Patents by Inventor Clive Waldron

Clive Waldron has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for increasing butyrate production
    Patent number: 11931386
    Abstract: Provided herein are compositions and methods for increasing butyrate production in a subject. In particular, provided herein are compositions, probiotic compositions, and combinations thereof that promote butyrate production in a subject.
    Type: Grant
    Filed: August 29, 2018
    Date of Patent: March 19, 2024
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Thomas M. Schmidt, Nielson Baxter, Kwi Kim, Alexander Schmidt, Arvind Venkataraman, Clive Waldron
  • COMPOSITIONS AND METHODS FOR INCREASING BUTYRATE PRODUCTION
    Publication number: 20210077546
    Abstract: Provided herein are compositions and methods for increasing butyrate production in a subject. In particular, provided herein are compositions, probiotic compositions, and combinations thereof that promote butyrate production in a subject.
    Type: Application
    Filed: August 29, 2018
    Publication date: March 18, 2021
    Inventors: Thomas M. SCHMIDT, Nielson BAXTER, Kwi KIM, Alexander SCHMIDT, Arvind VENKATARAMAN, Clive WALDRON
  • Spinosyn-producing polyketide synthases
    Patent number: 9137992
    Abstract: The invention provides, biologically active spinosyns, hybrid spinosyn polyketide synthases capable of functioning in Saccharopolyspora spinosa to produce the spinosyns, and methods of controlling insects using the spinosyns.
    Type: Grant
    Filed: November 18, 2013
    Date of Patent: September 22, 2015
    Assignee: Dow AgroScienceas LLC
    Inventors: Lesley S. Burns, Paul Richard Graupner, Paul Lewer, Christine J. Martin, William A. Vousden, Clive Waldron, Barnie Wilkinson
  • SPINOSYN-PRODUCING POLYKETIDE SYNTHASES
    Publication number: 20140080777
    Abstract: The invention provides, biologically active spinosyns, hybrid spinosyn polyketide synthases capable of functioning in Saccharopolyspora spinosa to produce the spinosyns, and methods of controlling insects using the spinosyns.
    Type: Application
    Filed: November 18, 2013
    Publication date: March 20, 2014
    Applicant: DOW AGROSCIENCES LLC
    Inventors: Lesley S. Burns, Paul Richard Graupner, Paul Lewer, Christine J. Martin, William A. Vousden, Clive Waldron, Barnie Wilkinson
  • Spinosyn-producing polyketide synthases
    Patent number: 8624009
    Abstract: The invention provides, biologically active spinosyns, hybrid spinosyn polyketide synthases capable of functioning in Saccharopolyspora spinosa to produce the spinosyns, and methods of controlling insects using the spinosyns.
    Type: Grant
    Filed: March 28, 2011
    Date of Patent: January 7, 2014
    Assignee: Dow AgroSciences, LLC.
    Inventors: Lesley S. Burns, Paul R. Graupner, Paul Lewer, Christine J. Martin, William A. Vousden, Clive Waldron, Barrie Wilkinson
  • NOVEL SPINOSYN-PRODUCING POLYKETIDE SYNTHASES
    Publication number: 20110178036
    Abstract: The invention provides, biologically active spinosyns, hybrid spinosyn polyketide synthases capable of functioning in Saccharopolyspora spinosa to produce the spinosyns, and methods of controlling insects using the spinosyns.
    Type: Application
    Filed: March 28, 2011
    Publication date: July 21, 2011
    Inventors: Lesley S. Burns, Paul R. Graupner, Paul Lewer, Christine J. Martin, William A. Vousden, Clive Waldron, Barrie Wilkinson
  • SPINOSYN-PRODUCING POLYKETIDE SYNTHASES
    Publication number: 20100068785
    Abstract: The invention provides, biologically active spinosyns, hybrid spinosyn polyketide synthases capable of functioning in Saccharopolyspora spinosa to produce the spinosyns, and methods of controlling insects using the spinosyns.
