Abstract: An occlusive device includes a frame element having a distal end and a proximal end, and a delivery configuration and a deployed configuration. The occlusive device also includes an occlusive face having a peripheral edge, where the occlusive face positioned toward the proximal end of the frame element. The occlusive device also includes at least one anchor positioned at the peripheral edge of the occlusive face, where the at least one anchor extends at an acute angle to the peripheral edge of the occlusive face.

Abstract: A device includes a plurality of elongate members, an occlusive component, and a support component. The occlusive component includes a plurality of first features each defined by a first portion of a respective elongate member. The support component includes a plurality of second features each defined by a second portion of the respective elongate member. A first termination element is defined by proximal end portions of the plurality of elongate members and located near a proximal end of the device, and a second termination element is defined by distal end portions of the plurality of elongate members and located near a distal end of the device. One or more anchor elements include a frame attachment portion and an anchor portion, the frame attachment portion including a first portion of a fixation elongate element wrapped around an elongate member, and the anchor portion including an anchor feature.

Abstract: A device includes a plurality of elongate members, an occlusive component, and a support component. The occlusive component includes a plurality of first features each defined by a first portion of a respective elongate member. The support component includes a plurality of second features each defined by a second portion of the respective elongate member. A first termination element is defined by proximal end portions of the plurality of elongate members and located near a proximal end of the device, and a second termination element is defined by distal end portions of the plurality of elongate members and located near a distal end of the device. One or more anchor elements include a frame attachment portion and an anchor portion, the frame attachment portion including a first portion of a fixation elongate element wrapped around an elongate member, and the anchor portion including an anchor feature.

Abstract: An occlusive device includes a frame element having a distal end and a proximal end, and a delivery configuration and a deployed configuration. The occlusive device also includes an occlusive face having a peripheral edge, where the occlusive face positioned toward the proximal end of the frame element. The occlusive device also includes at least one anchor positioned at the peripheral edge of the occlusive face, where the at least one anchor extends at an acute angle to the peripheral edge of the occlusive face.

Abstract: An occlusive device includes a frame element having a distal end and a proximal end, and a delivery configuration and a deployed configuration. The occlusive device also includes an occlusive face having a peripheral edge, where the occlusive face positioned toward the proximal end of the frame element. The occlusive device also includes at least one anchor positioned at the peripheral edge of the occlusive face, where the at least one anchor extends at an acute angle to the peripheral edge of the occlusive face.

Abstract: A device for occluding an aperture in a body of a patient includes a frame that includes a plurality of elongate members and a hub component that includes a plurality of attachment members, wherein for each elongate member of the plurality of elongate members a first end of the elongate member is fixedly attached to an attachment member of the plurality of attachment members at an attachment region. The frame and the hub component together form at least one occlusive element. Each receptacle of the plurality of attachment members is configured to pivot with respect to the hub component, such that each attachment region is movable with respect to the hub component.

Abstract: This disclosure is directed to an aperture occlusion device and a method for occluding an aperture, including a perimembranous ventricular septal defect. The aperture occlusion device includes a wire frame element. The wire frame forms geometric shapes that include an occluder region and a securing region. The occluder region and the securing region are separated by an attachment region including a waist. The occluder region and securing region can include membranous coverings. The device can be attached to a delivery hub. The wires forming the occluder region and securing region can have a shape-memory capability such that they can be collapsed and distorted in a sheath during delivery, but resume and maintain their intended shape after delivery.

Abstract: An occlusive device includes a frame element having a distal end and a proximal end, and a delivery configuration and a deployed configuration. The occlusive device also includes an occlusive face having a peripheral edge, where the occlusive face positioned toward the proximal end of the frame element. The occlusive device also includes at least one anchor positioned at the peripheral edge of the occlusive face, where the at least one anchor extends at an acute angle to the peripheral edge of the occlusive face.

Abstract: An occlusive device includes a frame element having a distal end and a proximal end, and a delivery configuration and a deployed configuration. The occlusive device also includes an occlusive face having a peripheral edge, where the occlusive face positioned toward the proximal end of the frame element. The occlusive device also includes at least one anchor positioned at the peripheral edge of the occlusive face, where the at least one anchor extends at an acute angle to the peripheral edge of the occlusive face.

Abstract: This disclosure is directed to an aperture occlusion device and a method for occluding an aperture, including a perimembranous ventricular septal defect. The aperture occlusion device includes a wire frame element. The wire frame forms geometric shapes that include an occluder region and a securing region. The occluder region and the securing region are separated by an attachment region including a waist. The occluder region and securing region can include membranous coverings. The device can be attached to a delivery hub. The wires forming the occluder region and securing region can have a shape-memory capability such that they can be collapsed and distorted in a sheath during delivery, but resume and maintain their intended shape after delivery.

