Abstract: Disclosed herein are compounds that are Hematopoietic Progenitor Kinase 1 (HPK1) inhibitors having a structure according to Formula I, and compositions containing those compounds. Methods of preparing the compounds, and methods of using the compounds for the treatment of diseases, disorders, or conditions are also described.

Abstract: An initial image is subjected to a plurality of segmentations into uniform components by using various criteria to identify and isolate several series of objects constituted by segmented thumbnail images associated with geometrical descriptors for boxes that cover said objects, the results of the segmentation methods are fused, numerical values are used to characterize each object thumbnail image that results from fusion, and each of the thumbnail images is compared with indexed thumbnail images in an indexed database containing a set of textual descriptions for everyday elementary objects. The list of textual descriptions of everyday elementary objects matching the object thumbnail images that result from the segmentation and fusion operations is provided together with pertinence levels.

Abstract: In the method, correlated achromatic single-plane images are subjected to a plurality of operations for segmenting them into uniform components on the basis of different criteria. The results of the various segmentation operations for each of the processed correlated images are analyzed in order to generate cores constituted by zones presenting high certainty as to the existence of objects. The resulting cores are compared and those zones which correspond to more than some determined threshold of the various cores are conserved as indicating the presence of an object. The previously processed images are subjected to a weighted summing operation in order to obtain a first result image containing the uniform component cores. The first result image is then subjected to coloring followed by binarization in order to obtain a second result image containing the uniform components, and the individualized objects are extracted from the image.

Abstract: An initial image is subjected to a plurality of segmentations into uniform components by using various criteria to identify and isolate several series of objects constituted by segmented thumbnail images associated with geometrical descriptors for boxes that cover said objects, the results of the segmentation methods are fused, numerical values are used to characterize each object thumbnail image that results from fusion, and each of the thumbnail images is compared with indexed thumbnail images in an indexed database containing a set of textual descriptions for everyday elementary objects. The list of textual descriptions of everyday elementary objects matching the object thumbnail images that result from the segmentation and fusion operations is provided together with pertinence levels.

Abstract: In the method, correlated achromatic single-plane images are subjected to a plurality of operations for segmenting them into uniform components on the basis of different criteria. The results of the various segmentation operations for each of the processed correlated images are analyzed in order to generate cores constituted by zones presenting high certainty as to the existence of objects. The resulting cores are compared and those zones which correspond to more than some determined threshold of the various cores are conserved as indicating the presence of an object. The previously processed images are subjected to a weighted summing operation in order to obtain a first result image containing the uniform component cores. The first result image is then subjected to coloring followed by binarization in order to obtain a second result image containing the uniform components, and the individualized objects are extracted from the image.

Abstract: The method of the present invention overcomes the hot-sticking problems between an inorganic non-metallic material (=insulator) to be molded and a forming die by maintaining an assembly comprising a forming die and the insulator in a polarized state during molding. Processes using said method lead to an improved surface quality of the molded insulator. A device for reducing said hot-sticking comprises a die (2) which acts as conductor, an electrode (3) which may act as support for the insulator (1) to be molded, means (5) for polarizing the assembly of said conductor, insulator and electrode which means (5) are connected by live electric wires (4) with said die and electrode.