Patents by Inventor Clifton Ngan

Clifton Ngan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for the production of poly(methyl methacrylate) (PMMA) membranes and uses thereof
    Patent number: 10877029
    Abstract: A poly(methyl methacrylate) (PMMA) membrane having a highly porous, reticulated, 3-D structure suitable for lateral flow diagnostic applications is described. Also described is a method for producing a poly(methyl methacrylate) (PMMA) membrane that comprises the steps of mixing a suitable amount of PMMA, a solvent and a optionally one of either a co-solvent or a non-solvent to produce a solution, casting a thin film of the solution onto a support, and removal of the solvent from the solution to produce the PMMA membrane. A lateral flow diagnostic device comprising a highly porous PMMA membrane as a reaction membrane is also described.
    Type: Grant
    Filed: October 7, 2016
    Date of Patent: December 29, 2020
    Assignees: The Provost, Fellows, Scholars and Other Members of Board of Trinity College Dublin, University College Cork—National University of Ireland, Cork
    Inventors: Peter Fleming, Michael Morris, Thomas Fitzgerald, Ramesh Babu Padamati, Paul Delaney, Clifton Ngan, Niamh Hennessy, Kamran Beyzavi
  • Method of purifying a biological material of interest in a sample using nanofiber ultrafiltration membranes operated in tangential flow filtration mode
    Patent number: 10675588
    Abstract: Embodiments described herein relate to electrospun nanofiber ultrafiltration membrane compositions capable of operating in tangential filtration mode and methods of using the same.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: June 9, 2020
    Assignee: EMD Millipore Corporation
    Inventors: William Cataldo, Mikahil Kozlov, Alex Xenopoulos, Dennis Aquino, Clifton Ngan
  • A METHOD FOR THE PRODUCTION OF POLY(METHYL METHACRYLATE) (PMMA) MEMBRANES AND USES THEREOF
    Publication number: 20180284107
    Abstract: A poly(methyl methacrylate) (PMMA) membrane having a highly porous, reticulated, 3-D structure suitable for lateral flow diagnostic applications is described. Also described is a method for producing a poly(methyl methacrylate) (PMMA) membrane that comprises the steps of mixing a suitable amount of PMMA, a solvent and a optionally one of either a co-solvent or a non-solvent to produce a solution, casting a thin film of the solution onto a support, and removal of the solvent from the solution to produce the PMMA membrane. A lateral flow diagnostic device comprising a highly porous PMMA membrane as a reaction membrane is also described.
    Type: Application
    Filed: October 7, 2016
    Publication date: October 4, 2018
    Inventors: Peter Fleming, Michael Morris, Thomas Fitzgerald, Ramesh Babu, Paul Delaney, Clifton Ngan, Niamh Hennesey, Kamran Beyzavi
  • METHOD OF PURIFYING A BIOLOGICAL MATERIAL OF INTEREST IN A SAMPLE USING NANOFIBER ULTRAFILTRATION MEMBRANES OPERATED IN TANGENTIAL FLOW FILTRATION MODE
    Publication number: 20180085710
    Abstract: Embodiments described herein relate to electrospun nanofiber ultrafiltration membrane compositions capable of operating in tangential filtration mode and methods of using the same.
    Type: Application
    Filed: February 17, 2016
    Publication date: March 29, 2018
    Inventors: William Cataldo, Mikahil Kozlov, Alex Xenopoulos, Dennis Aquino, Clifton Ngan
  • High Viscosity TFF Device Design
    Publication number: 20140231339
    Abstract: A device for the tangential filtration of liquids at high viscosities is taught. For a given channel length and width (relatively fixed by the cassette design), one can decrease the channel pressure drop by increasing the channel height or reducing the channel hydraulic resistance. One can increase the channel height by using a larger diameter fiber in the screen, by increasing the thickness of the molded border or nm on the overmolded screen or by using a thicker nonwoven as a spacer in a non-overmolded screen. Since the screen is embossed into the surface of the membrane: the effective channel height Is also affected by the hardness of the membrane -as well as the fibers In the screen.
    Type: Application
    Filed: December 10, 2012
    Publication date: August 21, 2014
    Inventors: Clifton Ngan, Yu Zou, Brian Hillier, Andrew Bartlett