Abstract: Methods for isolating proteins from a honey sample are provided. The methods include contacting the honey sample with a substrate functionalized with one or more reactive dyes and recovering proteins associated with the substrate. Methods for detecting proteins in a honey sample and assessing the risk of colony collapse disorder are also provided.

Abstract: Methods for isolating proteins from a honey sample are provided. The methods include contacting the honey sample with a substrate functionalized with one or more reactive dyes and recovering proteins associated with the substrate. Methods for detecting proteins in a honey sample and assessing the risk of colony collapse disorder are also provided.

Abstract: Methods and kits for identifying neurological conditions in a patient by determining a level of expression of dynactin subunit p62 are disclosed. The neurological conditions may include, for example, Alzheimer's Disease (AD) without cerebral amyloid angiopathy (CAA).

Abstract: The invention relates to a one-step chemical composition that preserves animal tissue, cells, and biomolecules, such as human tissue, human cells, and biomolecules therein. It improves the fidelity and morphologic structure of cells, organelles, and nuclear chromatin, and maintains and enhances the cellular antigenicity for immunohistochemistry and flow cytometry, while preserving proteins, post-translational modifications of proteins, and nucleic acids. In one embodiment, the composition comprises a) a non-aldehyde precipitating fixative at a concentration below 25% (volume/volume), b) a reversible/cleavable protein cross-linker that targets lipid-associated molecules, and c) a c reversible/cleavable protein cross-linker that targets water soluble molecules. In another embodiment, the composition further includes a kinase inhibitor, a phosphatase inhibitor, and a permeation enhancer.

Abstract: In an embodiment of the invention, analytical data may be extracted from a business intelligence (BI) system on criteria specified in metadata of a business intelligence query. Once the data is extracted from the BI system, the extracted content may be provided in the context of semantic identifiers. In an embodiment, the semantic identifiers may provide a description of the extracted content associated with the identifier. In one embodiment, the semantic identifiers may be obtained from the criteria specified in the query. In another embodiment, the semantic identifiers may be defined in and obtained from a separate enterprise service repository. In an embodiment, a proposed mapping between query elements and semantic identifiers may be suggested by a processor.

Abstract: Methods and kits for identifying and/or monitoring neurological conditions in a patient using ratios of biomarkers are disclosed. The neurological conditions may include, for example, Alzheimer's disease or mild cognitive impairment. The particular biomarkers that may be useful in identifying and/or monitoring neurological conditions may include, for example, biliverdin reductase, biliverdin reductase, estrogen receptor alpha, superoxide dismutase, S100A7, hemeoxygenase 1, matrix metalloproteinase 9 and platelet derived growth factor receptor. In particular, ratios of these biomarkers are useful.

Abstract: In an embodiment of the invention, analytical data may be extracted from a business intelligence (BI) system on criteria specified in metadata of a business intelligence query. Once the data is extracted from the BI system, the extracted content may be provided in the context of semantic identifiers. In an embodiment, the semantic identifiers may provide a description of the extracted content associated with the identifier. In one embodiment, the semantic identifiers may be obtained from the criteria specified in the query. In another embodiment, the semantic identifiers may be defined in and obtained from a separate enterprise service repository. In an embodiment, a proposed mapping between query elements and semantic identifiers may be suggested by a processor.

Abstract: A method includes, during execution of a first application program in which a user interacts with the application program, executing a launchpad service that invokes another application program. When a user interface of the first application program is refreshed, a state of the launchpad service is determined based on the refreshed user interface, and one or more launchpad control elements are displayed along with the user interface depending on the determined state of the launchpad service. When the launchpad control element is activated by an operator, execution of a second application program referenced by the activated control element is initiated and advanced to a processing stage determined by the activated control element.

Abstract: Glioblastoma multiforme biomarkers, methods, and compositions are provided. Methods of selecting a treatment for a patient with a brain neoplasm, including Glioblastoma multiforme, are provided. Methods of treating a patient at risk for Glioblastoma multiforme are provided.

Abstract: In an embodiment of the invention, analytical data may be extracted from a business intelligence (BI) system on criteria specified in metadata of a business intelligence query. Once the data is extracted from the BI system, the extracted content may be provided in the context of semantic identifiers. In an embodiment, the semantic identifiers may provide a description of the extracted content associated with the identifier. In one embodiment, the semantic identifiers may be obtained from the criteria specified in the query. In another embodiment, the semantic identifiers may be defined in and obtained from a separate enterprise service repository. In an embodiment, a proposed mapping between query elements and semantic identifiers may be suggested by a processor.

Abstract: In an embodiment of the invention, analytical data may be extracted from a business intelligence (BI) system on criteria specified in metadata of a business intelligence query. Once the data is extracted from the BI system, the extracted content may be provided in the context of semantic identifiers. In an embodiment, the semantic identifiers may provide a description of the extracted content associated with the identifier. In one embodiment, the semantic identifiers may be obtained from the criteria specified in the query. In another embodiment, the semantic identifiers may be defined in and obtained from a separate enterprise service repository. In an embodiment, a proposed mapping between query elements and semantic identifiers may be suggested by a processor.

Abstract: Low molecular weight (LMW) peptides have been discovered that are indicative of neurological conditions, such as Alzheimer's Disease (AD), cognitive impairment and brain microhemmorhages. Evaluating patient samples for the presence of such LMW peptides is an effective means of detecting neurological conditions and monitoring the progression of the disease. The LMW peptides are particularly useful in detecting neurological conditions during the early stages without invasive procedures.

Abstract: A method includes, during execution of a first application program in which a user interacts with the application program, executing a launchpad service that invokes another application program. When a user interface of the first application program is refreshed, a state of the launchpad service is determined based on the refreshed user interface, and one or more launchpad control elements are displayed along with the user interface depending on the determined state of the launchpad service. When the launchpad control element is activated by an operator, execution of a second application program referenced by the activated control element is initiated and advanced to a processing stage determined by the activated control element.

Abstract: Methods, systems, apparatus and computer readable media are provided for managing data collection. In one implementation, a data collection initiative is implemented. Tasks associated with the data collection initiative are provided to participants, and information is received from the participants in response to the tasks. A status of the data collection initiative is provided based on the received information.