Abstract: The invention relates to a system for inflating tire tubes, more specifically the inflation of bicycle tire tubes either a SCHRADER or PRESTA type inflation valve. In one embodiment, a conduit having an internal gas passage threadably connects the tire tube inflation valve to a sealed cartridge containing a requisite volume of pressurized gas to inflate a mounted tire. A pointed puncture tube mounted at the inlet end of the conduit and forming a portion of the internal passage, ruptures the cartridge seal when the cartridge is connected to the conduit. The gas flow through this ruptured seal is controllable by a seal around the puncture tube that contacts the cartridge seal. Attachment means and seal elements contained within the conduit prevent loss of the pressurized gas during tube inflation. A gas-tight connection to the tube inflation valve is created by a resilient coupling member mounted at the outlet end of the conduit.