Patents by Inventor Cristina Magdalena Mueller

Cristina Magdalena Mueller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 18F-labelled folate/antifolate analogues
    Patent number: 10357576
    Abstract: The present invention is directed towards new 18F-folate/antifolate analog radiopharmaceuticals, wherein the phenyl group within folate structures has been replaced by an 18F-heterocycle, their precursors, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.
    Type: Grant
    Filed: May 8, 2013
    Date of Patent: July 23, 2019
    Assignee: MERECK & CIE
    Inventors: Roger Schibli, Rudolf Moser, Cristina Magdalena Mueller, Simon Mensah Ametamey, Thomas Betzel, Viola Groehn
  • Method for cell-specific targeting
    Patent number: 9265746
    Abstract: Method for selective targeting of one or more effector moiety such as diagnostic or a therapeutic agent to a cell or population of cells expressing a folate-receptor comprising simultaneous or sequential administration of an antifolate with a folate- or pteroate-conjugate comprising said one or more effector moiety.
    Type: Grant
    Filed: May 31, 2006
    Date of Patent: February 23, 2016
    Assignee: MERCK & CIE
    Inventors: Rudolf Moser, Viola Groehn, Roger Schibli, Cristina Magdalena Mueller
  • 18F-LABELLED FOLATE/ANTIFOLATE ANALOGUES
    Publication number: 20150125390
    Abstract: The present invention is directed towards new 18F-folate/antifolate analogue radiopharmaceuticals, wherein the phenyl group within folate structures has been replaced by an 18F-heterocycle, their precursors, a method of their preparation, as well as their use in diagnosis of a cell or population of cells expressing a folate-receptor and monitoring of cancer and inflammatory and autoimmune diseases and therapy thereof.
    Type: Application
    Filed: May 8, 2013
    Publication date: May 7, 2015
    Applicant: MERCK & CIE
    Inventors: Roger Schibli, Rudolf Moser, Cristina Magdalena Mueller, Simon Mensah Ametamey, Thomas Betzel, Viola Groehn
  • Method for cell-specific targeting
    Publication number: 20070280880
    Abstract: Method for selective targeting of one or more effector moiety such as diagnostic or a therapeutic agent to a cell or population of cells expressing a folate-receptor comprising simultaneous or sequential administration of an antifolate with a folate- or pteroate-conjugate comprising said one or more effector moiety.
    Type: Application
    Filed: May 31, 2006
    Publication date: December 6, 2007
    Inventors: Rudolf Moser, Viola Groehn, Roger Schibli, Cristina Magdalena Mueller