Patents by Inventor Clinton M. Yeung

Clinton M. Yeung has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for making 9-deoxotaxane compounds
    Patent number: 5616740
    Abstract: Process of making compounds having the formula ##STR1## wherein --OR.sup.1 comprises alkanoyl or the C-13 side-chain of taxol; R.sup.2, R.sup.3, and R.sup.6 can be oxygenated or hydrogen in various combinations; and R.sup.4 and R.sup.5 are acyl groups.
    Type: Grant
    Filed: May 11, 1995
    Date of Patent: April 1, 1997
    Assignee: Abbott Laboratories
    Inventors: Larry L. Klein, Clinton M. Yeung, Leping Li
  • 9-deoxotaxane compounds
    Patent number: 5440056
    Abstract: Compounds having the formula ##STR1## wherein --OR.sup.1 comprises alkanoyl or the C-13 side-chain of taxol; R.sup.2, R.sup.3, and R.sup.6 can be oxygenated or hydrogen in various combinations; and R.sup.4 and R.sup.5 are acyl groups,as well as a process for the preparation thereof, pharmaceutical compositions containing the above compounds, and a method for their use in inhibiting tumor growth.
    Type: Grant
    Filed: March 9, 1994
    Date of Patent: August 8, 1995
    Assignee: Abbott Laboratories
    Inventors: Larry L. Klein, Clinton M. Yeung, Leping Li
  • Erythromycin derivatives
    Patent number: 5288709
    Abstract: New 9-deoxo-9,12-epoxy erythromycin derivatives are disclosed which have improved antibacterial properties. Compositions comprising the erythromycin derivatives and methods of treating mammalian patients with the erythromycin derivatives are also disclosed.
    Type: Grant
    Filed: August 21, 1991
    Date of Patent: February 22, 1994
    Assignee: Abbott Laboratories
    Inventors: Leslie A. Freiberg, Larry L. Klein, Clinton M. Yeung, Carla M. Edwards, David J. Bacino
  • 1,3,2-benzodithiazole-1-oxide compounds
    Patent number: 5140018
    Abstract: Novel 1,3,2-benzodithiazole-1-oxides of formula (I) ##STR1## and their pharmaceutically acceptable salts are disclosed, wherein R.sup.1 is a substituent on the 4-, 5-, 6- or 7-position of the benzodithiazole nucleus selected from the group consisting of hydrogen, (C.sub.1 -C.sub.4)alkyl, halogen, halo(C.sub.1 -C.sub.4)alkyl, (C.sub.1 -C.sub.4)alkoxy, and nitro; andR.sup.2 is selected from the group consisting of (C.sub.1 -C.sub.12)alkyl; substituted (C.sub.1 -C.sub.12)alkyl; (C.sub.2 -C.sub.16)alkenyl; (C.sub.2 -C.sub.16)alkynyl; (C.sub.3 -C.sub.10)cycloalkyl; (C.sub.6 -C.sub.10)aryl; mono- or di-substituted (C.sub.6 -C.sub.10)aryl; (C.sub.6 -C.sub.10)aryl-(C.sub.1 -C.sub.4)alkyl; mono- or di-substituted (C.sub.6 -C.sub.10)aryl-(C.sub.1 -C.sub.4)alkyl; heterocycle-(C.sub.1 -C.sub.4)alkyl; and mono- or di-substituted heterocycle-(C.sub.1 -C.sub.4)alkyl.Also disclosed are the antifungal use and method of preparation of such compounds, as well as their formulation as pharmaceutical compositions.
    Type: Grant
    Filed: May 7, 1991
    Date of Patent: August 18, 1992
    Assignee: Abbott Laboratories
    Inventors: Larry L. Klein, Clinton M. Yeung