Patents by Inventor Claudia Palena

Claudia Palena has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Yeast-brachyury immunotherapeutic compositions
    Patent number: 11944673
    Abstract: Disclosed are yeast-based immunotherapeutic compositions comprising Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: April 2, 2024
    Assignees: The USA, as represented by the Secretary, Dept. of Health and Human Services, GlobeImmune, Inc.
    Inventors: Claudia Palena, Zhimin Guo, David Apelian, Jeffrey Schlom
  • Yeast-brachyury immunotherapeutic compositions
    Patent number: 11938175
    Abstract: Disclosed are yeast-based immunotherapeutic compositions comprising Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: March 26, 2024
    Assignees: The USA, as represented by the Secretary, Dept. of Health and Human Services, GlobeImmune, Inc.
    Inventors: Claudia Palena, Zhimin Guo, David Apelian, Jeffrey Schlom
  • Modified yeast-brachyury immunotherapeutic compositions
    Patent number: 11065313
    Abstract: Disclosed are improved yeast-based immunotherapeutic compositions comprising modified Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury.
    Type: Grant
    Filed: August 1, 2016
    Date of Patent: July 20, 2021
    Assignees: GlobeImmune, Inc., The USA, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Thomas H. King, Zhimin Guo, Jeffrey Schlom, Claudia Palena
  • YEAST-BRACHYURY IMMUNOTHERAPEUTIC COMPOSITIONS
    Publication number: 20210106666
    Abstract: Disclosed are yeast-based immunotherapeutic compositions comprising Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury.
    Type: Application
    Filed: December 21, 2020
    Publication date: April 15, 2021
    Inventors: Claudia Palena, Zhimin Guo, David Apelian, Jeffrey Schlom
  • YEAST-BASED IMMUNOTHERAPY FOR CHORDOMA
    Publication number: 20200046818
    Abstract: Disclosed are methods of the treatment or prevention of chordoma which include the step of administering a yeast-based immunotherapeutic composition. The yeast-based immunotherapeutic composition preferably comprises a Brachyury antigen.
    Type: Application
    Filed: October 25, 2019
    Publication date: February 13, 2020
    Inventors: Timothy C. RODELL, David APELIAN, Claudia PALENA, Jeffrey SCHLOM
  • Yeast-based immunotherapy for Chordoma
    Patent number: 10507235
    Abstract: One embodiment of the invention relates to a method to treat chordoma in an individual who has chordoma. The method includes the step of administering to an individual who has chordoma, an immunotherapeutic composition comprising: (a) a yeast vehicle; and (b) a cancer antigen comprising at least one Brachyury antigen. Another embodiment of the invention relates to the use of an immunotherapeutic composition comprising a yeast vehicle and a cancer antigen comprising at least one Brachyury antigen to chordoma in an individual who has chordoma. Yet another embodiment of the invention relates to the use an immunotherapeutic composition comprising a yeast vehicle.
    Type: Grant
    Filed: March 19, 2014
    Date of Patent: December 17, 2019
    Assignees: GlobeImmune, Inc., The USA, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Timothy C. Rodell, David Apelian, Claudia Palena, Jeffrey Schlom
  • YEAST-BRACHYURY IMMUNOTHERAPEUTIC COMPOSITIONS
    Publication number: 20190374624
    Abstract: Disclosed are yeast-based immunotherapeutic compositions comprising Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury.
    Type: Application
    Filed: April 19, 2019
    Publication date: December 12, 2019
    Inventors: Claudia Palena, Zhimin Guo, David Apelian, Jeffrey Schlom
  • Yeast-brachyury immunotherapeutic compositions
    Patent number: 10363294
    Abstract: Disclosed are yeast-based immunotherapeutic compositions comprising Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: July 30, 2019
    Assignees: GlobeImmune, Inc., The United States of America, as represented by the Secretary, Department of Health and Human Services
    Inventors: Claudia Palena, Zhimin Guo, David Apelian, Jeffrey Schlom
  • MODIFIED YEAST-BRACHYURY IMMUNOTHERAPEUTIC COMPOSITIONS
    Publication number: 20180214525
    Abstract: Disclosed are improved yeast-based immunotherapeutic compositions comprising modified Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury.
    Type: Application
    Filed: August 1, 2016
    Publication date: August 2, 2018
    Inventors: Thomas H. KING, Zhimin GUO, Jeffrey SCHLOM, Claudia PALENA
  • YEAST-BRACHYURY IMMUNOTHERAPEUTIC COMPOSITIONS
    Publication number: 20170246276
    Abstract: Disclosed are yeast-based immunotherapeutic compositions comprising Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury.
    Type: Application
    Filed: March 9, 2017
    Publication date: August 31, 2017
    Inventors: Claudia Palena, Zhimin Guo, David Apelian, Jeffrey Schlom
  • Yeast-brachyury immunotherapeutic compositions
    Patent number: 9623097
    Abstract: Disclosed are yeast-based immunotherapeutic compositions comprising Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury.
    Type: Grant
    Filed: October 29, 2015
    Date of Patent: April 18, 2017
    Assignees: GlobeImmune, Inc., The United States of America, as represented by the Secretary, Dept. of Health and Human Services
    Inventors: Claudia Palena, Zhimin Guo, David Apelian, Jeffrey Schlom
  • YEAST-BASED IMMUNOTHERAPY FOR CHORDOMA
    Publication number: 20160271238
    Abstract: One embodiment of the invention relates to a method to treat chordoma in an individual who has chordoma. The method includes the step of administering to an individual who has chordoma, an immunotherapeutic composition comprising: (a) a yeast vehicle; and (b) a cancer antigen comprising at least one Brachyury antigen. Another embodiment of the invention relates to the use of an immunotherapeutic composition comprising a yeast vehicle and a cancer antigen comprising at least one Brachyury antigen to chordoma in an individual who has chordoma. Yet another embodiment of the invention relates to the use an immunotherapeutic composition comprising a yeast vehicle.
    Type: Application
    Filed: March 19, 2014
    Publication date: September 22, 2016
    Inventors: Timothy C. RODELL, David APELIAN, Claudia PALENA, Jeffrey SCHLOM
  • YEAST-BRACHYURY IMMUNOTHERAPEUTIC COMPOSITIONS
    Publication number: 20160106824
    Abstract: Disclosed are yeast-based immunotherapeutic compositions comprising Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury.
    Type: Application
    Filed: October 29, 2015
    Publication date: April 21, 2016
    Inventors: Claudia Palena, Zhimin Guo, David Apelian, Jeffrey Schlom
  • Yeast-Brachyury immunotherapeutic compositions
    Patent number: 9198941
    Abstract: Disclosed are yeast-based immunotherapeutic compositions comprising Brachyury antigens, and methods for the prevention and/or treatment of cancers characterized by the expression or overexpression of Brachyury.
    Type: Grant
    Filed: March 14, 2013
    Date of Patent: December 1, 2015
    Assignees: The United States of America, as represented by the Secretary, Dept. of Health and Human Services, GlobeImmune, Inc.
    Inventors: Claudia Palena, Zhimin Guo, David Apelian, Jeffrey Schlom