Patents by Inventor Cunqi Cui

Cunqi Cui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
    Patent number: 11844878
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: December 19, 2023
    Assignee: Allergan, Inc.
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina
  • CO-CROSSLINKED HYALURONIC ACID-SILK FIBROIN HYDROGELS FOR IMPROVING TISSUE GRAFT VIABILITY AND FOR SOFT TISSUE AUGMENTATION
    Publication number: 20200376159
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Application
    Filed: August 14, 2020
    Publication date: December 3, 2020
    Inventors: Xiaojie YU, Darin J. MESSINA, Elizabeta PAVLOVIC, Cunqi CUI, Kate M. SMITHER
  • Co-crosslinked hyaluronic acid-silk fibroin hydrogels for improving tissue graft viability and for soft tissue augmentation
    Patent number: 10744227
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Grant
    Filed: May 1, 2019
    Date of Patent: August 18, 2020
    Assignee: ALLERGAN, INC.
    Inventors: Xiaojie Yu, Darin J. Messina, Elizabeta Pavlovic, Cunqi Cui, Kate M. Smither
  • VASCULAR GRAFTS DERIVED FROM ACELLULAR TISSUE MATRICES
    Publication number: 20200101195
    Abstract: A vascular graft for treatment of diseased or damaged blood vessels is disclosed. The graft comprises a sheet of acellular tissue matrix with an intact basement membrane. The graft is formed by wrapping the sheet into a tube and securing the edges of the sheet together. The acellular tissue matrix facilitates tissue ingrowth and remodeling of the graft with host cells.
    Type: Application
    Filed: November 25, 2019
    Publication date: April 2, 2020
    Inventors: Hui Xu, Cunqi Cui, Joshua Czeczuga, Jared Lombardi
  • Vascular grafts derived from acellular tissue matrices
    Patent number: 10525164
    Abstract: A vascular graft for treatment of diseased or damaged blood vessels is disclosed. The graft comprises a sheet of acellular tissue matrix with an intact basement membrane. The graft is formed by wrapping the sheet into a tube and securing the edges of the sheet together. The acellular tissue matrix facilitates tissue ingrowth and remodeling of the graft with host cells.
    Type: Grant
    Filed: August 24, 2010
    Date of Patent: January 7, 2020
    Assignee: LifeCell Corporation
    Inventors: Hui Xu, Cunqi Cui, Joshua Czeczuga, Jared Lombardi
  • CROSSLINKED HYALURONIC ACID-COLLAGEN GELS FOR IMPROVING TISSUE GRAFT VIABILITY AND SOFT TISSUE AUGMENTATION
    Publication number: 20200000968
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Application
    Filed: July 31, 2019
    Publication date: January 2, 2020
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina
  • CO-CROSSLINKED HYALURONIC ACID-SILK FIBROIN HYDROGELS FOR IMPROVING TISSUE GRAFT VIABILITY AND FOR SOFT TISSUE AUGMENTATION
    Publication number: 20190255215
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Application
    Filed: May 1, 2019
    Publication date: August 22, 2019
    Inventors: Xiaojie YU, Darin J. MESSINA, Elizabeta PAVLOVIC, Cunqi CUI, Kate M. SMITHER
  • NERVE TREATMENT DEVICES AND METHODS
    Publication number: 20190216977
    Abstract: Devices and methods for treating defects in peripheral nerves are provided. The devices can include acellular arterial tissue matrices that facilitate regrowth of nerve tissue across a gap or defect in a peripheral nerve.
    Type: Application
    Filed: January 24, 2019
    Publication date: July 18, 2019
    Inventors: Hui Xu, Wendell Sun, Cunqi Cui, Hua Wan
  • Co-crosslinked hyaluronic acid-silk fibroin hydrogels for improving tissue graft viability and for soft tissue augmentation
    Patent number: 10300169
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Grant
    Filed: August 24, 2017
    Date of Patent: May 28, 2019
    Assignee: Allergan, Inc.
    Inventors: Xiaojie Yu, Darin J. Messina, Elizabeta Pavlovic, Cunqi Cui, Kate M. Smither
  • CO-CROSSLINKED HYALURONIC ACID-SILK FIBROIN HYDROGELS FOR IMPROVING TISSUE GRAFT VIABILITY AND FOR SOFT TISSUE AUGMENTATION
    Publication number: 20180055971
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.
