Patents by Inventor Clifford J. Holmes

Clifford J. Holmes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8975240
    Abstract: Peritoneal dialysis solutions including a glucose polymer and methods of using the dialysis solutions are disclosed herein. In a general embodiment, the peritoneal dialysis solution includes a glucose polymer in an amount to provide an increased ultrafiltration fluid volume for a given amount of carbohydrate absorbed compared to conventional dialysis solutions containing icodextrin as the active pharmaceutical ingredient. The increased ultrafiltration fluid volume for a given amount of carbohydrate absorbed is obtained by providing specific combinations of weight-average molecular weight, polydispersity index and concentration of the glucose polymer in the dialysis solution.
    Type: Grant
    Filed: March 14, 2012
    Date of Patent: March 10, 2015
    Assignees: Baxter International Inc., Baxter Healthcare S.A.
    Inventors: John Kenneth Leypoldt, Clifford J. Holmes, Sujatha Karoor, Catherine M. Hoff, Leo Martis, Rahul Tandon
  • Publication number: 20120238525
    Abstract: Peritoneal dialysis solutions including a glucose polymer and methods of using the dialysis solutions are disclosed herein. In a general embodiment, the peritoneal dialysis solution includes a glucose polymer in an amount to provide an increased ultrafiltration fluid volume for a given amount of carbohydrate absorbed compared to conventional dialysis solutions containing icodextrin as the active pharmaceutical ingredient. The increased ultrafiltration fluid volume for a given amount of carbohydrate absorbed is obtained by providing specific combinations of weight-average molecular weight, polydispersity index and concentration of the glucose polymer in the dialysis solution.
    Type: Application
    Filed: March 14, 2012
    Publication date: September 20, 2012
    Applicants: BAXTER HEALTHCARE S.A., BAXTER INTERNATIONAL INC.
    Inventors: John Kenneth Leypoldt, Clifford J. Holmes, Sujatha Karoor, Catherine M. Hoff, Leo Martis, Rahul Tandon
  • Patent number: 5948385
    Abstract: An antimicrobial material incorporated with a molecular halogen is provided. The antimicrobial material includes a plastic material and a molecular halogen entrapped within the plastic material. A directional release material is also provided in the present application. The directional release material allows for the control of the rate and site of halogen release. Still further, method of impregnating a plastic material are also provided.
    Type: Grant
    Filed: September 30, 1997
    Date of Patent: September 7, 1999
    Assignee: Baxter International Inc.
    Inventors: John R. Chapman, Ying-Cheng Lo, Winnie Kubey, Clifford J. Holmes, David Bell