Abstract: The present invention relates to a balancing, positioning and fixating assembly for balancing a treatment device, comprising balance arm having a first arm end and a second arm end, a stepper part having a first part end and a second part end, the first arm end is connected with the second part end via a first pivot joint so that the balance arm is movable in relation to the stepper part, and an angulator device is arranged in connection with the second arm end, the angulator device is configured to connect the treatment device to the balance arm and to facilitate movement of the treatment device in different angles, wherein a spring device having a predetermined spring force is arranged along the balance arm, the spring device has a first spring end and a second spring end.

Abstract: A method for producing ghee involves churning cream to form butter and buttermilk, which is melted and heated to a temperature of 45° C. and 90° C. Phase inversion by shearing is performed to form an oil, which is concentrated by centrifugal separation into an oil fraction and a serum fraction. The oil faction is boiled and at least one milk product is supplied. The boiled oil is clarified to produce ghee having a fat content of at least 99.0 wt. %.

Abstract: This invention relates to novel benzisoxazole derivatives that are found to be potent modulators of potassium channels and, as such, are valuable candidates for the treatment of diseases or disorders as diverse as those which are responsive to the modulation of potassium channels e.g. a respiratory disease, epilepsy or convulsions. X represents a substituent selected from the group consisting of CO—NR?R?, CO—O—R?, CO—NH—S, CO—NH—SO2R??, CO—NH—C?N, SO2—NR?R?, 2,3-dihydro-1-H-tetrazol-5-yl and [1,2,4]oxadiazolidin-5-one; wherein R? and R?, independently of each other, represent hydrogen or alkyl or phenyl; and R?? represents alkyl, cycloalkyl, haloalkyl or phenyl, which phenyl may optionally be substituted one or more times with substituents selected from halo, trifluoromethyl, trifluoromethoxy, cyano and nitro.

Abstract: This invention relates to pharmaceutical compositions comprising a combination of an AMPA/kainate antagonistic compound and an inhibitor of a multidrug resistance protein and its use for combating epileptic disorders.

Abstract: The invention provides novel compounds represented by the general formula compound represented by the formula: wherein the bond represented by the broken line may be a single, a double bond or absent; and if the bond is absent, then the nitrogen is substituted with a hydrogen and R2; X represents SO2 or C?O or CH2; Y represents —CH(R4)—, —N(R4)— or —N(R4)—CH2—, O; and the meaning of R2, R3, R4, R5, R6, R7, and R8 are as defined in the application The compounds are useful as positive modulators of the AMPA-receptor.

Abstract: This invention relates to novel benzothiazine derivatives of Formula I useful as modulators of the AMPA sensitive glutamate receptors, pharmaceutical compositions comprising such compounds and their use in therapy.

Abstract: The invention provides novel compounds represented by general formula (I) wherein the bond represented by the broken line may be a single, double bond or absent; and if the bond is absent, then the nitrogen is substituted with a hydrogen and R2; X represents SO2 or C?O of CH2; Y represents —CH(R4)—, —N(R4)—CH2—, O; and the meaning of R2, R3, R4, R5, R6, R7, and R8 are as defined in the application. The compounds are useful as positive modulators of the AMPA-receptor.

Abstract: This invention relates to novel benzothiazine derivatives of Formula I useful as modulators of the AMPA sensitive glutamate receptors, pharmaceutical compositions comprising such compounds and their use in therapy.

Abstract: The invention provides novel compounds represented by the general formula 5 compound represented by the formula: 1