    Type: Application
    Filed: August 24, 2017
    Publication date: March 1, 2018
    Inventors: Xiaojie YU, Darin J. MESSINA, Elizabeta PAVLOVIC, Cunqi CUI, Kate M. SMITHER
  • CROSSLINKED HYALURONIC ACID-COLLAGEN GELS FOR IMPROVING TISSUE GRAFT VIABILITY AND SOFT TISSUE AUGMENTATION
    Publication number: 20170348463
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Application
    Filed: August 25, 2017
    Publication date: December 7, 2017
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina
  • Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
    Patent number: 9782517
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: October 10, 2017
    Assignee: Allergan, Inc.
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina
  • CROSSLINKED HYALURONIC ACID-COLLAGEN GELS FOR IMPROVING TISSUE GRAFT VIABILITY AND SOFT TISSUE AUGMENTATION
    Publication number: 20170224873
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Application
    Filed: April 24, 2017
    Publication date: August 10, 2017
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina
  • Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
    Patent number: 9662422
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Grant
    Filed: November 6, 2014
    Date of Patent: May 30, 2017
    Assignee: Allergan, Inc.
    Inventors: Jacob F. Pollock, Lauren E. Kokai, Cunqi Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina
  • CROSSLINKED HYALURONIC ACID-COLLAGEN GELS FOR IMPROVING TISSUE GRAFT VIABILITY AND SOFT TISSUE AUGMENTATION
    Publication number: 20150064147
    Abstract: Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a collagen component.
    Type: Application
    Filed: November 6, 2014
    Publication date: March 5, 2015
    Applicant: Allergan, Inc.
    Inventors: Jacob F. Pollock, Lauren E. Kokai, CUNQI Cui, Xiaojie Yu, Dennis E. Van Epps, Darin J. Messina
  • NERVE TREATMENT DEVICES AND METHODS
    Publication number: 20110135706
    Abstract: Devices and methods for treating defects in peripheral nerves are provided. The devices can include acellular arterial tissue matrices that facilitate regrowth of nerve tissue across a gap or defect in a peripheral nerve.
    Type: Application
    Filed: November 30, 2010
    Publication date: June 9, 2011
    Inventors: Hui Xu, Wendell Sun, Cunqi Cui, Hua Wan
  • VASCULAR GRAFTS DERIVED FROM ACELLULAR TISSUE MATRICES
    Publication number: 20110054588
    Abstract: A vascular graft for treatment of diseased or damaged blood vessels is disclosed. The graft comprises a sheet of acellular tissue matrix with an intact basement membrane. The graft is formed by wrapping the sheet into a tube and securing the edges of the sheet together. The acellular tissue matrix facilitates tissue ingrowth and remodeling of the graft with host cells.
    Type: Application
    Filed: August 24, 2010
    Publication date: March 3, 2011
    Inventors: Hui Xu, Cunqi Cui, Joshua Czeczuga, Jared Lombardi
  • Elimination of endogenous porcine retrovirus
    Publication number: 20060107337
    Abstract: Porcine nucleic acid sequences flanking potentially infectious porcine endogenous retroviral (PERV) insertion sites have been identified and isolated. The unique flanking sequences include porcine nucleic acid sequences that flank the 3? end and porcine nucleic acid sequences that flank the 5? end of PERV insertion sites. The present invention provides compositions and methods for detecting presence of PERV in a sample, particularly those with infectious potential. In addition, the invention relates to breeding of pigs or selection of porcine tissue that is free of infectious PERV for use as a xenotransplant tissue.
    Type: Application
    Filed: December 30, 2005
    Publication date: May 18, 2006
    Inventors: Cunqi Cui, Lisa Diamond, John Logan
  • Elimination of endogenous porcine retrovirus
    Patent number: 7038107
    Abstract: Porcine nucleic acid sequences flanking potentially infectious porcine endogenous retroviral (PERV) insertion sites have been identified and isolated. The unique flanking sequences include porcine nucleic acid sequences that flank the 3? end and porcine nucleic acid sequences that flank the 5? end of PERV insertion sites. The present invention provides compositions and methods for detecting presence of PERV in a sample, particularly those with infectious potential. In addition, the invention relates to breeding of pigs or selection of porcine tissue that is free of infectious PERV for use as a xenotransplant tissue.
    Type: Grant
    Filed: March 28, 2002
    Date of Patent: May 2, 2006
    Assignee: Mayo Foundation for Medical Education and Research
    Inventors: Cunqi Cui, Lisa E. Diamond, John S. Logan