Patents by Inventor Claudio Cavazza

Claudio Cavazza has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Composition comprising a carnitine and glutathione, useful to increase the absorption of glutathione and synergize its effects
    Patent number: 6306392
    Abstract: A composition useful for increasing the absorption of glutathione and for synergizing its effects. This composition may take the form of a dietary supplement, dietetic support or of an actual medicine and comprises: (a) propionyl L-carnitine or a pharmacologically acceptable salt thereof; (b) glutathione or a glutathione-containing yeast; (c) a glutathione-free yeast if the component (b) consists of glutathione. The invention is also directed to methods of making this composition as well as to methods of prevention or treatment using it.
    Type: Grant
    Filed: December 15, 2000
    Date of Patent: October 23, 2001
    Assignee: Sigma-Tau Healthscience S.p.A.
    Inventor: Claudio Cavazza
  • Medicament and therapeutical method for treating idiopathic asthenozoospermia
    Publication number: 20010018455
    Abstract: A therapeutical method is disclosed for treating idiopathic asthenozoospermia which comprises orally or parenterally administering to a patient in need thereof a combination preparation comprising in admixture L-carnitine and acetyl L-carnitine or the pharmacologically acceptable salts thereof, in substantially equimolar amouts.
    Type: Application
    Filed: April 5, 2001
    Publication date: August 30, 2001
    Applicant: Sigma-Tau HealthScience, S.p.A.
    Inventor: Claudio Cavazza
  • Composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics and preventing the abuse of alcohol in healthy subjects
    Patent number: 6255346
    Abstract: A combination composition comprising L-carnitine, acetyl L-carnitine and propionyl L-carnitine or the pharmacologically acceptable salts thereof is disclosed which can be used as a pharmaceutical composition for suppressing withdrawal symptoms and craving for alcohol in alcoholics, and as a dietary supplement, health food, medical food or nutraceutical for preventing the abuse of alcohol in substantially healthy subjects, particularly in young individuals.
    Type: Grant
    Filed: June 6, 2000
    Date of Patent: July 3, 2001
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Aldo Fassi, Claudio Cavazza
  • Nutritional supplement for facilitating skeletal muscle adaptation to strenuous exercise and counteracting defatigation in asthenic individuals
    Patent number: 6245378
    Abstract: A nutritional supplement for facilitating the adaptation of skeletal muscle in individuals udergoing programs of strenuous exercise and counteracting defatigation and weariness in asthenic individuals is disclosed, which comprises a combination of L-camitine, acetyl L-camitine and propionyl L-carnitine as basic active ingredients. Optional ingredients comprise isovaleryl L-carnitine, branched-chained aminoacids and creatine and/or phosphocreatine.
    Type: Grant
    Filed: November 30, 1998
    Date of Patent: June 12, 2001
    Assignee: Sigma-Tau Healthscience S.p.A.
    Inventor: Claudio Cavazza
  • Medicament and therapeutical method for treating idiopathic asthenozoospermia
    Patent number: 6235784
    Abstract: A therapeutical method is disclosed for treating idiopathic asthenozoospermia which comprises orally or parenterally administering to a patient in need thereof a combination preparation comprising in admixture L-carnitine and acetyl L-carnitine or the pharmacologically acceptable salts thereof, in substantially equimolar amouts.
    Type: Grant
    Filed: August 12, 1998
    Date of Patent: May 22, 2001
    Assignee: Sigma-Tau HealthScience S.p.A.
    Inventor: Claudio Cavazza
  • Pharmaceutical composition comprising carnitine or alkanoyl L-carnitine, for the prevention and treatment of diseases brought about by lipid metabolism disorders
    Patent number: 6217898
    Abstract: A pharmaceutical compositions comprising L-carnitine or alkanoyl L-carnitine and hydroxycitric or pantothenic acid or derivatives thereof for the prevention and treatment of diseases brought about by lipid metabolism disorders, is disclosed.
    Type: Grant
    Filed: March 17, 1998
    Date of Patent: April 17, 2001
    Assignee: Sigma-Tau HealthScience S.p.A.
