Abstract: The present invention relates to a compound of general formula (I) inhibiting the transforming growth factor-? (TGF-?) type I receptor (ALK5), methods of preparing such compounds, pharmaceutical compositions containing them and therapeutic use thereof. The compounds of the invention may be useful in the treatment of diseases or conditions associated with a dysregulation of ALK5 signaling pathway in a mammal.

Abstract: The present disclosure provides methods related to infiltration of aircraft brake discs with titanium-containing compounds. In various embodiments, a method of making a self-coating carbon/carbon composite member may comprise infiltrating a carbonized fiber preform with a titanium-containing compound, drying the carbonized fiber preform, annealing the carbonized fiber preform at a third temperature, and densifying the carbonized fiber preform.

Abstract: The present disclosure provides methods related to infiltration of aircraft brake discs with titanium-containing compounds. In various embodiments, a method of making a self-coating carbon/carbon composite member may comprise infiltrating a carbonized fiber preform with a titanium-containing compound, drying the carbonized fiber preform, annealing the carbonized fiber preform at a third temperature, and densifying the carbonized fiber preform.

Abstract: Equipment for the comprehensive care of critical neonates that ventilates, incubates, monitors and facilitates medical procedures. This equipment includes a thermal ring keeping the neonatal bubble tempered, and that slides longitudinally through its axis to leave exposed the neonate during its care. The inside of the thermal ring includes circular heaters surrounding said ring. Inside the cabin there is a closed recipient with water that takes advantage of the heat of said bubble to humidify air passing through the inlet door and outlet pipeline, which carry humidified and hot air to neonate. Furthermore, the equipment includes a water container, open at its upper part and placed out of the bubble, that allows simultaneously limiting the gas pressure of inspiration and expiration and the gas pressure of the neonate through two pipes.

Abstract: Equipment for the comprehensive care of high-risk newborns that ventilates, incubates, monitors and facilitates medical procedures.

Abstract: A method to linearly measure the flow of a gas in ducts, and a gas flow sensor using such a method are disclosed. In order to obtain a linear ratio between the differential pressure and the volumetric flow of a gas, a rectangular section elbow and a rectangular flexible plate located inside the elbow are used. When the flow goes through the duct linearization is obtained by combining the resistance of the duct and a variable-area obstruction caused by the plate. With linearization, it is possible to expand the measurement range of the gas flow in one duct. The sensor developed is used especially for the measurement of respiratory flow in medical applications.

Abstract: A medical device is provided for improving the intensive care of high-risk newborns. The device comprises a tempered air closed circuit enclosing a neonatal capsule and comprising a dome composed of two concentric layers defining an intra-dome space therebetween, through which tempered air can circulate, to maintain the temperature in the intermediate artificial environment created between the neonatal capsule and the tempered air closed circuit. A continuous ventilation circuit is provided comprising air and oxygen inlet lines and a mixture outlet line, to administer a continuous and regulated air flow of filtered, oxygenated, tempered and humidified air to the newborn child inside the neonatal capsule. A set of doors may be provided through the neonatal capsule and dome, to provide access inside the neonatal capsule.

Abstract: A method to linearly measure the flow of a gas in ducts, and a gas flow sensor using such a method are disclosed. In order to obtain a linear ratio between the differential pressure and the volumetric flow of a gas, a rectangular section elbow and a rectangular flexible plate located inside the elbow are used. When the flow goes through the duct linearization is obtained by combining the resistance of the duct and a variable-area obstruction caused by the plate. With linearization, it is possible to expand the measurement range of the gas flow in one duct. The sensor developed is used especially for the measurement of respiratory flow in medical applications.

Abstract: A medical device is provided for improving the intensive care of high-risk newborns. The device comprises a tempered air closed circuit enclosing a neonatal capsule and comprising a dome composed of two concentric layers defining an intra-dome space therebetween, through which tempered air can circulate, to maintain the temperature in the intermediate artificial environment created between the neonatal capsule and the tempered air closed circuit. A continuous ventilation circuit is provided comprising air and oxygen inlet lines and a mixture outlet line, to administer a continuous and regulated air flow of filtered, oxygenated, tempered and humidified air to the newborn child inside the neonatal capsule. A set of doors may be provided through the neonatal capsule and dome, to provide access inside the neonatal capsule.

Abstract: A process and an apparatus for producing substantially pure carbon dioxide from a carbon dioxide feed containing from about 80% to about 95% volume of carbon dioxide.

Abstract: A catalytic stove is provided comprising a mixing chamber having one end adapted to receive a fuel can and an opposite end provided with a diffuser. A plate provided with a grid of between 200 and 400 openings per square inch extends across the exit end of the diffuser. A catalytic surface is coated on the exit portion of the plate. The catalyst is selected from the group consisting of platinum, palladium, rhodium and iridium.