Abstract: A probe used to determine different possible body conditions of a human or animal subject includes an elongated insertable portion which is adapted for use orally, anally or vaginally, and along which are provided a number of biosensors and/or temperature sensors. The elongated portion is contoured so as to have a complementary shape to the physiology of the user's mouth, anus or vagina to ensure good contact between the probe sensors and the subject's body fluids or tissues. At least some of the sensors are positioned within a channel or trough which extends along the insertable portion of the probe and which is sized to collect body fluids from the subject therein. Preferably the channel is defined by a pair of spaced apart projecting ribs with fluid grooves formed in the elongated portion to assist in directing body fluids towards the channel and sensors.