    Inventor: Claudio Cavazza
  • Composition comprising ketanserin and L-carnitine or an alkanoyl L-carnitine for the treatment of CRPS
    Patent number: 6214884
    Abstract: This invention relates to L-carnitine and lower alkanoyl L-carnitines in combination with ketanserin, for the therapeutic treatment of Chronic Regional Pain Syndrome (CRPS).
    Type: Grant
    Filed: December 10, 1999
    Date of Patent: April 10, 2001
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Claudio Cavazza, Menotti Calvani
  • Pharmaceutical compositions comprising alkanoyl L-carnitine in combination with a statine for treating pathologies brought about by an altered lipid metabolism
    Patent number: 6180680
    Abstract: Coordinated use of an alkanoyl L-carnitine such as propionyl L-carnitine and a statin such as simvastatin is described for treating pathologies resulting from altered lipid metabolism. Coordinated use of the two ingredients is achieved by substantial contemporaneous co-administration of the two active ingredients or by administering a combination composition containing a mixture of the two active ingredients.
    Type: Grant
    Filed: December 28, 1999
    Date of Patent: January 30, 2001
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Claudio Cavazza
  • Use of alkanoyl L-carnitines for the therapeutical treatment of chronic inflammatory bowel disease
    Patent number: 6143785
    Abstract: The use of lower alkanoyl L-carnitines is disclosed for preparing pharmaceutical compositions (particularly foams and enemas) for treating chronic inflammatory bowel diseases, in particular ulcerative colitis.
    Type: Grant
    Filed: November 16, 1999
    Date of Patent: November 7, 2000
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Claudio Cavazza
  • Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans
    Patent number: 6090848
    Abstract: A method is disclosed for treating idiopathic asthenozoospermia and improving sperm quality which comprises orally or parenterally administering to a subject in need thereof a combination preparation comprising either an admixture of or separately packaged L-carnitine and acetyl L-carnitine, or a pharmacologically acceptable salt thereof, in molar ratios ranging from about 4.0:1 to 1:1.5.
    Type: Grant
    Filed: July 28, 1998
    Date of Patent: July 18, 2000
    Assignee: Sigma-Tau Healthscience S.p.A.
    Inventor: Claudio Cavazza
  • Method for decreasing the appetite in bulimic, overweight individuals
    Patent number: 6066664
    Abstract: A method for controlling and decreasing the appetite in an overweight individual is disclosed which comprises administering to said individual 5-hydroxytryptophan and an alkanoyl L-carnitine wherein the alkanoyl group has 2-6 carbons atoms, preferably acetyl L-carnitine, or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: June 6, 1997
    Date of Patent: May 23, 2000
    Assignee: SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Claudio Cavazza
  • Medical food for diabetics
    Patent number: 6063820
    Abstract: A medical food for diabetics is disclosed which comprises as characterizing active ingredients .gamma.-linolenic acid and at least one alkanoyl-L-carnitine, e.g. acetyl-L-carnitine and/or propionyl-L-carnitine.
    Type: Grant
    Filed: March 18, 1998
    Date of Patent: May 16, 2000
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Claudio Cavazza
  • Use of alkanoyl L-carnitines for the therapeutical treatment of chronic inflammatory bowel diseases
    Patent number: 6013670
    Abstract: The present invention relates to a therapeutic use of the lower alkanoyl L-carnitines and the pharmacologically acceptable salts thereof in pharmaceutical compositions for the treatment of ulcerative colitis.
    Type: Grant
    Filed: June 4, 1997
    Date of Patent: January 11, 2000
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Claudio Cavazza
  • L-carnitine or derivatives thereof and antioxidants for the prevention and treatment of diseases elicited by oxidative stress to the nervous and cardiovascular system
    Patent number: 5998474
    Abstract: Therapeutic use is described of L-carnitine, alkanoyl L-carnitines and pharmacologically acceptable salts thereof, in combination with hydrophilic antioxidants or lipophilic antioxidants for the prevention or treatment of a disturbance or disease elicited by oxidative stress.
