Patents by Inventor Cristina Cuesico

Cristina Cuesico has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptides and methods for the detection of Lyme disease antibodies
    Patent number: 11573227
    Abstract: The invention provides compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VlsE protein. The invention also provides devices, methods, and kits comprising such peptide compositions and useful for the detection of antibodies that bind to Borrelia antigens and the diagnosis of Lyme disease.
    Type: Grant
    Filed: January 14, 2021
    Date of Patent: February 7, 2023
    Assignee: ZOETIS SERVICES LLC
    Inventors: Rajesh K. Mehra, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico
  • Signal amplification in lateral flow and related immunoassays
    Patent number: 11255854
    Abstract: The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample. The methods, devices, and compositions utilize detectable Fc-binding molecules such as Protein A, Protein G, and/or an Fc-specific antibody to amplify the signal of a detected antibody in immunoassays, such as lateral flow assays.
    Type: Grant
    Filed: March 20, 2019
    Date of Patent: February 22, 2022
    Assignee: Zoetis Services LLC
    Inventors: Rajesh K. Mehra, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico
  • PEPTIDES AND METHODS FOR THE DETECTION OF LYME DISEASE ANTIBODIES
    Publication number: 20210140964
    Abstract: The invention provides compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VlsE protein. The invention also provides devices, methods, and kits comprising such peptide compositions and useful for the detection of antibodies that bind to Borrelia antigens and the diagnosis of Lyme disease.
    Type: Application
    Filed: January 14, 2021
    Publication date: May 13, 2021
    Inventors: Rajesh K. MEHRA, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico
  • Peptides and methods for the detection of Lyme disease antibodies
    Patent number: 10921321
    Abstract: The invention provides compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VlsE protein. The invention also provides devices, methods, and kits comprising such peptide compositions and useful for the detection of antibodies that bind to Borrelia antigens and the diagnosis of Lyme disease.
    Type: Grant
    Filed: September 10, 2018
    Date of Patent: February 16, 2021
    Assignee: Abaxis, Inc.
    Inventors: Rajesh K. Mehra, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico
  • SIGNAL AMPLIFICATION IN LATERAL FLOW AND RELATED IMMUNOASSAYS
    Publication number: 20190219572
    Abstract: The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample. The methods, devices, and compositions utilize detectable Fc-binding molecules such as Protein A, Protein G, and/or an Fc-specific antibody to amplify the signal of a detected antibody in immunoassays, such as lateral flow assays.
    Type: Application
    Filed: March 20, 2019
    Publication date: July 18, 2019
    Inventors: Rajesh K. MEHRA, Kenneth P. ARON, Dennis M. BLEILE, Jeremy WALKER, Cristina CUESICO
  • Signal amplification in lateral flow and related immunoassays
    Patent number: 10281465
    Abstract: The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample. The methods, devices, and compositions utilize detectable Fc-binding molecules such as Protein A, Protein G, and/or an Fc-specific antibody to amplify the signal of a detected antibody in immunoassays, such as lateral flow assays.
    Type: Grant
    Filed: February 1, 2018
    Date of Patent: May 7, 2019
    Assignee: ABAXIS, INC.
    Inventors: Rajesh K. Mehra, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico
  • PEPTIDES AND METHODS FOR THE DETECTION OF LYME DISEASE ANTIBODIES
    Publication number: 20180372743
    Abstract: The invention provides compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VlsE protein. The invention also provides devices, methods, and kits comprising such peptide compositions and useful for the detection of antibodies that bind to Borrelia antigens and the diagnosis of Lyme disease.
    Type: Application
    Filed: September 10, 2018
    Publication date: December 27, 2018
    Inventors: Rajesh K. MEHRA, Kenneth P. ARON, Dennis M. BLEILE, Jeremy WALKER, Cristina CUESICO
  • Peptides and methods for the detection of lyme disease antibodies
    Patent number: 10073095
    Abstract: The invention provides compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VlsE protein. The invention also provides devices, methods, and kits comprising such peptide compositions and useful for the detection of antibodies that bind to Borrelia antigens and the diagnosis of Lyme disease.
    Type: Grant
    Filed: August 23, 2017
    Date of Patent: September 11, 2018
    Assignee: Abaxis, Inc.
    Inventors: Rajesh K. Mehra, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico
  • SIGNAL AMPLIFICATION IN LATERAL FLOW AND RELATED IMMUNOASSAYS
    Publication number: 20180156790
    Abstract: The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample. The methods, devices, and compositions utilize detectable Fc-binding molecules such as Protein A, Protein G, and/or an Fc-specific antibody to amplify the signal of a detected antibody in immunoassays, such as lateral flow assays.
    Type: Application
    Filed: February 1, 2018
    Publication date: June 7, 2018
    Inventors: Rajesh K. MEHRA, Kenneth P. ARON, Dennis M. BLEILE, Jeremy WALKER, Cristina CUESICO
  • Signal amplification in lateral flow and related immunoassays
    Patent number: 9921218
    Abstract: The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample. The methods, devices, and compositions utilize detectable Fc-binding molecules such as Protein A, Protein G, and/or an Fc-specific antibody to amplify the signal of a detected antibody in immunoassays, such as lateral flow assays.
