Abstract: A seal is disclosed having a pair of side walls, a base extending between the side walls, a first concave surface extending inwardly from one of the side walls, a second concave surface extending inwardly from the other side wall, and a convex surface extending between the first concave and second concave surface to form a rounded peak having an apex. The seal has a seal width defined between the seal side walls, and a seal height defined between the apex of the rounded peak and the base. The width is at least twice the height of the seal. The seal is located in a channel recess of a first component opposite a second component to seal between the first component and the second component, the channel recess having a floor and a height defined between the floor and a surface of the first component in which the channel recess is formed.

Abstract: A system is disclosed for additively manufacturing a composite structure. The system may include a support, a discharge head connected to and moveable by the support, a supply of reinforcement, and a rotary tensioner located between the supply and the discharge head. The rotary tensioner may be configured to impart tension to the reinforcement and to generate a signal indicative of the tension. The system may further include a drive associated with the supply, and a controller in communication with the rotary tensioner and the drive. The controller may be configured to selectively adjust a feed parameter of the drive based on the signal to maintain a desired level of tension.

Abstract: The present disclosure relates generally to a polypeptide having esterase activity, more specifically, to a polypeptide comprising an amino acid sequence that has at least 80% identity to amino acids 2-257 of SEQ ID NO: 1.

Abstract: An electrical assembly comprises a plurality of modules (36), each module (36) including at least one switching element (38) and at least one energy storage device (40), the or each switching element (38) and the or each energy storage device (40) in each module (36) arranged to be combinable to selectively provide a voltage source, wherein each module (36) includes a respective sensor (46) that is configured to monitor at least one other of the plurality of modules (36), each sensor (46) configured to selectively detect an occurrence of an operational hazard in the or each corresponding monitored module (36).

Abstract: A device attaches an animal carrier to a bicycle. The device includes an adjustable arm having a first end and a second end. The adjustable arm includes a bicycle coupling at the first end, for securing the arm to the bicycle. The adjustable arm further includes a carrier mount at the second end, for mounting the animal carrier to the arm. The arm is adjustable such that the carrier mount is rotatable relative to the bicycle coupling.

Abstract: The present disclosure relates to a nucleic acid molecule comprising 5?-UTR and/or 3?-UTR sequences that yield high translation levels. Aspects of the disclosure further relate to nucleic acid molecules suitable for use as a vaccine in the treatment and prevention of infectious diseases, including those caused by a coronavirus, compositions comprising said nucleic acid molecules and methods of treating or preventing infectious diseases.

Abstract: Provided are drainage systems that may include a drainage manifold and may be suitable for draining fluid from a tissue site. The drainage manifold may include a plurality of elongate members having a moveable end that may be adapted to configure the drainage manifold to treat a uniquely shaped tissue site. The drainage manifold may be coupled to a drainage tube with a transitional connector to provide a drainage system capable of distributing reduced pressure to the tissue site to enhance the drainage of fluids.

Abstract: A hybrid fluid heating system for heating a production fluid using fuel and/or electric energy sources, the production fluid being contained in a pressure vessel includes a fuel-fired furnace heating subsystem, comprising: a furnace configured provide a thermal transfer fluid; and a heat exchanger configured to receive the thermal transfer fluid from the furnace and configured to be in thermal communication with the production fluid to provide convective heat exchange from the thermal transfer fluid to the production fluid; an electrical heating subsystem comprising one or more electrical heating elements disposed at least partially within the pressure vessel and being in contact with the production fluid; and wherein the fuel-fired furnace heating subsystem and the electrical heating subsystem are each configured to be individually controlled such that the production fluid is selectively heated by at least one of the fuel-fired furnace heating subsystem and the electrical heating subsystem.

Abstract: A Unified Content Delivery Network system (UCDN) system which is formed from a network of one or more inter-operable Peer networks. A hierarchical hybrid adaptive Secure Peer-Assisted Networking System (termed SPAN-AI), using a hierarchical AI driven approach under a unified secure content-addressable architecture which is based on five key SPAN-AI sub systems: unified naming; unified discovery; hybrid adaptive routing; scalable pubsub; and embedded security; all of said five key SPAN-AI sub systems securely integrated and jointly optimized via a hierarchical, pluggable AI framework, with an associated simulation, training, and development pipeline that embeds AI agents with varying degrees of awareness and optimization capabilities at peer, edge, or core or other network levels (hierarchies).

Abstract: The present disclosure relates generally to a polypeptide having mono-(2-hydroxyethyl) terephthalate hydrolase (MHETase) activity, more specifically to a polypeptide comprising an amino acid sequence that (i) has at least 70% sequence identity to SEQ ID NO:1 and (ii) differs from SEQ ID NO:1 by an amino acid substitution at one or more positions selected from the group consisting of positions that correspond to amino acid positions 156 to 396, 398 to 410 and 425 to 603 of SEQ ID NO:1.

