Abstract: Embodiments described herein relate to a system for positioning indicator lights of a network device. The system may include a circuit board, which may include a circuit board edge positioned behind a front panel of the network device, two surfaces; and a side of the circuit board edge positioned between the two surfaces. The system may also include a hole through the circuit board near the circuit board edge, a cutout extending from a portion of the hole to the side of the circuit board edge, a LED coupled to the surface of the circuit board and adapted to emit light into the hole, and a lightpipe disposed in the hole to receive light emitted from the LED into a first end of the lightpipe. The lightpipe may direct the light from a second end of the lightpipe toward an opening in the front panel of the network device.

Abstract: Embodiments described herein relate to a system for positioning indicator lights of a network device. The system may include a circuit board, which may include a circuit board edge positioned behind a front panel of the network device, two surfaces; and a side of the circuit board edge positioned between the two surfaces. The system may also include a hole through the circuit board near the circuit board edge, a cutout extending from a portion of the hole to the side of the circuit board edge, a LED coupled to the surface of the circuit board and adapted to emit light into the hole, and a lightpipe disposed in the hole to receive light emitted from the LED into a first end of the lightpipe. The lightpipe may direct the light from a second end of the lightpipe toward an opening in the front panel of the network device.

Abstract: Disclosed herein, inter alia, are compounds and methods for inhibiting Taspase1 and the treatment of cancer.

Abstract: The present invention is directed to methods of inhibiting p97 and compounds and compositions useful in such methods. Diseases and conditions the can be treated with the compounds and compositions of the invention include, but are not limited to, cancer and neurodegenerative disorders susceptible to treatment by inhibition of p97.

Abstract: The present invention is directed to methods of inhibiting p97 and compounds and compositions useful in such methods. Diseases and conditions the can be treated with the compounds and compositions of the invention include, but are not limited to, cancer and neurodegenerative disorders susceptible to treatment by inhibition of p97.

Abstract: The present invention is directed to methods of inhibiting p97 and compounds and compositions useful in such methods. Diseases and conditions the can be treated with the compounds and compositions of the invention include, but are not limited to, cancer and neurodegenerative disorders susceptible to treatment by inhibition of p97.

Abstract: The present invention is directed to methods of inhibiting p97 and compounds and compositions useful in such methods. Diseases and conditions the can be treated with the compounds and compositions of the invention include, but are not limited to, cancer and neurodegenerative disorders susceptible to treatment by inhibition of p97.

Abstract: The present invention relates to novel N-cyanomethyl amides which are cysteine protease inhibitors, the pharmaceutically acceptable salts and N-oxides thereof, their uses as therapeutic agents and the methods of their making.

Abstract: Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit 5 HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as in assays for the detection of HIV protease.

Abstract: Methods are provided for identifying anti-HIV therapeutic compounds substituted with carboxyl ester or phosphonate ester groups. Libraries of such compounds are screened optionally using the novel enzyme GS-7340 Ester Hydrolase. Compositions and methods relating to GS-7340 Ester Hydrolase also are provided.

Abstract: Phosphonate substituted compounds with HIV protease inhibitory properties having use as therapeutics and for other industrial purposes are disclosed. The compositions inhibit HIV protease activity and/or are useful therapeutically for the treatment of AIDS and other antiviral infections, as well as in assays for the detection of HIV protease.

Abstract: A method for delivering polymerized therapeutic agents and their compositions are disclosed. The various polymers take advantage of the functional domains found in a variety of therapeutic agents. The polymerized therapeutic agent compositions are prepared by covalently linking the agent to a biocompatible backbone either directly or through backbone conjugates/monomers. The polymerized therapeutic agent compositions of the invention have highly desirable properties, which make them particularly well suited for use in biological and biomedical applications.

Abstract: A method and apparatus for applying a random, speckled pattern of dye to a moving web, such as carpeting. A series of closely spaced distributor units are mounted over the top surface of the web, and each carries a rotating disc, onto which dye material is flowed at a controlled rate. The rotating discs are formed with a highly irregular peripheral contour, such that a high degree of variability and randomness is imparted to the size and trajectory of the atomized dye particles. A significantly improved appearance of randomness in the speckled pattern is achieved.

Abstract: An elongated manifold is supplied with either foam or liquid under pressure through a plurality of inlet ports spaced along the manifold. The manifold contacts a curved blade along a line substantially parallel to, and below the elevation of, the crest of a horizontally disposed curved blade. The manifold is provided with outlet means above the line of contact whereby foam or liquid discharged from the manifold builds up behind the blade's crest until it overflows the crest to flow as a uniform film onto a web moving past an edge of the blade.

Abstract: Either foam or liquid is supplied under pressure to a distributor having a plurality of outlets each connected to a respective passageway extending along one side of a trough. Means are provided to combine the streams of material exiting the passageways prior to the material entering the trough. A curved blade is positioned along the opposite side of the trough. As the trough fills, an overflow of material passes over the crest of the blade and moves along the blade's curvature so as to be uniformly deposited on a web of material moving in a direction normal to the length of the trough.

Abstract: In the manufacture of tufted carpets from a sheet of yarns which are dyed along their lengths at different positions with different colors, mending yarns are provided at the edge of the sheet which are dyed in segments along their length using the same dye colors as the yarns in the sheet. The mending yarns are tufted into the selvedge of the carpet where they can be pulled out for use in mending the carpet when dropped stitches occur.