    Type: Grant
    Filed: April 16, 2015
    Date of Patent: March 20, 2018
    Assignee: ABAXIS, INC.
    Inventors: Rajesh K. Mehra, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico
  • PEPTIDES AND METHODS FOR THE DETECTION OF LYME DISEASE ANTIBODIES
    Publication number: 20170356910
    Abstract: The invention provides compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VlsE protein. The invention also provides devices, methods, and kits comprising such peptide compositions and useful for the detection of antibodies that bind to Borrelia antigens and the diagnosis of Lyme disease.
    Type: Application
    Filed: August 23, 2017
    Publication date: December 14, 2017
    Inventors: Rajesh K. MEHRA, Kenneth P. ARON, Dennis M. BLEILE, Jeremy WALKER, Cristina CUESICO
  • Peptides and methods for the detection of lyme disease antibodies
    Patent number: 9766238
    Abstract: The invention provides compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VlsE protein. The invention also provides devices, methods, and kits comprising such peptide compositions and useful for the detection of antibodies that bind to Borrelia antigens and the diagnosis of Lyme disease.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: September 19, 2017
    Assignee: ABAXIS, INC.
    Inventors: Rajesh K. Mehra, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico
  • PEPTIDES AND METHODS FOR THE DETECTION OF LYME DISEASE ANTIBODIES
    Publication number: 20160109446
    Abstract: The invention provides compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VlsE protein. The invention also provides devices, methods, and kits comprising such peptide compositions and useful for the detection of antibodies that bind to Borrelia antigens and the diagnosis of Lyme disease.
    Type: Application
    Filed: October 27, 2015
    Publication date: April 21, 2016
    Inventors: Rajesh K. MEHRA, Kenneth P. ARON, Dennis M. BLEILE, Jeremy WALKER, Cristina CUESICO
  • Peptides and methods for the detection of lyme disease antibodies
    Patent number: 9201071
    Abstract: The invention provides compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VlsE protein. The invention also provides devices, methods, and kits comprising such peptide compositions and useful for the detection of antibodies that bind to Borrelia antigens and the diagnosis of Lyme disease.
    Type: Grant
    Filed: June 13, 2014
    Date of Patent: December 1, 2015
    Assignee: ABAXIS, INC.
    Inventors: Rajesh K. Mehra, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico
  • SIGNAL AMPLIFICATION IN LATERAL FLOW AND RELATED IMMUNOASSAYS
    Publication number: 20150293088
    Abstract: The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample. The methods, devices, and compositions utilize detectable Fc-binding molecules such as Protein A, Protein G, and/or an Fc-specific antibody to amplify the signal of a detected antibody in immunoassays, such as lateral flow assays.
    Type: Application
    Filed: April 16, 2015
    Publication date: October 15, 2015
    Inventors: Rajesh K. MEHRA, Kenneth P. ARON, Dennis M. BLEILE, Jeremy WALKER, Cristina CUESICO
  • Signal amplification in lateral flow and related immunoassays
    Patent number: 9034656
    Abstract: The present invention provides methods, devices, compositions (e.g., capture complexes), and kits useful for enhancing the detection of antibodies in a test sample. The methods, devices, and compositions utilize detectable Fc-binding molecules such as Protein A, Protein G, and/or an Fc-specific antibody to amplify the signal of a detected antibody in immunoassays, such as lateral flow assays.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: May 19, 2015
    Assignee: ABAXIS, INC.
    Inventors: Rajesh K. Mehra, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico
  • PEPTIDES AND METHODS FOR THE DETECTION OF LYME DISEASE ANTIBODIES
    Publication number: 20140364332
    Abstract: The invention provides compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VlsE protein. The invention also provides devices, methods, and kits comprising such peptide compositions and useful for the detection of antibodies that bind to Borrelia antigens and the diagnosis of Lyme disease.
    Type: Application
    Filed: June 13, 2014
    Publication date: December 11, 2014
    Inventors: Rajesh K. MEHRA, Kenneth P. ARON, Dennis M. BLEILE, Jeremy WALKER, Cristina CUESICO
  • Peptides and methods for the detection of lyme disease antibodies
    Patent number: 8758772
    Abstract: The invention provides compositions (e.g., peptide compositions) useful for the detection of antibodies that bind to Borrelia antigens. The peptide compositions comprise polypeptide sequences comprising variants in the IR6 domain of the Borrelia VlsE protein. The invention also provides devices, methods, and kits comprising such peptide compositions and useful for the detection of antibodies that bind to Borrelia antigens and the diagnosis of Lyme disease.
    Type: Grant
    Filed: November 2, 2012
    Date of Patent: June 24, 2014
    Assignee: Abaxis, Inc.
    Inventors: Rajesh K. Mehra, Kenneth P. Aron, Dennis M. Bleile, Jeremy Walker, Cristina Cuesico