Patents by Inventor Clara Montagut Viladot

Clara Montagut Viladot has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF TREATING CANCER BASED ON IDENTIFYING MUTATIONS IN THE EXTRACELLULAR DOMAIN III OF EPIDERMAL GROWTH FACTOR RECEPTOR GENE
    Publication number: 20210262037
    Abstract: The invention relates to new identified mutations in the epidermal growth factor receptor gene, leading to amino acidic changes which highly correlate with the resistance to a therapy regimen comprising cetuximab. The invention includes peptide sequences and primers to detect the mutations, as well as kits for predicting the response of a subject to a therapy regime comprising cetuximab. In particular, the invention is useful in the therapy regimen applicable to metastasic colorectal cancer.
    Type: Application
    Filed: January 21, 2021
    Publication date: August 26, 2021
    Inventors: Alberto BARDELLI, Sabrina ARENA, Clara MONTAGUT VILADOT, Joan ALBANELL MESTRES, Ana ROVIRA GUERIN, Beatriz BELLOSILLO PARICIO, Alba DALMASES MASSEGÚ
  • Method of treating cancer based on identifying mutations in the extracellular domain III of epidermal growth factor receptor gene
    Patent number: 11015225
    Abstract: The invention relates to new identified mutations in the epidermal growth factor receptor gene, leading to amino acidic changes which highly correlate with the resistance to a therapy regimen comprising cetuximab. The invention includes peptide sequences and primers to detect the mutations, as well as kits for predicting the response of a subject to a therapy regime comprising cetuximab. In particular, the invention is useful in the therapy regimen applicable to metastasic colorectal cancer.
    Type: Grant
    Filed: December 30, 2014
    Date of Patent: May 25, 2021
    Assignees: FUNDACIÓ INSTITUT MAR D'INVESTIGACIONS MEDIQUES (IMIM)
    Inventors: Alberto Bardelli, Sabrina Arena, Clara Montagut Viladot, Joan Albanell Mestres, Ana Rovira Guerin, Beatriz Bellosillo Paricio, Alba Dalmases Massegú
  • Mutations in the epidermal growth factor receptor gene
    Patent number: 9765399
    Abstract: The invention relates to a new identified mutation in the epidermal growth factor receptor gene, leading to an amino acidic change which highly correlates with the resistance to a therapy regimen comprising cetuximab and the sensitivity to a therapy regimen comprising panitumumab. The invention includes peptide sequences, primers and probes to detect such a mutation, as well as kits for predicting the response of a subject to a therapy regime comprising cetuximab and/or panitumumab. In particular, the invention is useful in the therapy regimen applicable to metastasic colorectal cancer and to head and neck cancer.
    Type: Grant
    Filed: August 2, 2012
    Date of Patent: September 19, 2017
    Assignee: FUNDACIO INSTITUT MAR D'INVESTIGACIONS MEDIQUES (IMIM)
    Inventors: Clara Montagut Viladot, Joan Albanell Mestres, Ana Rovira Guerin, Beatriz Bellosillo Paricio, Alba Dalmases Massegú
  • MUTATIONS IN THE EXTRACELLULAR DOMAIN III OF EPIDERMAL GROWTH FACTOR RECEPTOR GENE
    Publication number: 20170260250
    Abstract: The invention relates to new identified mutations in the epidermal growth factor receptor gene, leading to amino acidic changes which highly correlate with the resistance to a therapy regimen comprising cetuximab. The invention includes peptide sequences and primers to detect the mutations, as well as kits for predicting the response of a subject to a therapy regime comprising cetuximab. In particular, the invention is useful in the therapy regimen applicable to metastasic colorectal cancer.
    Type: Application
    Filed: December 30, 2014
    Publication date: September 14, 2017
    Inventors: Alberto BARDELLI, Sabrina ARENA, Clara MONTAGUT VILADOT, Joan ALBANELL MESTRES, Ana ROVIRA GUERIN, Beatriz BELLOSILLO PARICIO, Alba DALMASES MASSEGÚ
  • MUTATIONS IN THE EPIDERMAL GROWTH FACTOR RECEPTOR GENE
    Publication number: 20140170662
    Abstract: The invention relates to a new identified mutation in the epidermal growth factor receptor gene, leading to an amino acidic change which highly correlates with the resistance to a therapy regimen comprising cetuximab and the sensitivity to a therapy regimen comprising panitumumab. The invention includes peptide sequences, primers and probes to detect such a mutation, as well as kits for predicting the response of a subject to a therapy regime comprising cetuximab and/or panitumumab. In particular, the invention is useful in the therapy regimen applicable to metastasic colorectal cancer and to head and neck cancer.
    Type: Application
    Filed: August 2, 2012
    Publication date: June 19, 2014
    Inventors: Clara Montagut Viladot, Joan Albanell Mestres, Ana Rovira Guerin, Beatriz Bellosillo Paricio, Alba Dalmases Massegú