Abstract: A vehicle, such as a rail vehicle, has an electrodynamic braking apparatus with at least one brake resistor. The at least one brake resistor forms a portion of the vehicle body shell that is permanently closed and over which air flows on the exterior, in particular, during travel of the vehicle. In the alternative, the brake resistor is arranged in the immediate vicinity of the permanently closed portion. The brake resistor conducts away heat outwardly to the environment via the permanently closed portion. There is also described a brake resistor for a vehicle, in particular for a rail vehicle, which is configured accordingly.

Abstract: A vehicle, such as a rail vehicle, has an electrodynamic braking apparatus with at least one brake resistor. The at least one brake resistor forms a portion of the vehicle body shell that is permanently closed and over which air flows on the exterior, in particular, during travel of the vehicle. In the alternative, the brake resistor is arranged in the immediate vicinity of the permanently closed portion. The brake resistor conducts away heat outwardly to the environment via the permanently closed portion. There is also described a brake resistor for a vehicle, in particular for a rail vehicle, which is configured accordingly.

Abstract: A semi-recombinant method for the production of GLP-1 analogues and derivatives with non-proteogenic amino acids in the N-terminal part combining the use of recombinant expression techniques and chemical peptide synthesis.

Abstract: The disclosure relates to a sieve mill including a basket having a curved inner side for supporting a sieve which rests on the curved inner side of the sieve basket, and two longitudinal edges which are parallel and opposite each other, a material inlet arranged above the sieve and a cylindrical rotor arranged such that it can rotate inside the sieve basket. A longitudinal edge of the sieve is arranged in a first retaining bar having a first positioning recess for receiving the longitudinal edge, and another longitudinal edge is arranged in a second retaining bar having a second positioning recess for receiving the other longitudinal edge, the second retaining bar can pivot between an open position in which the second positioning recess can withdraw and feed the associated longitudinal edge, and a closed position in which the second positioning recess exerts pressure upon the longitudinal edge.

Abstract: The invention relates to a device having two rotational shafts which are arranged at least essentially parallel to each other and associated with rotational axes (13a, 15a) separated by means of an adjustable distance. The shafts extend respectively through a wall (28) which separates a drive side from the product side, and are sealed with respect to the wall (28).

Abstract: The invention relates to a sieve mill (10) comprising a basket (12) having a curved inner side for supporting a sieve (14) which rests on the curved inner side of the sieve basket (12), and two longitudinal edges (32, 34) which are parallel and opposite each other, also comprising a material inlet (18) arranged above the sieve (14) and a cylindrical rotor (16) which is arranged such that it can rotate inside the sieve basket (12).

Abstract: A semi-recombinant method for the production of GLP-1 analogues and derivatives with non-proteogenic amino acids in the N-terminal part combining the use of recombinant expression techniques and chemical peptide synthesis.

Abstract: A method for preparing a compound of formula I or a salt thereof is disclosed.

Abstract: The present invention relates to novel polymorphic/pseudopolymorphic forms of 6-Chloro-3-(1-methylcyclopropyl)amino-4H-thieno[3,2-e]-1,2,4-thiadiazine 1,1-dioxide or mixtures thereof, their preparation and their use as therapeutic agents.

Abstract: This invention relates to (2R,3R,4R)-3,4-dihydroxy-2-hydroxymethylpyrrolidine D-tartrate, preparation thereof and use as therapeutic agent.

Abstract: The compounds disclosed are salts of (2E)-5-amino-5-methylhex-2-enoic acid N-methyl-N-((1R)-1-(N-methyl-N-((1R)-1-(methylcarbamoyl)-2-phenylethyl)carbamoyl)-2-(2-naphthyl)ethyl)amide of Formula I which have an aqueous solubility of at least 5 mg/ml, and a hygroscopicity of less than about 8 at 98% RH. These compounds are useful in the treatment of growth hormone deficiency.

Abstract: A new salt of (2R,3R,4R)-3,4-dihydroxy-2-hyroxymethylpyrrolidine is disclosed. Specifically, (2R,3R,4R-3,4-dihydroxy-2-hydroxymethylpyrrolidine, 2-naphthalenesulfonate is disclosed, as well as its preparation and use for treating and preventing diabetes and obesity and for regulating appetite. This salt is characterized as having a high melting point and low hygroscopicity.

Abstract: Caprolactam is purified by oxidative treatment in which mixtures which essentially contain the caprolactam to be purified and unsaturated lactams are treated with oxygen or an oxygen-containing gas mixture in an alkaline medium.

