Patents by Inventor Clay Beauregard

Clay Beauregard has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BICYCLIC HETEROARYL INHIBITORS OF PDE4
    Publication number: 20130045975
    Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators.
    Type: Application
    Filed: February 10, 2012
    Publication date: February 21, 2013
    Applicant: KALYPSYS, INC.
    Inventors: Steven P. Govek, Clay Beauregard, Daniel A. Gamache, Mark R. Hellberg, Stewart A. Noble, Andrew K. Shiau, David J. Thomas, John M. Yanni
  • Heteroarylalkoxy-substituted quinolone inhibitors of PDE4
    Patent number: 8138205
    Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators.
    Type: Grant
    Filed: August 19, 2009
    Date of Patent: March 20, 2012
    Assignee: Kalypsys, Inc.
    Inventors: Steven P. Govek, Clay Beauregard, Daniel A. Gamache, Mark R. Hellberg, Stewart A. Noble, Andrew K. Shiau, David J. Thomas, John M. Yanni
  • HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE
    Publication number: 20120065187
    Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.
    Type: Application
    Filed: November 21, 2011
    Publication date: March 15, 2012
    Applicants: ALCON RESEARCH, LTD, KALYPSYS, INC.
    Inventors: Allen J. Borchardt, Clay Beauregard, Travis Cook, Robert L. Davis, Daniel A. Gamache, John M. Yanni
  • METHODS AND COMPOSITIONS FOR THE TREATMENT OF ALLERGY
    Publication number: 20120015953
    Abstract: The present invention relates to compositions comprising an antagonist of the histamine H1 receptor and a compatible antagonist of the histamine H4 receptor. The antagonist compounds are selected to prevent the H4 receptor antagonist from interfering with the H1 receptor antagonist's suppression of acute phase allergic responses in a patient. The present invention also relates to compositions comprising a mast cell stabilizer and a compatible antagonist of the histamine H4 receptor.
    Type: Application
    Filed: July 14, 2011
    Publication date: January 19, 2012
    Inventors: Clay Beauregard, Peter G. Klimko, John M. Yanni, Daniel A. Gamache
  • HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE
    Publication number: 20110257137
    Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.
    Type: Application
    Filed: March 10, 2011
    Publication date: October 20, 2011
    Applicant: KALYPSYS, INC.
    Inventors: Allen Borchardt, Robert Davis, Clay Beauregard, Daniel Becker, Daniel Gamache, Stewart A. Noble, Mark Hellberg, Peter Klimko, Zhihai Qiu, Joseph Payne, John Yanni
  • Method of treating ocular allergy
    Patent number: 8034839
    Abstract: The topical use of 5,6,7-trihydroxyheptanoic acid and analogs alone or in combination with histamine antagonists and/or mast cell stabilizers is disclosed for the treatment of ocular allergy.
    Type: Grant
    Filed: February 8, 2010
    Date of Patent: October 11, 2011
    Assignee: Alcon Research, Ltd.
    Inventors: Peter G. Klimko, Clay Beauregard
  • HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE
    Publication number: 20110237599
    Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.
    Type: Application
    Filed: March 9, 2011
    Publication date: September 29, 2011
    Applicant: Kalypsys, Inc.
    Inventors: Allen Borchardt, Robert Davis, Clay Beauregard, Daniel Gamache, Mark Hellberg, Peter Klimko, John Yanni
  • METHOD OF TREATING OCULAR ALLERGY
    Publication number: 20100160298
    Abstract: The topical use of 5,6,7-trihydroxyheptanoic acid and analogs alone or in combination with histamine antagonists and/or mast cell stabilizers is disclosed for the treatment of ocular allergy.
    Type: Application
    Filed: February 8, 2010
    Publication date: June 24, 2010
    Applicant: Alcon Research, Ltd.
    Inventors: Peter G. Klimko, Clay Beauregard
  • HETEROCYCLIC INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE
    Publication number: 20100120741
    Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.
    Type: Application
    Filed: September 10, 2009
    Publication date: May 13, 2010
    Applicants: Kalypsys, Inc., Alcon Research, Ltd
    Inventors: Allen J. Borchardt, Clay Beauregard, Travis Cook, Robert L. Davis, Daniel A. Gamache, John M. Yanni
  • BICYCLIC HETEROARYL INHIBITORS OF PDE4
    Publication number: 20100081646
    Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of phosphodiesterase 4 (PDE4) for the treatment or prevention of inflammatory diseases and other diseases involving elevated levels of cytokines and proinflammatory mediators.
