Patents by Inventor Cornelis van't Veer

Cornelis van't Veer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR DETERMINING THE RISK OF A THROMBOEMBOLIC EVENT
    Publication number: 20220252624
    Abstract: The invention relates to a method of determining the bleeding risk of a subject comprising: a. contacting a first sample from the subject with an activation mixture comprising (I) TIX-5, (II) factor Xa or an activation agent for activating directly or indirectly the conversion of factor X to factor Xa, and (III) a phospholipid mixture, b. determining the value of a coagulation function parameter of said sample, c. comparing the coagulation function parameter with a control value, d. determining the bleeding risk based on a comparison between the value of said coagulation function parameter of said first sample and said control value.
    Type: Application
    Filed: June 15, 2020
    Publication date: August 11, 2022
    Inventors: Cornelis VAN 'T VEER, Anja MAAG
  • Methods and active substances for protecting organs
    Patent number: 6924267
    Abstract: The present invention comprises a method of protecting organs or tissue susceptible to reperfusion-induced dysfunction after ischemia. The method comprises parenterally administering to a patient a therapeutical composition containing natural alpha-1 acid glycoprotein, natural alpha-1 antitrypsin or a mixture thereof. Alternatively, organ or tissue transplants can be contacted with natural alpha-1 acid glycoprotein, natural alpha-antitrypsin or mixtures by perfusing or flushing them with a solution containing natural alpha-1 acid glycoprotein, natural alpha-1 antitrypsin or mixtures thereof in a concentration of 0.1 to 5 g/l.
    Type: Grant
    Filed: September 18, 2001
    Date of Patent: August 2, 2005
    Assignee: Suomen Punainen Risti Veripalvelu
    Inventors: Marc A. R. C. Daemen, Vincent H. Heemskerk, Cornelis van't Veer, Geertrui Denecker, Tim G. A. M. Wolfs, Peter Vandenabeele, Wim A. Buurman, Jaakko Parkkinen
  • Thrombosis prophylaxis for factor Vleiden carriers
    Patent number: 6248548
    Abstract: Persons having the Factor VLEIDEN mutation and a lower than average plasma level of TFPI have been found to be at elevated risk of thrombosis. Prophylactic methods for reducing the risk of thrombosis employ the administration of TFPI to achieve higher levels in the plasma.
    Type: Grant
    Filed: November 1, 1999
    Date of Patent: June 19, 2001
    Assignee: The University of Vermont and State Agriculture College
    Inventors: Cornelis Van't Veer, Michael Kalafatis, Kenneth G. Mann
  • Thrombosis prophylaxis for factor V.sup.LEIDEN carriers
    Patent number: 5977057
    Abstract: Persons having the Factor V.sup.LEIDEN mutation and a lower than average plasma level of TFPI have been found to be at elevated risk of thrombosis. Prophylactic methods for reducing the risk of thrombosis employ the administration of TFPI to achieve higher levels in the plasma.
    Type: Grant
    Filed: May 8, 1996
    Date of Patent: November 2, 1999
    Assignee: The University of Vermont and State Agricultural College
    Inventors: Cornelis Van't Veer, Michael Kalafatis, Kenneth G. Mann