Abstract: Caprolactam is obtained from caprolactam-containing polymers in the presence of a base under reduced pressure by depolymerizing polymers which contain the repeating unit --[--N(H)--(CH.sub.2).sub.5 --C(O)--] or mixtures consisting essentially offrom 50 to 99.99% by weight of a polymer containing the repeating unit --[--N(H)--(CH.sub.2).sub.5 --C(O)--]--from 0.01 to 50% by weight of additives selected from the group consisting of inorganic fillers, organic and inorganic pigments and dyes,from 0 to 10% by weight of organic and/or inorganic additives,from 0 to 40% by weight of non-polyamide-containing polymers andfrom 0 to 20% by weight of polyamides, with the exception of polycaprolactam and copolyamides prepared from caprolactam,in at least two depolymerization reactors connected in series.

Abstract: Caprolactam is obtained from mixtures which contain polymers or thermoplastic molding materials having the repeating unit--N(H)--(CH.sub.2).sub.5 --C(O)--(a) by cleavage at elevated temperatures in the presence of a base under reduced pressure or (b) in the presence of water, by using a mixture essentially comprisingfrom 50 to 99.9% by weight of a polymer or of a thermoplastic molding material having the repeating unit--N(H)--(CH.sub.2).sub.5 --C(O)--from 0.1 to 50% by weight of additives selected from the group consisting of inorganic fillers, organic and inorganic pigments and dyes,from 0 to 10% by weight of organic and/or inorganic additives,from 0 to 40% by weight of non-polyamide-containing polymers andfrom 0 to 20% by weight of polyamides, with the exception of polycaprolactam and copolyamides prepared from caprolactam,and carrying out the cleavage in the presence of a base under reduced pressure, the water content of the mixture used being not more than 0.

Abstract: A process for the preparation of aminopropionitriles of the general formula I ##STR1## in which R denotes hydrogen or methyl, wherein ammonia is caused to react with an acrylonitrile of the general formula II ##STR2## In which the substituent has the aforementioned meanings, in a molar ratio of from 1:1 to 500:1 over a heterogenic catalyst at temperatures ranging from 40.degree. to 180.degree. C. and pressures ranging from 10 to 350 bar.

Abstract: A process for the preparation of 3-aminomethyl-3,5,5-trimethyl-cyclohexylamine from 3-cyano-3,5,5-trimethyl-cyclohexanone, wherein the following stages are carried out in discrete reaction chambers:a) the 3-cyano-3,5,5-trimethyl-cyclohexanone is reacted in a first reaction chamber with excess ammonia over an acidic metal oxide catalyst at a temperature of from 20.degree. to 150.degree. C. and a pressure of from 15 to 500 bar, andb) in a second reaction chamber, the reaction product from stage a) is hydrogenated with hydrogen at a temperature of from 60.degree. to 150.degree. C. and a pressure of from 50 to 300 bar in the presence of excess ammonia over a catalyst containing cobalt, nickel, ruthenium, and/or some other noble metal, which catalyst optionally contains a basic component or is supported by neutral or basic supporting material.

Abstract: A process for recovering caprolactam from oligomers and/or polymers of caprolactam comprises the following steps:a) treating oligomers and/or polymers of caprolactam with from 1 to 20 parts by weight of water per part by weight of oligomer or polymer at from 200.degree. to 350.degree. C. under superatmospheric pressure with a residence time of from 0.5 to 10 hours to form an aqueous reaction mixture comprising polycaprolactam, monomeric caprolactam and oligomers thereof, andb) passing the aqueous reaction mixture obtained in a) into a fluidized bed of alumina at from 250.degree. to 400.degree. C. to obtain a mixture of steam and caprolactam.

Abstract: Caprolactam is recovered from polycaprolactam by hydrolyric cleavage of polycaprolactam with from 5 to 50 parts by weight of water per part by weight of polycaprolactam at from 200.degree. to 350.degree. C. under superatmospheric pressure to give an aqueous solution or suspension which contains monomeric caprolactam and oligomers thereof and may contain polycaprolactam and subsequent isolation of monomeric caprolactam from the aqueous solution or suspension by distillation or extraction, by a process in which the hydrolyric cleavage is carried out in the presence of an alkali metal hydroxide at a pH of from 5 to 10.

Abstract: Caprolactam is purified by oxidative treatment in which mixtures which essentially contain the caprolactam to be purified and unsaturated lactams are treated with oxygen or an oxygen-containing gas mixture in an alkaline medium.