Patents by Inventor Craig Buxton

Craig Buxton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PYRIDINE DERIVATIVES AS TMEM16A MODULATORS FOR USE IN THE TREATMENT OF RESPIRATORY CONDITIONS
    Publication number: 20220235006
    Abstract: Compounds of general formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9 and R10 are as defined herein are useful for treating respiratory disease and other diseases and conditions modulated by TMEM16A.
    Type: Application
    Filed: January 21, 2022
    Publication date: July 28, 2022
    Inventors: Stephen COLLINGWOOD, Craig BUXTON, Jonathan David HARGRAVE, Peter INGRAM, Thomas Beauregard SCHOFIELD, Abdul SHAIKH, Christopher STIMSON
  • PYRIDINE DERIVATIVES AS CALCIUM-ACTIVATED CHLORIDE CHANNEL MODULATORS
    Publication number: 20220144803
    Abstract: Compounds of general formula (I), wherein R1, R2, R3, R4, R5, X1, X2 and X3 are as defined herein are useful for treating respiratory disease and other diseases and conditions modulated by TMEM16A.
    Type: Application
    Filed: January 21, 2022
    Publication date: May 12, 2022
    Inventors: Stephen COLLINGWOOD, Craig BUXTON, Matthew HABGOOD, Jonathan David HARGRAVE, Thomas Beauregard SCHOFIELD, Matthew SMITH, Christopher STIMSON
  • Compounds
    Publication number: 20200383988
    Abstract: Compounds of general formula (1): wherein R1, R2, R3, R4, R5a, R* X1, X2, Z and Y are as defined herein are positive modulators of the N H calcium-activated chloride channel (CaCC), TMEM16A. The compounds are useful for treating diseases and conditions affected by modulation of TMEM16A, particularly respiratory diseases and conditions.
    Type: Application
    Filed: November 22, 2019
    Publication date: December 10, 2020
    Inventors: Stephen Collingwood, Clive Mccarthy, Jonathan David Hargrave, Duncan Alexander Hay, Thomas Beauregard Schofield, Sarah Ellam, Craig Buxton, Matthew Habgood, Peter Ingram, Chun Yan Ma, Spencer Napier, Abdul Shaikh, Matthew Smith, Christopher Stimson, Edward Walker
  • COMPOUNDS
    Publication number: 20200361871
    Abstract: Compounds of general formula (I): wherein R1, R2, R3, R4, R5a, R5b X1, X2, Z and Y are as defined herein are positive modulators of the calcium-activated chloride channel (CaCC), TMEM16A. The compounds are useful for treating diseases and conditions affected by modulation of TMEM16A, particularly respiratory diseases and conditions.
    Type: Application
    Filed: July 30, 2020
    Publication date: November 19, 2020
    Inventors: Stephen Collingwood, Clive Mccarthy, Jonathan David Hargrave, Duncan Alexander Hay, Thomas Beauregard Schofield, Sarah Ellam, Craig Buxton, Matthew Habgood, Peter Ingram, Chun Yan Ma, Spencer Napier, Abdul Shaikh, Matthew Smith, Christopher Stimson, Edward Walker
  • Mechanism for automatically lifting a trailer drawbar support
    Patent number: 8840129
    Abstract: A trailer adapted to be coupled to a tow vehicle and including a frame including a draw bar tube defining a longitudinal axis. The trailer includes a drawbar support pivotally coupled to the draw bar tube and rotatable relative to the drawbar tube about an axis parallel to the longitudinal axis. The drawbar support is biased toward a substantially horizontal orientation. A sliding member is receivable in the drawbar tube and is configured for movement along the longitudinal axis in response to movement of the tow vehicle. A latch member is connected to the sliding member. The latch member is configured to move in response to movement of the sliding member from a first position wherein the drawbar support is retained in a substantially vertical orientation to a second position wherein the draw bar support is free to rotate toward the substantially horizontal orientation.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: September 23, 2014
    Assignee: Clark Equipment Company
    Inventors: Peter Edgeller, Craig Buxton
  • MECHANISM FOR AUTOMATICALLY LIFTING A TRAILER DRAWBAR SUPPORT
    Publication number: 20140035258
    Abstract: A trailer adapted to be coupled to a tow vehicle and including a frame including a drawbar tube defining a longitudinal axis. The trailer includes a drawbar support pivotally coupled to the drawbar tube and rotatable relative to the tube about an axis parallel to the longitudinal axis. The drawbar support is biased toward a substantially horizontal orientation. A sliding member is receivable in the tube and is configured for movement along the longitudinal axis in response to movement of the tow vehicle. A latch member is connected to the sliding member. The latch member is configured to move in response to movement of the sliding member from first position wherein the drawbar support is retained in a substantially vertical orientation to a second position wherein the drawbar support is free to rotate toward the substantially horizontal orientation.
    Type: Application
    Filed: March 15, 2013
    Publication date: February 6, 2014
    Inventors: Peter Edgeller, Craig Buxton