Abstract: The present invention relates to a simple, robust and effective process for preparing a dry powder inhalation formulation containing at least one drug, preferably a highly active drug, more preferably Tiotropium bromide or Tiotropium bromide monohydrate, and a lactose carrier. The process is characterized in that a three-layered composition containing a drug layer in between layers of the lactose carrier is mixed and the obtained preblend is mixed with additional lactose carrier. The process combines a simple manufacturing procedure with an excellent content uniformity obtained over a wide range of mixing parameters.

Abstract: A transdermal patch includes a protective layer, a matrix layer, an adhesive layer, and a cover layer. The cover layer is at least partially bi-elastic, and the adhesive layer comprises an acrylic copolymer having hydroxyl functional groups. The matrix layer comprises a physiologically effective amount of buprenorphine or pharmaceutically acceptable salts thereof.

Abstract: A transdermal patch includes a protective layer, a matrix layer, an adhesive layer, and a cover layer. The cover layer is at least partially bi-elastic, and the adhesive layer comprises an acrylic copolymer having hydroxyl functional groups. The matrix layer comprises a physiologically effective amount of buprenorphine or pharmaceutically acceptable salts thereof.

Abstract: Method of reducing the pour-point and improving the flowability of petroleum oil or a fraction thereof by adding thereto a flowability-improving quantity of at least one copolymer of (a) an acrylic acid ester, a methacrylic acid ester, or a mixture of an acrylic acid ester and a methacrylic acid ester, and (b) not more than 20% by weight, based on the weight of the copolymer, of acrylic acid, methacrylic acid, or a mixture of acrylic acid and methacrylic acid, and wherein said esters in component (a) are esters of a C.sub.16 or higher alcohol or an alcohol mixture wherein at least 75% by weight thereof is one or more alcohols containing at least 16 carbon atoms; and the compositions resulting therefrom.