Abstract: The invention discloses a method for constructing functional exosomes capable of efficiently loading specific miRNA. In order to enable the exosome to carry miRNA with specific regulation function more efficiently so as to play a role in targeted regulation more accurately and efficiently, MS2 phage capsid protein is utilized to edit and construct a capture element of a specific miRNA molecule, and placenta mesenchymal stem cells are reprogrammed to enable the secreted exosome to efficiently load a target miRNA molecule, so that the target miRNA molecule is delivered to tissue cells to play a role in effective regulation, and therefore a new strategy is provided for realizing specific precise treatment in the future.

Abstract: The present disclosure relates to a lithium ion battery including an electrode assembly; and an electrolytic solution for infiltrating the electrode assembly and an electrical apparatus including the same, wherein the electrode assembly includes an electrode body, a positive electrode tab, and a negative electrode tab. The electrode body includes a positive electrode plate, a negative electrode plate, and a separator that are wound together around an axis. The positive electrode plate includes a positive current collector and a positive electrode material layer provided on at least one surface of the positive electrode current collector. In an axial direction (X), the electrode body has two opposite side portions, and the positive electrode tab and the negative electrode tab extend from the two side portions of the electrode body, respectively. A diffusion rate v of the electrolytic solution to the electrode body is from 0.01 ?g/s to 5 ?g/s.

Abstract: A method for determining a patterning device pattern. The method includes obtaining (i) an initial patterning device pattern having at least one feature, and (ii) a desired feature size of the at least one feature, obtaining, based on a patterning process model, the initial patterning device pattern and a target pattern for a substrate, a difference value between a predicted pattern of the substrate image by the initial patterning device and the target pattern for the substrate, determining a penalty value related the manufacturability of the at least one feature, wherein the penalty value varies as a function of the size of the at least one feature, and determining the patterning device pattern based on the initial patterning device pattern and the desired feature size such that a sum of the difference value and the penalty value is reduced.

Abstract: This application relates to lithium-ion batteries and related battery modules, battery packs and devices. Specifically, the lithium-ion battery includes a positive electrode plate, a negative electrode plate, an electrolyte, and a separator, wherein the positive electrode plate includes aluminum foil as a positive electrode current collector, and a content of element copper atom as an impurity per unit area of the aluminum foil is from 0.009 g/m2 to 0.021 g/m2, and the electrolyte contains first lithium salt and additive A, and the first lithium salt is a fluorine-containing sulfonimide lithium salt, and relative to total molar amount of lithium salt in the electrolyte, the fluorine-containing sulfonimide lithium salt has a molar amount of 30 mol % or higher; and the additive A is at least one of a phosphate compound containing an unsaturated bond, a cyclic compound containing a —SO2— bond and a silicon-oxygen compound containing an unsaturated bond.

Abstract: The present application relates to a lithium ion battery, comprising: a positive electrode plate, a negative electrode plate, a separator disposed between the positive electrode plate and the negative electrode plate, and an electrolytic solution, the positive electrode plate including a positive electrode current collector and a positive electrode active material layer provided on at least one side of the positive electrode current collector, and the electrolytic solution including an organic solvent, a lithium salt and an additive, wherein the lithium salt comprises a primary lithium salt, the primary lithium salt is a first compound in an amount of 30% or more relative to the total molar amount of the lithium salt, and the first compound has a structure represented by the following formula I, and wherein the additive comprises a second compound represented by the following formula II.

Abstract: The present disclosure provides a lithium ion battery including a positive electrode plate, a negative electrode plate, a separator, and an electrolyte. The positive electrode plate includes a positive electrode current collector, and a positive electrode film disposed on a surface of the positive electrode current collector and containing a positive electrode active material. The positive electrode active material includes a matrix, a first coating layer on the matrix in form of discrete islands, and a second coating layer on the first coating layer and the matrix as a continuous layer. The electrolyte includes an additive A and an additive B. The additive A is selected from a group consisting of cyclic sulfate compounds represented by Formula 1 and Formula 2, and combinations thereof, and the additive B is one or two selected from lithium difluorobisoxalate phosphate and lithium tetrafluorooxalate phosphate.