    Type: Application
    Filed: November 11, 2009
    Publication date: March 18, 2010
    Inventors: Lesley S. Burns, Paul R. Graupner, Paul Lewer, Christine J. Martin, William A. Vousden, Clive Waldron, Barrie Wilkinson
  • Spinosyn-producing polyketide synthases
    Patent number: 7626010
    Abstract: The invention provides, biologically active spinosyns, hybrid spinosyn polyketide synthases capable of functioning in Saccharopolyspora spinosa to produce the spinosyns, and methods of controlling insects using the spinosyns.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: December 1, 2009
    Assignee: Dow AgroSciences LLC
    Inventors: Lesley S. Burns, Paul R. Graupner, Paul Lewer, Christine J. Martin, William A. Vousden, Clive Waldron, Barrie Wilkinson
  • DNA encoding SPNF of the spinosyn cluster
    Patent number: 7015001
    Abstract: Spinosyn biosynthetic genes from Saccharopolyspora spinosa, spinosyn producing microorganisms transformed with the biosynthetic genes, methods using the biosynthetic genes to increase production of spinosyn insecticidal macrolides, and methods using the genes or fragments thereof to change the products produced by spinosyn-producing microorganisms are provided.
    Type: Grant
    Filed: December 23, 2002
    Date of Patent: March 21, 2006
    Assignee: Dow AgroSciences LLC
    Inventors: Richard H. Baltz, M. Christine Broughton, Kathryn P. Crawford, Krishnamurthy Madduri, Donald J. Merlo, Patti J. Treadway, Jan R. Turner, Clive Waldron
  • Novel spinosyn-producing polyketide synthases
    Publication number: 20060040877
    Abstract: The invention provides, biologically active spinosyns, hybrid spinosyn polyketide synthases capable of functioning in Saccharopolyspora spinosa to produce the spinosyns, and methods of controlling insects using the spinosyns.
    Type: Application
    Filed: October 20, 2005
    Publication date: February 23, 2006
    Inventors: Lesley Burns, Paul Graupner, Paul Lewer, Christine Martin, William Vousden, Clive Waldron, Barrie Wilkinson
  • Biosynthetic genes for spinosyn insecticide production
    Publication number: 20040023343
    Abstract: Spinosyn biosynthetic genes, spinosyn producing microorganisms transformed with the biosynthetic genes, methods using the biosynthetic genes to increase production of spinosyn insecticidal macrolides, and methods using the genes or fragments thereof to change the products produced by spinosyn-producing microorganisms.
    Type: Application
    Filed: December 23, 2002
    Publication date: February 5, 2004
    Inventors: Richard H. Baltz, M. Christine Broughton, Kathryn P. Crawford, Krishnamurthy Madduri, Donald J. Merlo, Patti J. Treadway, Jan R. Turner, Clive Waldron
  • Novel spinosyn-producing polyketide synthases
    Publication number: 20030225006
    Abstract: The invention provides, biologically active spinosyns, hybrid spinosyn polyketide synthases capable of functioning in Saccharopolyspora spinosa to produce the spinosyns, and methods of controlling insects using the spinosyns.
    Type: Application
    Filed: February 19, 2003
    Publication date: December 4, 2003
    Inventors: Lesley S. Burns, Paul R. Graupner, Paul Lewer, Christine J. Martin, William A. Vousden, Clive Waldron, Barrie Wilkinson
  • SpnG, a gene for spinosyn insecticide biosynthesis
    Patent number: 6521406
    Abstract: Spinosyn biosynthetic genes from Saccharopolyspora spinosa, spinosyn producing microorganisms transformed with the biosynthetic genes, methods using the biosynthetic genes to increase production of spinosyn insecticidal macrolides, and methods using the genes or fragments thereof to change the products produced by spinosyn-producing microorganisms are provided.
    Type: Grant
    Filed: June 23, 2000
    Date of Patent: February 18, 2003
    Assignee: Dow AgroSciences LLC
    Inventors: Richard H. Baltz, M. Christine Broughton, Kathryn P. Crawford, Krishnamurthy Madduri, Donald J. Merlo, Patti J. Treadway, Jan R. Turner, Clive Waldron
  • Hygromycin-resistant transgenic plants
    Patent number: 6365799
    Abstract: The present invention is directed to hygromycin-resistant transgenic plants and methods for producing such plants. The transgenic plants of the invention comprise gene constructs which encode and express hygromycin phosphotransferase or functional portion thereof.