Abstract: A reduced-pressure system for treating a tissue site on a patient includes a distribution manifold that adheres to a tissue site to allow retention without external support. The distribution manifold includes a porous member and a tissue-fixation element. The tissue-fixation element maintains the porous member substantially adjacent to the tissue site while a sealing member is applied. In one instance, the tissue-fixation element is a soluble adhesive that partially covers either the tissue-facing side of the porous member or a tissue-facing side of a fluid-permeable substrate layer that is on the tissue-facing side of the porous member. Other systems, distributions manifolds, and methods are presented.

Abstract: In some examples, a dressing filler for treating a tissue site may include a plurality of filler elements and a tissue interface layer. Each of the filler elements may include a first surface and a second surface opposite the first surface and separated from the first surface by a thickness. The tissue interface layer may include a first side configured to be positioned facing the tissue site and a second side positioned opposite the first side. The first surface of each of the filler elements may be coupled to the second side of the tissue interface layer. Also provided are other apparatuses, dressings, systems, and methods suitable for treating a tissue site.

Abstract: Provided are drainage systems that may include a drainage manifold and may be suitable for draining fluid from a tissue site. The drainage manifold may include a plurality of elongate members having a moveable end that may be adapted to configure the drainage manifold to treat a uniquely shaped tissue site. The drainage manifold may be coupled to a drainage tube with a transitional connector to provide a drainage system capable of distributing reduced pressure to the tissue site to enhance the drainage of fluids.

Abstract: A reduced-pressure system for treating a tissue site on a patient includes a distribution manifold that adheres to a tissue site to allow retention without external support. The distribution manifold includes a porous member and a tissue-fixation element. The tissue-fixation element maintains the porous member substantially adjacent to the tissue site while a sealing member is applied. In one instance, the tissue-fixation element is a soluble adhesive that partially covers either the tissue-facing side of the porous member or a tissue-facing side of a fluid-permeable substrate layer that is on the tissue-facing side of the porous member. Other systems, distributions manifolds, and methods are presented.

Abstract: In one embodiment, a network switch for an information handling system includes: a central processing unit (CPU); and a fan module removably coupled to the network switch, the fan module including: a housing having a front end and a back end; a plurality of fans disposed within the housing proximate to the back end; a memory interface disposed within the housing proximate to the front end, the memory interface communicably coupled to the CPU; a memory device disposed within the housing proximate to the memory interface, the memory device storing information associated with the networking operations and communicably coupled to the memory interface, the memory device removably coupled to the fan module.

Abstract: A negative pressure wound treatment (NPWT) system including a NWPT therapy unit and a wound dressing configured to overlay a wound bed. The NPWT system includes a first length of tubing comprising a first end and a second end, the first end of the first length of tubing coupled to the NWPT therapy unit and the second end of the first length of tubing having a first coupling half, as well as a second length of tubing having a first end and second end, the first end of the second length of tubing coupled to the wound dressing and the second end of the second length of tubing having a second coupling half. The NPWT system includes an inline filter comprising a sintered polymer and a superabsorbent material, and an inline coupling, wherein the inline coupling is configured to operably couple and de-couple the NPWT therapy unit and wound dressing.

Abstract: Disclosed embodiments relate to devices and systems for providing negative-pressure therapy, instillation, and/or pressure-sensing at a tissue site, and to methods of manufacturing such devices and systems. In some embodiments, a fluid bridge may comprise a first layer of foam with a plurality of supports extending from at least an inner surface, and a second layer. The first and second layers may be coupled together around the perimeter to form one or more enclosed fluid pathways, for example extending from a port to an aperture. In some embodiments, at least the first layer may be formed of closed-cell foam.

Abstract: An aerosol forming component for volatilizing a liquid in an aerosol delivery device is disclosed. The aerosol forming component includes a first aerosol-forming member configured to be heated up to a first operating temperature and thereafter to a second higher operating temperature, and a second aerosol-forming member configured to be heated up to at least the first operating temperature as the first aerosol-forming member reaches the second higher operating temperature so that liquid volatilized from the two aerosol-forming members mix with one another.

Abstract: A treatment system for applying negative pressure therapy and fluid instillation treatment to a tissue site, particularly an abdominal tissue site, is disclosed. In some embodiments, the treatment system may include a dressing member, a plurality of fluid removal pathways, a fluid instillation matrix, a drape, a negative-pressure source, and a fluid instillation source. Instillation fluid may be delivered from the fluid instillation source to the tissue site through the fluid instillation matrix, and negative pressure may be communicated and fluid withdrawn from the tissue site through the plurality of fluid removal pathways.

Abstract: A computer implemented method for generating parameters associated with at least one consumption event within a domicile, the method having the steps of identifying at least one consumption event selected from the group consisting of water usage, energy usage, and product usage, generating data by at least one input data source within the domicile, collecting the data, and, processing the data with the computer to calculate the parameters associated with the at least one consumption event.