    Type: Application
    Filed: August 19, 2009
    Publication date: April 1, 2010
    Applicant: KALYPSYS, INC.
    Inventors: Steven P. Govek, Clay Beauregard, Daniel A. Gamache, Mark R. Hellberg, Stewart A. Noble, Andrew K. Shiau, David J. Thomas, John M. Yanni
  • Method of treating ocular allergy
    Patent number: 7687539
    Abstract: The topical use of 5,6,7-trihydroxyheptanoic acid and analogs alone or in combination with histamine antagonists and/or mast cell stabilizers is disclosed for the treatment of ocular allergy.
    Type: Grant
    Filed: November 7, 2006
    Date of Patent: March 30, 2010
    Assignee: Alcon Research, Ltd.
    Inventors: Peter G. Klimko, Clay Beauregard
  • AMINOPYRIMIDINE INHIBITORS OF HISTAMINE RECEPTORS FOR THE TREATMENT OF DISEASE
    Publication number: 20100063047
    Abstract: The present invention relates to compounds and methods which may be useful as inhibitors of H1R and/or H4R for the treatment or prevention of inflammatory, autoimmune, allergic, and ocular diseases.
    Type: Application
    Filed: September 10, 2009
    Publication date: March 11, 2010
    Applicants: KALYPSYS, INC., ALCON RESEARCH, LTD
    Inventors: Allen J. Borchardt, Clay Beauregard, Robert L. Davis, Daniel A. Gamache, John M. Yanni
  • USE OF A COMBINATION OF OLOPATADINE AND CILOMILAST TO TREAT NON-INFECTIOUS RHINITIS AND ALLERGIC CONJUNCTIVITIS
    Publication number: 20090182035
    Abstract: Disclosed are methods of treating allergic conjunctivitis and non-infectious rhinitis in a subject that involve topically administering to the subject a composition comprising olopatadine and cilomilast.
    Type: Application
    Filed: March 18, 2009
    Publication date: July 16, 2009
    Applicant: Alcon Research, Ltd.
    Inventors: John M. Yanni, Daniel A. Gamache, Steven T. Miller, Clay Beauregard
  • METHOD OF TREATING ASTHMA, ALLERGIC RHINITIS, AND SKIN DISORDERS
    Publication number: 20090156667
    Abstract: The use of 5,6,7-trihydroxyheptanoic acid and analogs is disclosed for the treatment of asthma, allergic rhinitis, and skin disorders such as allergic dermatitis, contact hypersensitivity, urticaria (hives), rosacea, or psoriasis.
    Type: Application
    Filed: February 19, 2009
    Publication date: June 18, 2009
    Applicant: Alcon Research, Ltd.
    Inventors: Peter G. Klimko, Clay Beauregard, Bryon S. Severns
  • Use of an Inhibitor of TNFa Plus an Antihistamine to Treat Allergic Rhinitis and Allergic Conjunctivitis
    Publication number: 20080254029
    Abstract: Disclosed are methods of treating allergic conjunctivitis and allergic rhinitis in a subject that involve topically administering to the subject a composition comprising a pharmaceutically effective amount of an H1 antagonist and an anti-TNF? compound.
    Type: Application
    Filed: April 10, 2008
    Publication date: October 16, 2008
    Applicant: ALCON RESEARCH, LTD.
    Inventors: John M. Yanni, Daniel A. Gamache, Steven T. Miller, Clay Beauregard
  • Method of Treating Asthma, Allergic Rhinitis, and Skin Disorders
    Publication number: 20080108695
    Abstract: The use of 5,6,7-trihydroxyheptanoic acid and analogs is disclosed for the treatment of asthma, allergic rhinitis, and skin disorders such as allergic dermatitis, contact hypersensitivity, urticaria (hives), rosacea, or psoriasis.
    Type: Application
    Filed: November 6, 2007
    Publication date: May 8, 2008
    Applicant: Alcon Manufacturing Ltd.
    Inventors: Peter Klimko, Clay Beauregard, Bryon Severns