Abstract: The present invention relates to optical fiber pressure sensors. In one embodiment, liquid pressure of an environment may be measured based on capillary action occurring within an optical fiber having one or more hollow columns within. In another embodiment, the change in environmental pressure may be measured based on light diffracted from an optical fiber having optical grating. In either embodiment, the pressure sensor is manufactured from a single optical fiber.

Abstract: A method and system of ablating tissue under optical coherence tomography guidance including inserting an optical coherence tomography catheter into a patient's vasculature; navigating the catheter to a target site; imaging and mapping target tissue at the target site using the catheter; delivering a light-activated therapeutic agent into the target tissue; and illuminating the light-activated therapeutic agent with light emitted from the catheter, thereby activating the therapeutic agent and ablating the target tissue; establishing coordinates of the target tissue under computer tomography imaging whereby the catheter provides a marker visible under computer tomography imaging for establishing a positional relationship between the catheter and the target tissue, establishing a localized magnetic field in the target tissue on the basis of the coordinates obtained during the computer tomography imaging and where the light-activated therapeutic agent is magnetized and substantially retained within the target ti