Abstract: The present disclosure is directed towards improved systems and methods for large-scale production of nanoparticles used for delivery of therapeutic material. The apparatus can be used to manufacture a wide array of nanoparticles containing therapeutic material including, but not limited to, lipid nanoparticles and polymer nanoparticles. In certain embodiments, continuous flow operation and parallelization of microfluidic mixers contribute to increased nanoparticle production volume.

Abstract: This application discusses, among other things, agricultural equipment and more particularly agricultural chemical applicators. In an example, an agricultural sprayer system can include a first boom section configured to receive a carrier material and a chemical material and to provide an agricultural chemical mixture, the boom section having a plurality of nozzles for spraying the chemical mixture; and a first rod insert coupled to an end cap of the boom section, the rod insert configured to reduce the volume of the boom section and to provide increased flow velocity of the chemical mixture to each of the plurality of nozzles.

Abstract: This application discusses, among other things, agricultural equipment and more particularly agricultural chemical applicators. In an example, an agricultural sprayer system can include a first boom section configured to receive a carrier material and a chemical material and to provide an agricultural chemical mixture, the boom section having a plurality of nozzles for spraying the chemical mixture; and a first rod insert coupled to an end cap of the boom section, the rod insert configured to reduce the volume of the boom section and to provide increased flow velocity of the chemical mixture to each of the plurality of nozzles.