Abstract: A robotic system includes a multi-sectional show robot. The multi-sectional show robot includes a primary robot with a controller and one or more sensors. The one or more sensors are configured to acquire feedback indicative of an environment surrounding the primary robot. The multi-sectional show robot also includes a secondary robot configured to removably couple to the primary robot to transition the multi-sectional show robot between a disengaged configuration, in which the primary robot is decoupled from the secondary robot, and an engaged configuration, in which the primary robot is coupled to the secondary robot. The controller is configured to operate the primary robot based on the feedback and a first control scheme with the multi-sectional show robot in the disengaged configuration and to operate the primary robot based on a second control scheme with the multi-sectional show robot in the engaged configuration.

Abstract: An automated tissue section slicing, staining, and imaging system sequentially adheres tissue sections to a continuous substrate such that the staining, imaging, and interpretation of the tissue sections are readily carried out at high speed under machine control.

Abstract: An electrochromic device and method of cloaking an electrochromic device is disclosed. The electrochromic device can include a first transparent conductive layer on a substrate, a second transparent conductive layer, a cathodic electrochromic layer between the first transparent conductive layer and the second transparent conductive layer, and an anodic electrochromic layer between the first transparent conductive layer and the second transparent conductive layer. The stack of layers can be patterned to be parallel to a voltage gradient of the electrochromic device and extend through all layers of the electrochromic device. The electrochromic device can also include a masking layer that covers the patterned inactive area. A method can include determining a pattern of inactive areas within a visible area, determining a cloaking pattern that corresponds to the pattern of inactive areas, and depositing a masking layer in the areas of the cloaking pattern.

Abstract: A robotic system includes a multi-sectional show robot. The multi-sectional show robot includes a primary robot with a controller and one or more sensors. The one or more sensors are configured to acquire feedback indicative of an environment surrounding the primary robot. The multi-sectional show robot also includes a secondary robot configured to removably couple to the primary robot to transition the multi-sectional show robot between a disengaged configuration, in which the primary robot is decoupled from the secondary robot, and an engaged configuration, in which the primary robot is coupled to the secondary robot. The controller is configured to operate the primary robot based on the feedback and a first control scheme with the multi-sectional show robot in the disengaged configuration and to operate the primary robot based on a second control scheme with the multi-sectional show robot in the engaged configuration.

Abstract: The present disclosure relates to methods and apparatuses for sectioning and imaging tissue or other samples, which are then automatically captured to enable subsequent analysis. The apparatus acts as a slice capture mechanism for serial sectioning microscopy in a fashion which enables subsequent interfacing with secondary microscopic interrogations or for processing with molecular diagnostic tools. The slices are spatially indexed to allow specific slices to be recalled from a library via automated handling techniques described herein.

Abstract: The following concerns a method for co-localization of microscopy or histology stains by the assembly of a virtual image from one or more imaging operations. In particular, the method decreases the time required to obtain multiple labeled antigen or protein histology images of a biological sample. The method includes imaging the tissue as it is sliced by a microtome with a knife edge scanning microscope and spatially aligning the samples by the generated images. The spatial alignment of samples enabled by the method allows a panel of different antigen or protein secondary or functional stains to be compared across different sample slices, thereby allowing concurrent secondary stains of tissues and cells.

Abstract: A measurement system and methods for collecting measurement data for features of ceramic matrix composite (CMC) components are provided. In one aspect, the system and methods provided herein can be utilized to collect measurement data for a cooling hole of a CMC component. The measurement system includes a sensor system that includes a chromatic confocal sensor and a charged coupled device. The chromatic confocal sensor emits stacked cones of light each having an associated wavelength. The stacked cones are moved over a target surface of the CMC component and the charged coupled device measures one or more characteristics associated with the reflected light. The characteristics are then used by a computing device to generate a measurement data file representative of the geometric profile of the cooling hole. A rotary table system can position the CMC component to present the cooling hole at different orientations.

Abstract: The following concerns a method for co-localization of microscopy or histology stains by the assembly of a virtual image from one or more imaging operations. In particular, the method decreases the time required to obtain multiple labeled antigen or protein histology images of a biological sample. The method includes imaging the tissue as it is sliced by a microtome with a knife edge scanning microscope and spatially aligning the samples by the generated images. The spatial alignment of samples enabled by the method allows a panel of different antigen or protein secondary or functional stains to be compared across different sample slices, thereby allowing concurrent secondary stains of tissues and cells.

Abstract: A measurement system and methods for collecting measurement data for features of ceramic matrix composite (CMC) components are provided. In one aspect, the system and methods provided herein can be utilized to collect measurement data for a cooling hole of a CMC component. The measurement system includes a sensor system that includes a chromatic confocal sensor and a charged coupled device. The chromatic confocal sensor emits stacked cones of light each having an associated wavelength. The stacked cones are moved over a target surface of the CMC component and the charged coupled device measures one or more characteristics associated with the reflected light. The characteristics are then used by a computing device to generate a measurement data file representative of the geometric profile of the cooling hole. A rotary table system can position the CMC component to present the cooling hole at different orientations.

Abstract: An automated tissue section slicing, staining, and imaging system sequentially adheres tissue sections to a continuous substrate such that the staining, imaging, and interpretation of the tissue sections are readily carried out at high speed under machine control.

Abstract: A data center includes a computer room with one or more regions, where each region includes air handling components which can be independently controlled, relative to components in other regions. A purge control system in each region can bypass a control system which adjusts the components based on environmental sensor data to command the components to purge the region. Upon the components in a region entering a purge mode, a purge notification signal can be sent to a master control system, which can instruct other control systems in other non-purging regions to limit controller output ranges to last-known values prior to the purge, so that the components in other regions are operated at last-known states while one or more regions are purging. When regions have ceased purging, the regional control systems can re-establish the control loop output ranges. Such re-establishment can include incrementally expanding the output range over time.

Abstract: A datacenter room can be associated with multiple computer room air handling units (CRAHUS) capable of transitioning between cooling modes. A management component of the datacenter can separate transitions of different CRAHUS by time intervals. Durations of the time intervals may be determined based on ambient air temperature.

Abstract: The following concerns a method for co-localization of microscopy or histology stains by the assembly of a virtual image from one or more imaging operations. In particular, the method decreases the time required to obtain multiple labeled antigen or protein histology images of a biological sample. The method includes imaging the tissue as it is sliced by a microtome with a knife edge scanning microscope and spatially aligning the samples by the generated images. The spatial alignment of samples enabled by the method allows a panel of different antigen or protein secondary or functional stains to be compared across different sample slices, thereby allowing concurrent secondary stains of tissues and cells.

Abstract: The present disclosure relates to methods and apparatuses for sectioning and imaging tissue or other samples, which are then automatically captured to enable subsequent analysis. The apparatus acts as a slice capture mechanism for serial sectioning microscopy in a fashion which enables subsequent interfacing with secondary microscopic interrogations or for processing with molecular diagnostic tools. The slices are spatially indexed to allow specific slices to be recalled from a library via automated handling techniques described herein.

Abstract: Motion strategies in two and three dimensions for scanning microscope imaging are described. An object, sample, or specimen is mounted on a precision three-dimensional stage. The object is moved concurrently with respect to a first axis and a second axis orthogonal to the first against a cutting tool to cut the object. An image of the cut portion is generated as the object is moved. The cutting tool may act as an optical waveguide for illuminating the portion of the object cut. An optical element captures images of the cut and illuminated object. The object may further be concurrently moved with respect to a third axis orthogonal to both the first and second.