Patents by Inventor Clifford Berkman

Clifford Berkman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS
    Publication number: 20230144322
    Abstract: Compounds of Marlush formula (I) described in the claims are useful in diagnostic methods for detecting and/or identifying cells presenting PSMA. Disclosed are also methods for preparing the compounds.
    Type: Application
    Filed: January 4, 2023
    Publication date: May 11, 2023
    Inventors: Clifford Berkman, Svetlana A. Stekhova
  • 18F-labeled PSMA-targeted PET imaging agents
    Patent number: 11554183
    Abstract: Compounds of Marlush formula (I) described in the claims are useful in diagnostic methods for detecting and/or identifying cells presenting PSMA. Disclosed are also methods for preparing the compounds.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: January 17, 2023
    Assignees: CANCER TARGETED TECHNOLOGY LLC, WASHINGTON STATE UNIVERSITY
    Inventors: Clifford Berkman, Svetlana A. Stekhova
  • Chelated PSMA Inhibitors
    Publication number: 20220162241
    Abstract: Provided herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof. Also provided are compositions including a compound of Formula (I) together with a pharmaceutically acceptable carrier, and methods for imaging prostate cancer cells.
    Type: Application
    Filed: November 17, 2021
    Publication date: May 26, 2022
    Inventors: Clifford Berkman, Cindy Choy
  • Chelated PSMA inhibitors
    Patent number: 11225496
    Abstract: Provided herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof. Also provided are compositions including a compound of Formula (I) together with a pharmaceutically acceptable carrier, and methods for imaging prostate cancer cells.
    Type: Grant
    Filed: August 10, 2017
    Date of Patent: January 18, 2022
    Assignee: Cancer Targeted Technology LLC
    Inventors: Clifford Berkman, Cindy Choy
  • Albumin-binding PSMA inhibitors
    Patent number: 11147889
    Abstract: Provided herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein L1 and L2 are each independently a covalent bond or a divalent linking group, R is a detectable label or therapeutic drug and B is an albumin binding moiety. Also provided are compositions including a compound of Formula (I) together with a pharmaceutically acceptable carrier, and methods for imaging prostate cancer cells using a compound of Formula (I).
    Type: Grant
    Filed: November 24, 2017
    Date of Patent: October 19, 2021
    Assignee: Cancer Targeted Technology LLC
    Inventors: Clifford Berkman, Cindy Choy
  • Albumin-Binding PSMA Inhibitors
    Publication number: 20200061218
    Abstract: Provided herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof, wherein L1 and L2 are each independently a covalent bond or a divalent linking group, R is a detectable label or therapeutic drug and B is an albumin binding moiety. Also provided are compositions including a compound of Formula (I) together with a pharmaceutically acceptable carrier, and methods for imaging prostate cancer cells using a compound of Formula (I).
    Type: Application
    Filed: November 24, 2017
    Publication date: February 27, 2020
    Inventors: Clifford Berkman, Cindy Choy
  • Chelated PSMA Inhibitors
    Publication number: 20190309000
    Abstract: Provided herein are compounds of Formula (I) or a pharmaceutically acceptable salt thereof. Also provided are compositions including a compound of Formula (I) together with a pharmaceutically acceptable carrier, and methods for imaging prostate cancer cells.
    Type: Application
    Filed: August 10, 2017
    Publication date: October 10, 2019
    Inventors: Clifford Berkman, Cindy Choy
  • Chelated PSMA inhibitors
    Patent number: 10166301
    Abstract: Compounds as defined herein are provided which are useful in (1) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable diluent; and (3) methods for imaging prostate cancer cells.
    Type: Grant
    Filed: January 17, 2018
    Date of Patent: January 1, 2019
    Assignee: CANCER TARGETED TECHNOLOGY LLC
    Inventors: Clifford Berkman, Bea Langton-Webster, Xiaobing Wang
  • Chelated PSMA Inhibitors
    Publication number: 20180207298
    Abstract: Compounds as defined herein are provided which are useful in (1) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable diluent; and (3) methods for imaging prostate cancer cells.
    Type: Application
    Filed: January 17, 2018
    Publication date: July 26, 2018
    Inventors: Clifford Berkman, Bea Langton-Webster, Xiaobing Wang
  • Chelated PSMA inhibitors
    Patent number: 9974869
    Abstract: Compounds as defined herein are provided which are useful in (1) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable diluent; and (3) methods for imaging prostate cancer cells.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: May 22, 2018
    Assignee: Cancer Targeted Technology LLC
    Inventors: Clifford Berkman, Bea Langton-Webster, Xiaobing Wang
  • Chelated PSMA Inhibitors
    Publication number: 20170072075
    Abstract: Compounds as defined herein are provided which are useful in (1) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable diluent; and (3) methods for imaging prostate cancer cells.
    Type: Application
    Filed: August 24, 2016
    Publication date: March 16, 2017
    Inventors: Clifford Berkman, Bea Langton-Webster, Xiaobing Wang
  • Chelated PSMA inhibitors
    Patent number: 9446157
    Abstract: Compounds as defined herein are provided which are useful in (1) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable diluent; and (3) methods for imaging prostate cancer cells.
    Type: Grant
    Filed: June 13, 2012
    Date of Patent: September 20, 2016
    Assignee: Cancer Targeted Technology LLC
    Inventors: Clifford Berkman, Bea Langton-Webster, Xiaobing Wang
  • 18F-LABELED PSMA-TARGETED PET IMAGING AGENTS
    Publication number: 20160030605
    Abstract: Compounds of Marlush formula (I) described in the claims are useful in diagnostic methods for detecting and/or identifying cells presenting PSMA. Disclosed are also methods for preparing the compounds.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: Clifford Berkman, Svetlana A. Stekhova
  • Chelated PSMA Inhibitors
    Publication number: 20140241985
    Abstract: Compounds as defined herein are provided which are useful in (1) diagnostic methods for detecting and/or identifying cells presenting PSMA; (2) compositions comprising a compound of the invention together with a pharmaceutically acceptable diluent; and (3) methods for imaging prostate cancer cells.
    Type: Application
    Filed: June 13, 2012
    Publication date: August 28, 2014
    Applicant: CANCER TARGETED TECHNOLOGY LLC
    Inventors: Clifford Berkman, Bea Langton-Webster, Xiaobing Wang