Patents by Inventor Claude Vernhet

Claude Vernhet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted 1-alkylcinnolin-4(1)-one derivatives, preparation thereof and therapeutic application of same
    Patent number: 8420651
    Abstract: The subject of the present invention is compounds corresponding to the formula (I) in which: X represents a divalent (C2-C5)alkylene radical which is unsubstituted or substituted one or more times by an Alk group; R1 represents a phenyl, a naphthyl, a pyridyl, a 1-benzothienyl or a 1,3-benzodioxolyl; R2 represents a hydrogen atom, a halogen atom, an Alk group, an OAlk group or else a group chosen from —S-Alk, —SO-Alk, —SO2-Alk, —CO—N(R4)-Alk, —N(R4)SO2-Alk, —N(R4)CO-Alk, —N(R4)SO2—N(Alk)2; R3 represents a hydrogen atom, a halogen atom, an Alk group or an OAlk group; R4 represents a hydrogen atom or a (C1-C4)alkyl; Alk represents an unsubstituted or substituted (C1-C4)alkyl. Preparation process and therapeutic application.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: April 16, 2013
    Assignee: Sanofi
    Inventors: Elodie Barbagallo, Carole Legeay, Murielle Rinaldi-Carmona, Pascale Roux, Claude Vernhet
  • Substituted 1-benzyl-cinnolin-4(1)-one derivatives, preparation thereof, and therapeutic use thereof
    Patent number: 8410099
    Abstract: The present invention is related to novel substituted 1-benzylcinnolin-4(1H)-one derivatives having affinity for cannabinoid CB2 receptors, their preparation and their therapeutic application.
    Type: Grant
    Filed: January 10, 2011
    Date of Patent: April 2, 2013
    Assignee: Sanofi
    Inventors: Claude Vernhet, Elodie Barbagallo, Murielle Rinaldi-Carmona, Pascale Roux
  • SUBSTITUTED 1-ALKYLCINNOLIN-4(1H)-ONE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC APPLICATION OF SAME
    Publication number: 20120129864
    Abstract: The subject of the present invention is compounds corresponding to the formula (I) in which: X represents a divalent (C2-C5)alkylene radical which is unsubstituted or substituted one or more times by an Alk group; R1 represents a phenyl, a naphthyl, a pyridyl, a 1-benzothienyl or a 1,3-benzodioxolyl; R2 represents a hydrogen atom, a halogen atom, an Alk group, an OAlk group or else a group chosen from —S-Alk, —SO-Alk, —SO2-Alk, —CO—N(R4)-Alk, —N(R4)SO2-Alk, —N(R4)CO-Alk, —N(R4)SO2—N(Alk)2; R3 represents a hydrogen atom, a halogen atom, an Alk group or an OAlk group; R4 represents a hydrogen atom or a (C1-C4)alkyl; Alk represents an unsubstituted or substituted (C1-C4)alkyl. Preparation process and therapeutic application.
    Type: Application
    Filed: April 6, 2010
    Publication date: May 24, 2012
    Applicant: SANOFI
    Inventors: Elodie Barbagallo, Carole Legeay, Murielle Rinaldi-Carmona, Pascale Roux, Claude Vernhet
  • SUBSTITUTED 1-BENZYL-CINNOLIN-4(1H)-ONE DERIVATIVES, PREPARATION THEREOF, AND THERAPEUTIC USE THEREOF
    Publication number: 20110144115
    Abstract: The present invention is related to novel substituted 1-benzylcinnolin-4(1H)-one derivatives having affinity for cannabinoid CB2 receptors, their preparation and their therapeutic application.
    Type: Application
    Filed: January 10, 2011
    Publication date: June 16, 2011
    Applicant: SANOFI-AVENTIS
    Inventors: Claude Vernhet, Elodie Barbagallo, Murielle Rinaldi-Carmona, Pascale Roux
  • 3-Acylindole derivatives, preparation and therapeutic use thereof
    Patent number: 7741363
    Abstract: The invention relates to compounds of formula (I), wherein X, R1, R2, R3, R4 and R5 are as described herein. The invention also includes preparative methods for the preparation of compounds of formula (I). A method for the therapeutic use of the inventive compounds is also disclosed and claimed.
    Type: Grant
    Filed: May 14, 2008
    Date of Patent: June 22, 2010
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Claude Vernhet, Murielle Rinaldi-Carmona, CaroleElisabeth Guillaumont-Legeay
  • 3-ACYLINDOLE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF
    Publication number: 20080275102
    Abstract: The invention relates to compounds of formula (I), wherein X, R1, R2, R3, R4 and R5 are as described herein. The invention also includes preparative methods for the preparation of compounds of formula (I). A method for the therapeutic use of the inventive compounds is also disclosed and claimed.
