Patents by Inventor Cory Pelletier

Cory Pelletier has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Single Nucleotide Polymorphisms in BRCA1 and Cancer Risk
    Publication number: 20150025230
    Abstract: The invention provides methods for identifying mutations, such as single nucleotide polymorphisms (SNPs), within breast and ovarian cancer associated genes that modify the binding efficacy of microRNAs (miRNAs). In a preferred embodiment, methods of the invention identify a SNP that decreases expression of the BRCA1 gene by increasing or decreasing the binding efficacy of at least one miRNA. Alteration of miRNA binding to BRCA1 by the introduction of SNPs within miRNA binding sites modulates or decreases BRCA1 expression, ultimately leading to the unregulated cell proliferation of a breast or ovarian cancer cells.
    Type: Application
    Filed: August 26, 2013
    Publication date: January 22, 2015
    Applicant: YALE UNIVERSITY
    Inventors: Joanne B. Weidhaas, Cory Pelletier
  • SINGLE NUCLEOTIDE POLYMORPHISMS IN BRCA1 AND CANCER RISK
    Publication number: 20120156676
    Abstract: The invention provides methods for identifying mutations, such as single nucleotide polymorphisms (SNPs), within breast and ovarian cancer associated genes that modify the binding efficacy of microRNAs (miRNAs). In a preferred embodiment, methods of the invention identify a SNP that decreases expression of the BRCA1 gene by increasing or decreasing the binding efficacy of at least one miRNA. Alteration of miRNA binding to BRCA1 by the introduction of SNPs within miRNA binding sites modulates or decreases BRCA1 expression, ultimately leading to the unregulated cell proliferation of a breast or ovarian cancer cells.
    Type: Application
    Filed: June 25, 2010
    Publication date: June 21, 2012
    Inventors: Joanne B. Weidhaas, Cory Pelletier