER, Julia GLUNZ, Melanie FISCHER, Cindy SCHULENBURG, Hannah JÖRISSEN, Christoph THIEL, Andreas WILMEN, Ernst WEBER
  • IMMUNOCONJUGATES
    Publication number: 20230192795
    Abstract: The present invention generally relates to mutant interleukin-7 polypeptides, immunoconjugates, particularly immunoconjugates comprising a mutant interleukin-7 polypeptide and an antibody that binds to PD-1. In addition, the invention relates to polynucleotide molecules encoding the mutant interleukin-7 polypeptides or the immunoconjugates, and vectors and host cells comprising such polynucleotide molecules. The invention further relates to methods for producing the mutant interleukin-7 polypeptides, immunoconjugates, pharmaceutical compositions comprising the same, and uses thereof.
    Type: Application
    Filed: April 13, 2021
    Publication date: June 22, 2023
    Applicant: Hoffmann-La Roche Inc.
    Inventors: Laura Codarri Deak, Anne Freimoser-Grundschober, Christian Klein, Laura Lauener, Ekkehard Moessner, Cindy Schulenburg, Pablo Umaña, Eleni Maria Varypataki
  • RNA-programmable endonuclease systems and their use in genome editing and other applications
    Patent number: 11578323
    Abstract: Aspects of this invention inter alia relate to novel systems for targeting, editing or manipulating DNA in a cell, comprising one or more heterologous vector(s) encoding a SluCas9 nuclease from Staphylococcus lugdunensis or variants thereof, and one or more guide RNAs (gRNAs), or a SluCas9 nuclease or variant thereof and one or more gRNAs.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: February 14, 2023
    Assignees: BAYER HEALTHCARE LLC, CRISPR THERAPEUTICS AG
    Inventors: Andre Cohnen, Moritz Schmidt, Wayne Coco, Ashish Gupta, Jan Tebbe, Cindy Schulenburg, Christian Pitzler, Michael Biag Gamalinda, Sabine Jach, Florian Richter, Anup Arumughan, Corinna Saalwächter
  • NUCLEIC ACIDS ENCODING IMPROVED TRANSAMINASE PROTEINS
    Publication number: 20220220457
    Abstract: The present invention concerns proteins having improved omega-transaminase (?-TA) activity, nucleic acid molecules encoding respective proteins having improved ?-TA activity and methods for stereo selective synthesis of chiral amines and amino acids or increasing of chiral amines isomers in enantiomer mixtures.
    Type: Application
    Filed: July 30, 2019
    Publication date: July 14, 2022
    Inventors: Nina BOHLKE, Wayne COCO, Mark James FORD, Saskia FUNK, Ulrike KELLER, Oliver KENSCH, Ksenia NIESEL, Nilkolaus PAWLOWSKI, Moritz SCHON, Cindy SCHULENBURG, Andreas Karl STEIB, Christina THIES
  • NOVEL RNA-PROGRAMMABLE ENDONUCLEASE SYSTEMS AND THEIR USE IN GENOME EDITING AND OTHER APPLICATIONS
    Publication number: 20200385720
    Abstract: Aspects of this invention inter alia relate to novel systems for targeting, editing or manipulating DNA in a cell, comprising one or more heterologous vector(s) encoding a SluCas9 nuclease from Staphylococcus lugdunensis or variants thereof, and one or more guide RNAs (gRNAs), or a SluCas9 nuclease or variant thereof and one or more gRNAs.
    Type: Application
    Filed: December 14, 2018
    Publication date: December 10, 2020
    Inventors: Andre COHNEN, Moritz SCHMIDT, Wayne COCO, Ashish GUPTA, Jan TEBBE, Cindy SCHULENBURG, Christian PITZLER, Michael Biag GAMALINDA, Sabine JACH, Florian RICHTER, Anup ARUMUGHAN, Corinna SAALWÄCHTER