Patents by Inventor Craig M. Lewis

Craig M. Lewis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chiral imidazole fungicidal compositions and methods for their use
    Patent number: 6207695
    Abstract: Chiral fungicides and compositions containing the same are provided. Also provided are methods for using the compositions of the present invention for inhibiting the growth of fungi, including phytotoxic fungi. The use of a single isomer in treating particular plant species and against particular fungi allows for selective inhibition of fungal growth with reduced fungicidal phytotoxic effects.
    Type: Grant
    Filed: December 23, 1999
    Date of Patent: March 27, 2001
    Assignee: Celgene Corporation
    Inventors: Richard A. Nelson, Norman W. Thomas, George W. Matcham, Sue L. Lin, Minghua Zhang, Craig M. Lewis
  • Enzymatic synthesis of chiral amines using -2-amino propane as amine donor
    Patent number: 6133018
    Abstract: 2-Aminopropane is used as the amine donor in the stereoselective synthesis of a chiral amine from a ketone with a transaminase. In a typical embodiment, (S)-1-methoxy-2-aminopropane is prepared by bringing methoxyacetone into contact with a transaminase in the presence of 2-aminopropane as an amine donor until a substantial amount of methoxyacetone is converted to (S)-1-methoxy-2-aminopropane and 2-aminopropane is converted to acetone. In a second embodiment, L-alanine is prepared by bringing pyruvic acid into contact with a transaminase in the presence of 2-aminopropane as an amine donor.
    Type: Grant
    Filed: March 10, 1999
    Date of Patent: October 17, 2000
    Assignee: Celgro
    Inventors: Wei Wu, Mohit B. Bhatia, Craig M. Lewis, Wei Lang, Alice L. Wang, George W. Matcham