Abstract: The present application relates to a lithium ion battery, comprising: a positive electrode plate, a negative electrode plate, a separator disposed between the positive electrode plate and the negative electrode plate, and an electrolytic solution, the positive electrode plate including a positive electrode current collector and a positive electrode active material layer provided on at least one side of the positive electrode current collector, and the electrolytic solution including an organic solvent, a lithium salt and an additive, wherein the lithium salt comprises a primary lithium salt, the primary lithium salt is a first compound in an amount of 30% or more relative to the total molar amount of the lithium salt, and the first compound has a structure represented by the following formula I, and wherein the additive comprises a second compound represented by the following formula II.

Abstract: The present disclosure relates to a lithium ion battery including an electrode assembly; and an electrolytic solution for infiltrating the electrode assembly and an electrical apparatus including the same, wherein the electrode assembly includes an electrode body, a positive electrode tab, and a negative electrode tab. The electrode body includes a positive electrode plate, a negative electrode plate, and a separator that are wound together around an axis. The positive electrode plate includes a positive current collector and a positive electrode material layer provided on at least one surface of the positive electrode current collector. In an axial direction (X), the electrode body has two opposite side portions, and the positive electrode tab and the negative electrode tab extend from the two side portions of the electrode body, respectively. A diffusion rate v of the electrolytic solution to the electrode body is from 0.01 ?g/s to 5 ?g/s.

Abstract: The present disclosure provides an electrolyte and a lithium-ion battery. The electrolyte includes an electrolyte salt, an organic solvent and additives. The additives include a first additive that is one or more selected from compounds shown as Formula 1, and a second additive that is one or more selected from compounds shown as Formula 2. The first additive and the second additive act synergistically and can effectively reduce the DCR growth of a lithium-ion battery during use.

Abstract: The present disclosure provides a lithium ion battery including a positive electrode plate, a negative electrode plate, a separator, and an electrolyte. The positive electrode plate includes a positive electrode current collector, and a positive electrode film disposed on a surface of the positive electrode current collector and containing a positive electrode active material. The positive electrode active material includes a matrix, a first coating layer on the matrix in form of discrete islands, and a second coating layer on the first coating layer and the matrix as a continuous layer. The electrolyte includes an additive A and an additive B. The additive A is selected from a group consisting of cyclic sultone compounds represented by Formula 1 and Formula 2, and combinations thereof, and the additive B is one or two selected from lithium difluorobisoxalate phosphate and lithium tetrafluorooxalate phosphate.

Abstract: The present disclosure provides a lithium ion battery including a positive electrode plate, a negative electrode plate, a separator, and an electrolyte. The positive electrode plate includes a positive electrode current collector, and a positive electrode film disposed on a surface of the positive electrode current collector and containing a positive electrode active material. The positive electrode active material includes a matrix, a first coating layer on the matrix in form of discrete islands, and a second coating layer on the first coating layer and the matrix as a continuous layer. The electrolyte includes an additive A and an additive B. The additive A is selected from a group consisting of cyclic sulfate compounds represented by Formula 1 and Formula 2, and combinations thereof, and the additive B is one or two selected from lithium difluorobisoxalate phosphate and lithium tetrafluorooxalate phosphate.

Abstract: A method to improve a lithographic process for imaging a portion of a design layout onto a substrate using a lithographic projection apparatus, the method including: computing a multi-variable cost function of a plurality of design variables that are characteristics of the lithographic process, and reconfiguring the characteristics of the lithographic process by adjusting the design variables until a predefined termination condition is satisfied. The multi-variable cost function may be a function of one or more pattern shift errors. Reconfiguration of the characteristics may be under one or more constraints on the one or more pattern shift errors.

Abstract: The present invention provides a lithium ion battery and an electrolyte thereof. The electrolyte for the lithium ion battery includes a non-aqueous organic solvent, a lithium salt and additives, wherein the additives include additive A cyclophosphazene compound, additive B lithium fluorophosphate compound, and additive C selected from at least one of silane phosphate compound, silane phosphite compound and silane borate compound. Compared with conventional technologies, the nickel-rich positive electrode lithium ion battery using the electrolyte of the present invention has a desirable cyclic capacity retention rate, a desirable storage capacity retention rate and a low gas production at high temperature, and has a low DC internal resistance at low temperature, which can remarkably improve the thermal stability of lithium ion battery.