    Type: Grant
    Filed: February 9, 2000
    Date of Patent: April 2, 2002
    Assignee: Syngenta Participations AG
    Inventor: Clive Waldron
  • Biosynthetic genes for spinosyn insecticide production
    Patent number: 6274350
    Abstract: Spinosyn biosynthetic genes, spinosyn producing microorganisms transformed with the biosynthetic genes, methods using the biosynthetic genes to increase production of spinosyn insecticidal macrolides, and methods using the genes or fragments thereof to change the products produced by spinosyn-producing microorganisms.
    Type: Grant
    Filed: August 9, 1999
    Date of Patent: August 14, 2001
    Assignee: Dow AgroSciences LLC
    Inventors: Richard H. Baltz, Kathryn P. Crawford, M. Christine Broughton, Krishnamurthy Madduri, Donald J. Merlo, Jan R. Turner, Patti J. Treadway, Clive Waldron
  • Biosynthetic genes for spinosyn insecticide production
    Patent number: 6143526
    Abstract: Spinosyn biosynthetic genes, spinosyn producing microorganisms transformed with the biosynthetic genes, methods using the biosynthetic genes to increase production of spinosyn insecticidal macrolides, and methods using the genes or fragments thereof to change the products produced by spinosyn-producing microorganisms.
    Type: Grant
    Filed: March 9, 1998
    Date of Patent: November 7, 2000
    Inventors: Richard H. Baltz, M. Christine Broughton, Kathryn P. Crawford, Krishnamurthy Madduri, Donald J. Merlo, Patti J. Treadway, Jan R. Turner, Clive Waldron
  • Selectable marker for development of vectors and transformation systems in plants
    Patent number: 6048730
    Abstract: The present invention discloses functional and selectable micro-Ti plasmids. The hygromycin phosphotransferase (aphIV) gene from Escherichia coli was inserted between the 5' promoter and associated amino terminal region-encoding sequence of an octopine synthetase gene and the 3' terminator signal sequence of a nopaline synthetase gene. These constructs were assembled between T-DNA border fragments in a broad-host-range vector and used to create antibiotic-resistant plant cells.
    Type: Grant
    Filed: September 19, 1990
    Date of Patent: April 11, 2000
    Assignee: Novartis AG
    Inventor: Clive Waldron
  • Method of identifying potential fungicides using dihydroorotate dehydrogenase inhibition assay
    Patent number: 5976848
    Abstract: Dihydroorotate dehydrogenase (DHOD) inhibititon assays are utilized in a method for identifying new fungicides; DHOD inhibitors are useful in fungicidal methods and compositions. Resistance genes that are mutants of the wild-type Aspergillus nidulans dihydroorotate dehydrogenase gene have been isolated and found to impart resistance to certain DHOD inhibitors. The resistance genes are useful as selectable markers in fungi. The wild-type gene is also provided.
    Type: Grant
    Filed: January 30, 1992
    Date of Patent: November 2, 1999
    Assignee: Dow AgroSciences LLC
    Inventors: George E. Davis, Gary D. Gustafson, Matthew J. Henry, Amy J. Smith, Clive Waldron
  • Selectable marker for development of vectors and transformation systems in plants
    Patent number: 5668298
    Abstract: The present invention discloses functional and selectable micro-Ti plasmids. The hygromycin phosphotransferase (aphIV) gene from Escherichia coli was inserted between the 5' promoter and associated amino terminal region-encoding sequence of an octopine synthetase gene and the 3' terminator signal sequence of a nopaline synthetase gene. These constructs were assembled between T-DNA border fragments in a broad-host-range vector and used to create antibiotic-resistant plant cells.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: September 16, 1997
    Assignee: Eli Lilly and Company
    Inventor: Clive Waldron