    Type: Application
    Filed: May 14, 2008
    Publication date: November 6, 2008
    Applicant: SANOFI-AVENTIS
    Inventors: Francis BARTH, Claude VERNHET, Murielle RINALDI-CARMONA, Carole Elisabeth GUILLAUMONT-LEGEAY
  • Derivatives of indole-3-carboxamide, preparation method thereof and application of same in therapeutics
    Patent number: 7202268
    Abstract: The invention relates to derivatives of indole-3-carboxamide having general formula (I): wherein: R1 represents a C3–C10 alkyl, a C5–C10 carbocyclic radical that is unsubstituted or substituted one or more times with a methyl group; R2 represents a hydrogen atom or a (C1–C4)alkyl group; R3 represents a halogen atom or a (C1–C4)alkyl group; R4 represents a hydrogen or halogen atom or a (C1–C4)alkyl group; R5 represents a (C1–C4)alkyl group or a trifluoromethyl; X represents a sulfur atom, an —NHSO2— group or an —SO2— group; and n is equal to 2 or 3. The invention also relates to a method of preparing the aforementioned derivatives and to the application of same in therapeutics.
    Type: Grant
    Filed: May 26, 2005
    Date of Patent: April 10, 2007
    Assignee: Sanofi-aventis
    Inventors: Francis Barth, Mireille Rinaldi-Carmona, Claude Vernhet
  • Indole derivatives, method for preparing same and pharmaceutical compositions containing same
    Patent number: 7138424
    Abstract: The present invention provides compounds of formula: and also provides their preparation and the pharmaceutical compositions comprising them. These compounds are ligands of CB2 cannabinoid receptors.
    Type: Grant
    Filed: May 15, 2003
    Date of Patent: November 21, 2006
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Carole Guillaumont, Murielle Rinaldi-Carmona, Claude Vernhet
  • Indole derivatives, method for preparating same and pharmaceutical compositions containing same
    Publication number: 20060089345
    Abstract: The present invention provides compounds of formula: and also provides their preparation and the pharmaceutical compositions comprising them. These compounds are ligands of CB2 cannabinoid receptors.
    Type: Application
    Filed: May 15, 2003
    Publication date: April 27, 2006
    Inventors: Francis Barth, Carole Guillaumont, Murielle Rinaldi-Carmona, Claude Vernhet
  • 3-arylindole derivatives and their use as CBreceptor agonists
    Patent number: 6995184
    Abstract: A subject-matter of the present invention is compounds of formula: and their preparation and the pharmaceutical compositions comprising them. These compounds are agonists for CB2 cannabinoid receptors.
    Type: Grant
    Filed: November 21, 2001
    Date of Patent: February 7, 2006
    Assignee: Sanofi-Aventis
    Inventors: Francis Barth, Christian Congy, Carole Guillaumont, Murielle Rinaldi, Fabienne Vasse, Claude Vernhet
  • Derivatives of indole-3-carboxamide, preparation method thereof and application of same in therapeutics
    Publication number: 20050288356
    Abstract: The invention relates to derivatives of indole-3-carboxamide having general formula (I): wherein: R1 represents a C3-C10 alkyl, a C5-C10 carbocyclic radical that is unsubstituted or substituted one or more times with a methyl group; R2 represents a hydrogen atom or a (C1-C4)alkyl group; R3 represents a halogen atom or a (C1-C4)alkyl group; R4 represents a hydrogen or halogen atom or a (C1-C4)alkyl group; R5 represents a (C1-C4)alkyl group or a trifluoromethyl; X represents a sulfur atom, an —NHSO2— group or an —SO2— group; and n is equal to 2 or 3. The invention also relates to a method of preparing the aforementioned derivatives and to the application of same in therapeutics.
    Type: Application
    Filed: May 26, 2005
    Publication date: December 29, 2005
    Applicant: Sanofi-Aventis
    Inventors: Francis Barth, Mireille Rinaldi-Carmona, Claude Vernhet
  • 3-Arylindole derivatives and their use as cb2 receptor agonists
    Publication number: 20040034090
    Abstract: A subject-matter of the present invention is compounds of formula: 1
    Type: Application
    Filed: May 13, 2003
    Publication date: February 19, 2004
    Inventors: Francis Barth, Christian Congy, Carole Guillaumont, Murielle Rinaldi, Fabienne Vasse, Claude Vernhet