Abstract: An occlusive device includes a frame element having a distal end and a proximal end, and a delivery configuration and a deployed configuration. The occlusive device also includes an occlusive face having a peripheral edge, where the occlusive face positioned toward the proximal end of the frame element. The occlusive device also includes at least one anchor positioned at the peripheral edge of the occlusive face, where the at least one anchor extends at an acute angle to the peripheral edge of the occlusive face.

Abstract: This disclosure is directed to an aperture occlusion device and a method for occluding an aperture, including a perimembranous ventricular septal defect. The aperture occlusion device includes a wire frame element. The wire frame forms geometric shapes that include an occluder region and a securing region. The occluder region and the securing region are separated by an attachment region including a waist. The occluder region and securing region can include membranous coverings. The device can be attached to a delivery hub. The wires forming the occluder region and securing region can have a shape-memory capability such that they can be collapsed and distorted in a sheath during delivery, but resume and maintain their intended shape after delivery.

Abstract: This disclosure is directed to an aperture occlusion device and a method for occluding an aperture, including a perimembranous ventricular septal defect. The aperture occlusion device includes a wire frame element. The wire frame forms geometric shapes that include an occluder region and a securing region. The occluder region and the securing region are separated by an attachment region including a waist. The occluder region and securing region can include membranous coverings. The device can be attached to a delivery hub. The wires forming the occluder region and securing region can have a shape-memory capability such that they can be collapsed and distorted in a sheath during delivery, but resume and maintain their intended shape after delivery.

Abstract: An occlusive device for left atrial appendage occlusion that has a membrane component configured to inhibit passage of blood and an expandable frame formed from a plurality of wires having a cupped occlusive component at least partially covered with the membrane component, one or more anchors with looped ends and a hub component. The occlusive device can be delivered percutaneously. The occlusive device is useful in the occlusion of the left atrial appendage.

Abstract: An occlusive device for left atrial appendage occlusion that has a membrane component configured to inhibit passage of blood and an expandable frame formed from a plurality of wires having a cupped occlusive component at least partially covered with the membrane component, one or more anchors with looped ends and a hub component. The occlusive device can be delivered percutaneously. The occlusive device is useful in the occlusion of the left atrial appendage.

Abstract: An occlusive device for left atrial appendage occlusion that has a membrane component configured to inhibit passage of blood and an expandable frame formed from a plurality of wires having a cupped occlusive component at least partially covered with the membrane component, one or more anchors with looped ends and a hub component. The occlusive device can be delivered percutaneously. The occlusive device is useful in the occlusion of the left atrial appendage.

Abstract: An occlusive device includes a frame element having a distal end and a proximal end, and a delivery configuration and a deployed configuration. The occlusive device also includes an occlusive face having a peripheral edge, where the occlusive face positioned toward the proximal end of the frame element. The occlusive device also includes at least one anchor positioned at the peripheral edge of the occlusive face, where the at least one anchor extends at an acute angle to the peripheral edge of the occlusive face.

Abstract: A device includes a plurality of elongate members, an occlusive component, and a support component. The occlusive component includes a plurality of first features each defined by a first portion of a respective elongate member. The support component includes a plurality of second features each defined by a second portion of the respective elongate member. A first termination element is defined by proximal end portions of the plurality of elongate members and located near a proximal end of the device, and a second termination element is defined by distal end portions of the plurality of elongate members and located near a distal end of the device. One or more anchor elements include a frame attachment portion and an anchor portion, the frame attachment portion including a first portion of a fixation elongate element wrapped around an elongate member, and the anchor portion including an anchor feature.

Abstract: A device for occluding an aperture in a body of a patient includes a frame that includes a plurality of elongate members and a hub component that includes a plurality of attachment members, wherein for each elongate member of the plurality of elongate members a first end of the elongate member is fixedly attached to an attachment member of the plurality of attachment members at an attachment region. The frame and the hub component together form at least one occlusive element. Each receptacle of the plurality of attachment members is configured to pivot with respect to the hub component, such that each attachment region is movable with respect to the hub component.

Abstract: An occlusive device includes a frame element having a distal end and a proximal end, and a delivery configuration and a deployed configuration. The occlusive device also includes an occlusive face having a peripheral edge, where the occlusive face positioned toward the proximal end of the frame element. The occlusive device also includes at least one anchor positioned at the peripheral edge of the occlusive face, where the at least one anchor extends at an acute angle to the peripheral edge of the occlusive face.