    Type: Grant
    Filed: March 18, 1997
    Date of Patent: December 7, 1999
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Claudio Cavazza
  • Use of lower alkanoyl L-carnitines to produce a medicament suitable for the therapeutic treatment of retinopathies
    Patent number: 5883127
    Abstract: The use of lower alkanoyl L-carnitines (e.g. acetyl L-carnitine) and the pharmacologically acceptable salts thereof to produce a medicament suitable for the therapeutic treatment of retinopathies, e.g. the age-related maculopathy (ARM) and non-age-related maculopathy (nARM), is disclosed.
    Type: Grant
    Filed: November 25, 1997
    Date of Patent: March 16, 1999
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A
    Inventor: Claudio Cavazza
  • Therapeutical method for the treatment of attention-deficit/hyperactive disorders
    Patent number: 5869528
    Abstract: A therapeutical method for the treatment of Attention-Deficit/Hyperactive Disorder (ADHD) is disclosed which comprises administering to a child in need thereof L-carnitine or an alkanoyl L-carnitine or a pharmacologically acceptable salt thereof.
    Type: Grant
    Filed: July 22, 1997
    Date of Patent: February 9, 1999
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Claudio Cavazza
  • Medicament and therapeutical method for treating idiopathic asthenozoospermia
    Patent number: 5863940
    Abstract: A therapeutical method is disclosed for treating idiopathic asthenozoospermia which comprises orally or parenterally administering to a patient in need thereof a combination preparation comprising in admixture L-carnitine and acetyl L-carnitine or the pharmacologically acceptable salts thereof, in substantially equimolar amouts.
    Type: Grant
    Filed: December 1, 1997
    Date of Patent: January 26, 1999
    Assignee: Sigma-Tau HealthScience S.p.A.
    Inventor: Claudio Cavazza
  • Compositions containing L-carnitine or an acyl L-carnitine in combination with an ace-inhibitor for the treatment of cardiovascular disorders and a method for treating cardiovascular disorders
    Patent number: 5861434
    Abstract: Compositions containing (a) L-carnitine, an acyl L-carnitine, or a pharmacologically acceptable salt thereof in combination with (b) an ACE-inhibitor are useful for treating cardiovascular disorders. Orally, parenterally, rectally or transdermally administrable pharmaceutical compositions in unit dosage form contain from about 0.5 to about 2 g of L-carnitine, or an equimolar amount of an acyl L-carnitine or a pharmacologically acceptable salt thereof, and, e.g., from about 5 to about 20 mg of the ACE-inhibitor lisinopril.
    Type: Grant
    Filed: March 8, 1996
    Date of Patent: January 19, 1999
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Claudio Cavazza
  • Pharmaceutical composition comprising L-carnitine or an alkanoyl L-carnitine in combination with a polyunsaturated fatty acid of the omega-3 series for the prevention and the treatment of lipid metabolism disorders
    Patent number: 5753703
    Abstract: A novel therapeutic use of L-carnitine or alkanoyl L-carnitine is disclosed in combination with a polyunsaturated fatty acid of the omega-3 series, for the prevention and the treatment of lipid metabolism disorders and cardiovascular disorders.
    Type: Grant
    Filed: November 22, 1996
    Date of Patent: May 19, 1998
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventors: Claudio Cavazza, Menotti Calvani
  • Pharmaceutical composition comprising L-carnitine or derivative thereof and trihydroxy or tetrahydroxystilbene
    Patent number: 5747536
    Abstract: The coordinated therapeutic use of L-carnitine, lower alkanoyl L-carnitines or the pharmacologically acceptable salts thereof with resveratrol, resveratrol derivatives or resveratrol-containing natural products is disclosed for producing a medicament for the prophylaxis and treatment of cardiovascular disorders, peripheral vascular diseases and peripheral diabetic neuropathy.
    Type: Grant
    Filed: October 2, 1996
    Date of Patent: May 5, 1998
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Claudio Cavazza